DNA-formamidopyrimidine glycosylase

DNAホルムアミドピリミジングリコシラーゼ

関

formamidopyrimidine-DNA glycosylase

WordNet

1. the 4th letter of the Roman alphabet (同)d

PrepTutorEJDIC

1. deuteriumの化学記号
2. deoxyribonucleic acidディオキシリボ核酸

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/06 09:51:52」(JST)

wiki en

[Wiki en表示]

DNA-formamidopyrimidine glycosylase
Identifiers
EC number	3.2.2.23
CAS number	78783-53-6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

DNA-formamidopyrimidine glycosylase (EC 3.2.2.23, Fapy-DNA glycosylase, deoxyribonucleate glycosidase, 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase, 2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase, formamidopyrimidine-DNA glycosylase, DNA-formamidopyrimidine glycosidase, Fpg protein) is an enzyme with system name DNA glycohydrolase (2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing). This enzyme catalyses the following chemical reaction

Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine

This enzyme participates in processes leading to recovery from mutagenesis and/or cell death by alkylating agents.

References

External links

• DNA-formamidopyrimidine glycosylase at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. DNAによる親子鑑定 parentage testing using dna
• 2. 次世代DNAシークエンシングの原理および臨床応用 principles and clinical applications of next generation dna sequencing
• 3. Prenatal screening for Down syndrome using cell-free DNA
• 4. T-B-NK+ SCID：病因および遺伝学 t b nk scid pathogenesis and genetics
• 5. サイトメガロウイルス感染の診断へのアプローチ approach to the diagnosis of cytomegalovirus infection

English Journal

• Comparison of the Genotoxic Effects Induced by 50 Hz Extremely Low-Frequency Electromagnetic Fields and 1800 MHz Radiofrequency Electromagnetic Fields in GC-2 Cells.

• Duan W1, Liu C, Zhang L, He M, Xu S, Chen C, Pi H, Gao P, Zhang Y, Zhong M, Yu Z, Zhou Z.
• Radiation research.Radiat Res.2015 Feb 17. [Epub ahead of print]
• Extremely low-frequency electromagnetic fields (ELF-EMF) and radiofrequency electromagnetic fields (RF-EMF) have been considered to be possibly carcinogenic to humans. However, their genotoxic effects remain controversial. To make experiments controllable and results comparable, we standardized expo
• PMID 25688995

• Induction of DNA base damage and strand breaks in peripheral erythrocytes and the underlying mechanism in goldfish (Carassius auratus) exposed to monocrotophos.

• Zhao F1, Wang B, Zhang X, Tian H, Wang W, Ru S.
• Fish physiology and biochemistry.Fish Physiol Biochem.2015 Feb 10. [Epub ahead of print]
• Using goldfish (Carassius auratus) as the model animal, the present study revealed the types of the DNA damage induced by monocrotophos, a highly toxic organophosphorus pesticide, and explored the mechanism underlying the DNA-damaging effect of this pesticide. Results of the alkaline comet assay sho
• PMID 25666866

• Antioxidant and anti-genotoxic properties of cerium oxide nanoparticles in a pulmonary-like cell system.

• Rubio L1, Annangi B, Vila L, Hernández A, Marcos R.
• Archives of toxicology.Arch Toxicol.2015 Jan 25. [Epub ahead of print]
• Cerium oxide nanoparticles (CeO2-NP) present two different oxidation states what can suppose an auto-regenerative redox cycle. Potential applications of CeO2-NP to quench reactive oxygen species (ROS) in biological systems are currently being investigated. In this context, CeO2-NP may represent a no
• PMID 25618551

Related Links

• Formamidopyrimidine DNA glycosylase - Wikipedia, the free ...

Formamidopyrimidine DNA glycosylase (FPG) is a base excision repair enzyme which recognizes and removes a wide range of oxidized purines from correspondingly damaged DNA.It was discovered by Zimbabwean scientist Christopher J.

• Structure of Formamidopyrimidine-DNA Glycosylase Covalently ...

31 May 2002 ... Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidized purines from damaged DNA. The Schiff base intermediate formed during this reaction betweenEscherichia coli Fpg and DNA was ...

---

★リンクテーブル★

リンク元	「DNAホルムアミドピリミジングリコシラーゼ」「formamidopyrimidine-DNA glycosylase」
関連記事	「D」「DNA」

「DNAホルムアミドピリミジングリコシラーゼ」

　　[★]

英

DNA-formamidopyrimidine glycosylase

関

ホルムアミドピリミジンDNAグリコシラーゼ

「formamidopyrimidine-DNA glycosylase」

　　[★]

ホルムアミドピリミジンDNAグリコシラーゼ

関

DNA-formamidopyrimidine glycosylase

「D」

　　[★]

• アスパラギン酸
• ジヒドロウリジン
• 遠位の distal,
• うつ病 depression
• 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)

　 　

「DNA」

　　[★]

英

deoxyribonucleic acid

同

デオキシリボ核酸

関

リボ核酸 RNA