デュークス分類
WordNet
- restriction imposed by the government on documents or weapons that are available only to certain authorized people
- a group of people or things arranged by class or category (同)categorization, categorisation
- the basic cognitive process of arranging into classes or categories (同)categorization, categorisation, sorting
PrepTutorEJDIC
- 〈U〉〈C〉分類[作業];分類法;分類結果 / 〈U〉(生物学上の)分類
- 握りこぶし,げんこつ
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/04/11 00:28:27」(JST)
[Wiki en表示]
In 1932 the British pathologist Cuthbert Dukes (1890-1977) devised a famous classification system for colorectal cancer.[1] Several different forms of the Dukes classification were developed.[2][3] However, this system has largely been replaced by the more detailed TNM staging system and is no longer recommended for use in clinical practice.[4]
Dukes' A: Invasion into but not through the bowel wall(90% 5-y survival)
Dukes' B: Invasion through the bowel wall but not involving lymph nodes(70% 5-y survival)
Dukes' C: Involvement of lymph nodes(30% 5-y survival)
Dukes' D: Widespread metastases
An adaptation by the Americans Astler and Coller in 1954 further divided stages B and C[5]
Stage A: Limited to mucosa
Stage B1: Extending into muscularis propria but not penetrating through it; nodes not involved
Stage B2: Penetrating through muscularis propria; nodes not involved
Stage C1: Extending into muscularis propria but not penetrating through it. Nodes involved
Stage C2: Penetrating through muscularis propria. Nodes involved
Stage D: Distant metastatic spread
The stage gives valuable information for the prognosis and management of the particular cancer.
References
- ^ Who Named It, showing correct grammatical usage
- ^ Kyriakos M: The President cancer, the Dukes classification, and confusion, Arch Pathol Lab Med 109:1063, 1985
- ^ Dukes CE. The classification of cancer of the rectum. Journal of Pathological Bacteriology 1932;35:323
- ^ AJCC (American Joint Committee on Cancer) Cancer Staging Manual, 7th ed, Edge, SB, Byrd, DR, Compton, CC, et al (Eds), Springer, New York 2010. p 143.
- ^ Astler VB, Coller FA: The prognostic significance of direct extension of carcinoma of the colon and rectum. Ann Surg 139:846, 1954
UpToDate Contents
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English Journal
- Plasminogen Activation System in Rectal Adenocarcinoma.
- Razik E1, Kobierzycki C2, Grzegrzolka J3, Podhorska-Okolow M3, Drag-Zalesinska M3, Zabel M4, Dziegiel P5.
- Anticancer research.Anticancer Res.2015 Nov;35(11):6009-15.
- BACKGROUND: The purpose of the present study was to determine the extent of expression of proteins that are the elements of the plasminogen activation system, i.e. urokinase plasminogen activator (uPA), receptor of uPA (uPAR), plasminogen activating inhibitor-1 (PAI-1) and tissue plasminogen activat
- PMID 26504024
- Colorectal carcinoma in the first decade of life: a systematic review.
- da Costa Vieira RA1, Tramonte MS, Lopes LF.
- International journal of colorectal disease.Int J Colorectal Dis.2015 Aug;30(8):1001-6. doi: 10.1007/s00384-015-2202-1. Epub 2015 Apr 28.
- PURPOSE: The aim of this study is to better understand the main aspects related to colorectal carcinoma diagnosed in the first 10 years of life, through a systematic review.METHODS: We carried out a bibliographic search in PubMed and LILACS, focusing on identifying publications or case reports abou
- PMID 25916603
- Colorectal cancer: the first neoplasia found to be under immunosurveillance and the last one to respond to immunotherapy?
- Kroemer G1, Galluzzi L2, Zitvogel L3, Fridman WH4.
- Oncoimmunology.Oncoimmunology.2015 Jun 5;4(7):e1058597. eCollection 2015.
- The first study demonstrating that human colorectal carcinoma (CRC) is under robust immunosurveillance was published a decade ago. Today, it is clear that CRC patients with Stage III lesions abundantly infiltrated by effector memory T cells have a better prognosis than subjects with Stage I neoplasm
- PMID 26140250
Japanese Journal
- Dukes C 結腸・直腸S状部癌のリンパ節転移率と予後からみた新しいリンパ節転移程度分類の試み
- 横溝 肇,吉松 和彦,大谷 泰介,大澤 岳史,中山 真緒,矢野 有紀,松本 敦夫,藤本 崇司,梅原 有弘,小川 健治
- 日本外科系連合学会誌 36(1), 1-5, 2011-02-28
- NAID 10029365305
- Ｄｕｋｅｓ Ｃ結腸・直腸Ｓ状部癌のリンパ節転移率と予後からみた新しいリンパ節転移程度分類の試み
- 横溝 肇,吉松 和彦,大谷 泰介,大澤 岳史,中山 真緒,矢野 有紀,松本 敦夫,藤本 崇司,梅原 有弘,小川 健治
- 日本外科系連合学会誌 36(1), 1-5, 2011
- … リンパ節転移率がリンパ節転移程度分類の指標となり得るか検討した．当科で根治度Ａ手術を行ったDukes C初発結腸・直腸Ｓ状部癌149例を対象とし，リンパ節転移率と予後の関連につき検討した．リンパ節転移率を各10％，15％，20％，25％，30％で区分して予後をみると，転移率20％で区分した場合に予後に最も大きな差を認めた．転移率20％未満/以上とpN1/pN2 or pN3との組み合わせで４群に細分類すると，転移率20％未満 …
- NAID 130004514975
- Study of interleukin-6 in the spread of colorectal cancer: the diagnostic significance of IL-6.
- Ashizawa Tatsuto,Okada Ryosuke,Suzuki Yoshiaki,Takagi Makoto,Yamazaki Tatsuyuki,Sumi Tetsuo,Aoki Toshiaki,Aoki Tatsuya
- Acta Medica Okayama 60(6), 325-330, 2006-12
- … We investigated the diagnostic significance of IL-6 for lymph node metastasis and/or hepatic metastasis from colorectal cancer in 65 patients and evaluated the contributions of 8 factors (IL-6, HGF, IL-1beta, TNF-alpha, TGF-beta1, ELAM-1, ICAM-1, VCAM-1) toward Dukes.s classification of 53 patients. … IL-6, HGF, and ELAM-1 were very useful for distinguishing among Dukes.s A/B group, C group, and D group. …
- NAID 120002304962
Related Links
- Dukes' classification, a staging system for colorectal tumors, from A to D, according to the degree of tissue invasion and metastasis. A Dukes' A tumor is one that is confined to the mucosa and submucosa. A B tumor is one that has ...
- Dukes classification (d ks) n. A classification into three stages of the extent of spread of operable carcinoma of the large intestine. Dukes clas·si·fi·ca·tion (dūks), a classification of the extent of invasion of a resected adenocarcinoma ...
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