WordNet

a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
the 7th letter of the Roman alphabet (同)g

Japanese Journal

Interaction between Gα12 and Gα13 protein subunits and dopamine receptors in renal proximal tubules

PESTANA Manuel
Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension 34(9), 987-988, 2011-09-01
NAID 10030275868

GPCRによるRho活性化の新展開--GPCRシグナルと進行癌 (第5土曜特集最新 G蛋白質共役受容体研究--疾患解明とシグナル制御の新時代) -- (受容体の解析・制御のあらたな視点)

小笹徹
医学のあゆみ 233(9), 680-686, 2010-05-29
NAID 40017107046

The Scaffold Protein c-Jun NH2-Terminal Kinase-associated Leucine Zipper Protein Regulates Cell Migration through Interaction with the G Protein G13

Gantulga Davaakhuu,Tuvshintugs Baljinnyam,Endo Yoshio [他],Takino Takahisa,Sato Hiroshi,Murakami Seishi,Yoshioka Katsuji
The journal of biochemistry 144(6), 693-700, 2008-12-01
… whereas, a C-terminal deletion mutant of mouse JLP, which failed to bind the G protein Gα13, showed little or no effect on the cell migration defect. … Furthermore, although a constitutively active Gα13 enhanced the migration of control HeLa cells, the Gα13-induced cell migration was significantly suppressed in the JLP-depleted HeLa cells. … Taken together, these results suggest that JLP regulates cell migration through an interaction with Gα13. …
NAID 10024913756

Related Links

LSBM - インテグリン受容体と三量体型Gα13が直接相互作用して ...

2010.02.08 インテグリン受容体と三量体型Gα13が直接相互作用して細胞接着機能を制御する LSBM客員教授の小笹徹博士がイリノイ大学薬理学のXiaoping Du博士との共同研究で、インテグリン受容体と三量体型Gα13が直接相互作用して ...

Gα13 and Rho mediate endosomal trafficking of CXCR4 into ...

CXCR4 signaling activates heterotrimeric GTP-binding G proteins composed of α and βγ subunits, including members of the Gi, Gq, and G12/13 subfamilies (23, 25). While Gα13 has not previously been shown to regulate ...