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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/02/13 18:48:25」(JST)
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- 1. 乳癌におけるホルモン受容体：臨床的有用性および検査精度向上のためのガイドラインの推奨 hormone receptors in breast cancer clinical utility and guideline recommendations to improve test accuracy
- 2. Drug-induced thrombotic microangiopathy
- 3. Restless legs syndrome/Willis-Ekbom disease during pregnancy and lactation
- 4. Approach to the patient with suspected TTP, HUS, or other thrombotic microangiopathy (TMA)
- 5. 早期再分極 early repolarization
English Journal
- Ablative fractional laser treatment for hypertrophic scars: comparison between Er:YAG and CO2 fractional lasers.
- Choi JE1, Oh GN, Kim JY, Seo SH, Ahn HH, Kye YC.Author information 1Department of Dermatology, College of Medicine, Korea University , Seoul , Korea.AbstractBACKGROUND: Nonablative fractional photothermolysis has been reported to show early promise in the treatment of hypertrophic scars, but there are few reports on ablative fractional photothermolysis for the treatment of hypertrophic scars.
- The Journal of dermatological treatment.J Dermatolog Treat.2014 Aug;25(4):299-303. doi: 10.3109/09546634.2013.782090. Epub 2013 May 31.
- BACKGROUND: Nonablative fractional photothermolysis has been reported to show early promise in the treatment of hypertrophic scars, but there are few reports on ablative fractional photothermolysis for the treatment of hypertrophic scars.AIM: To evaluate and compare the efficacy and safety of Er:YAG
- PMID 23621348
- Disturbance of endogenous hydrogen sulfide generation and endoplasmic reticulum stress in hippocampus are involved in homocysteine-induced defect in learning and memory of rats.
- Li MH1, Tang JP1, Zhang P2, Li X3, Wang CY4, Wei HJ5, Yang XF2, Zou W6, Tang XQ7.Author information 1Department of Neurology, Nanhua Affiliated Hospital, University of South China, Hengyang, 421001 Hunan, PR China; Institute of Neuroscience, Medical College, University of South China, Hengyang, 421001 Hunan, PR China.2Department of Neurology, Nanhua Affiliated Hospital, University of South China, Hengyang, 421001 Hunan, PR China.3Department of Anesthesiology, the First Affiliated Hospital, University of South China, Hengyang, 421001 Hunan, PR China.4Department of Pathophysiology, Medical College, University of South China, Hengyang, 421001 Hunan, PR China.5Institute of Neuroscience, Medical College, University of South China, Hengyang, 421001 Hunan, PR China.6Department of Neurology, Nanhua Affiliated Hospital, University of South China, Hengyang, 421001 Hunan, PR China. Electronic address: zouw415@163.com.7Department of Neurology, Nanhua Affiliated Hospital, University of South China, Hengyang, 421001 Hunan, PR China; Institute of Neuroscience, Medical College, University of South China, Hengyang, 421001 Hunan, PR China. Electronic address: tangxq01001@foxmail.com.AbstractHomocysteine (Hcy) is a risk factor for Alzheimer's disease (AD). Hydrogen sulfide (H2S) acts as an endogenous neuromodulator and neuroprotectant. It has been shown that endoplasmic reticulum (ER) stress is involved in the pathological mechanisms of the learning and memory dysfunctions and that H2S exerts its neuroprotective role via suppressing ER stress. In the present work, we explored the effects of intracerebroventricular injection of Hcy on the formation of learning and memory, the generation of endogenous H2S, and the expression of ER stress in the hippocampus of rats. We found that intracerebroventricular injection of Hcy in rats leads to learning and memory dysfunctions in the Morris water maze and novel of object recognition test and decreases in the expression of cystathionine-β-synthase, the major enzyme responsible for endogenous H2S generation, and the generation of endogenous H2S in the hippocampus of rats. We also showed that exposure of Hcy could up-regulate the expressions of glucose-regulated protein 78 (GRP78), CHOP, and cleaved caspase-12, which are the major mark proteins of ER stress, in the hippocampus of rats. Taken together, these results suggest that the disturbance of hippocampal endogenous H2S generation and the increase in ER stress in the hippocampus are related to Hcy-induced defect in learning and memory.
- Behavioural brain research.Behav Brain Res.2014 Apr 1;262:35-41. doi: 10.1016/j.bbr.2014.01.001. Epub 2014 Jan 11.
