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Karamichali E1, Foka P2, Tsitoura E2, Kalliampakou K2, Kazazi D2, Karayiannis P3, Georgopoulou U2, Mavromara P4.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.Infect Genet Evol.2014 May 9. pii: S1567-1348(14)00137-3. doi: 10.1016/j.meegid.2014.04.015. [Epub ahead of print]
Translation initiation of the Hepatitis C virus (HCV) genome is driven by an internal ribosome entry site (IRES), located within the 5' non-coding region. Several studies have suggested that different cellular non canonical proteins or viral proteins can regulate the HCV IRES activity. However, the
PMID 24815730

NS2 proteins of GB virus B and hepatitis C virus share common protease activities and membrane topologies.

Boukadida C1, Marnata C, Montserret R, Cohen L, Blumen B, Gouttenoire J, Moradpour D, Penin F, Martin A.
Journal of virology.J Virol.2014 Apr 16. [Epub ahead of print]
GB virus B (GBV-B), which is hepatotropic in experimentally infected small New World primates, is a member of the Hepacivirus genus but phylogenetically relatively distant to hepatitis C virus (HCV). To gain insight into the role and specificity of hepaciviral nonstructural protein 2 (NS2), which is
PMID 24741107

Li T1, Zhu S, Shuai L, Xu Y, Yin S, Bian Y, Wang Y, Zuo B, Wang W, Zhao S, Zhang L, Zhang J, Gao GF, Allain JP, Li C.
Hepatology (Baltimore, Md.).Hepatology.2014 Mar;59(3):789-802. doi: 10.1002/hep.26750. Epub 2014 Jan 16.
The development of vaccination and novel therapy for hepatitis C virus (HCV) has been hampered by the lack of suitable small-animal models. GB virus B (GBV-B), closely related to HCV, causes viral hepatitis in common marmosets (Callithrix jacchue jacchus) and might represent an attractive surrogate
PMID 24123143