- Homocysteine (Hcy) is a risk factor for Alzheimer's disease (AD). Hydrogen sulfide (H2S) acts as an endogenous neuromodulator and neuroprotectant. It has been shown that endoplasmic reticulum (ER) stress is involved in the pathological mechanisms of the learning and memory dysfunctions and that H2S
- PMID 24423987
- The endoplasmic reticulum-mitochondria connection: One touch, multiple functions.
- Marchi S1, Patergnani S1, Pinton P2.Author information 1Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Interdisciplinary Center for the Study of Inflammation (ICSI), Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.2Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Interdisciplinary Center for the Study of Inflammation (ICSI), Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy. Electronic address: pnp@unife.it.AbstractThe endoplasmic reticulum (ER) and mitochondria are tubular organelles with a characteristic "network structure" that facilitates the formation of interorganellar connections. The ER and mitochondria join together at multiple contact sites to form specific domains, termed mitochondria-ER associated membranes (MAMs), with distinct biochemical properties and a characteristic set of proteins. The functions of these two organelles are coordinated and executed at the ER-mitochondria interface, which provides a platform for the regulation of different processes. The roles played by the ER-mitochondria interface range from the coordination of calcium transfer to the regulation of mitochondrial fission and inflammasome formation as well as the provision of membranes for autophagy. The novel and unconventional processes that occur at the ER-mitochondria interface demonstrate its multifunctional and intrinsically dynamic nature. This article is part of a Special Issue entitled: Dynamic and ultrastructure of bioenergetic membranes and their components.
- Biochimica et biophysica acta.Biochim Biophys Acta.2014 Apr;1837(4):461-469. doi: 10.1016/j.bbabio.2013.10.015. Epub 2013 Nov 8.
- The endoplasmic reticulum (ER) and mitochondria are tubular organelles with a characteristic "network structure" that facilitates the formation of interorganellar connections. The ER and mitochondria join together at multiple contact sites to form specific domains, termed mitochondria-ER associated
- PMID 24211533
Japanese Journal
- Viral cell-to-cell movement requires formation of cortical punctate structures containing Red clover necrotic mosaic virus movement protein.
- Kaido Masanori,Funatsu Naoko,Tsuno Yasuko,Mise Kazuyuki,Okuno Tetsuro
- Virology 413(2), 205-215, 2011-05-10
- … Movement protein (MP) of Red clover necrotic mosaic virus (RCNMV) forms punctate structures on the cortical endoplasmic reticulum (ER) of Nicotiana benthamiana cells, which are associated with viral RNA1 replication (Kaido et al., Virology 395, 232-242. … We investigated the significance of ER-targeting by MP during virus movement from cell to cell, by analyzing the function of a series of MPs with varying length deletions at their C-terminus, either fused or not fused with green fluorescent protein (GFP). …
- NAID 120003018213
- CHOP deletion does not impact the development of diabetes but suppresses the early production of insulin autoantibody in the NOD mouse.
- Satoh T,Abiru Norio,Kobayashi M,Zhou H,Nakamura K,Kuriya Genpei,Nakamura H,Nagayama Y,Kawasaki Eiji,Yamasaki H,Yu L,Eisenbarth G S,Araki Eiichi,Mori M,Oyadomari Seiichi,Eguchi K
- Apoptosis : an international journal on programmed cell death 16(4), 438-448, 2011-04
- … C/EBP homologous protein (CHOP) has been proposed as a key transcription factor for endoplasmic reticulum (ER) stress-mediated β-cell death induced by inflammatory cytokines in vitro. … Expression of ER stress-associated genes was not significantly up-regulated in the islets from NOD.Chop (-/-) compared to those from wt mice or NOD-scid mice. …
- NAID 120002905522
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★リンクテーブル★
| リンク元 | 「トリプルネガティブ乳癌」「エストロゲン受容体」「小胞体」「緊急治療室」「救急室」 |
| 拡張検索 | 「MERRF症候群」「ERPF」「DEPO-TESTOSTERONE」 |
| 関連記事 | 「E」 |
「トリプルネガティブ乳癌」
「エストロゲン受容体」
- 英
- estrogen receptor, ER
- 関
- エストロゲン
- 核内受容体
- ERα：Chr6.
- ERβ：Chr14.
- ホモ二量体 or ヘテロ二量体を形成
「小胞体」
「緊急治療室」
- 英
- emergency room、ER
- 関
- 小胞体、救急室、救急治療室
「救急室」
- 英
- emergency room, ER
- 関
- 緊急治療室、救急治療室
「MERRF症候群」
「ERPF」
[★] 有効腎血漿流量 有効腎血循環量 effective renal plasma flow
「DEPO-TESTOSTERONE」
「E」