WordNet

any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Nucleofection-Mediated α1,3-galactosyltransferase Gene Inactivation and Membrane Cofactor Protein Expression for Pig-to-Primate Xenotransplantation.

Ko N, Lee JW, Hwang SS, Kim B, Ock SA, Lee SS, Im GS, Kang MJ, Park JK, Jong Oh S, Bong Oh K.Sourcea Animal Biotechnology Division , National Institute of Animal Science , RDA , Suwon , South Korea.
Animal biotechnology.Anim Biotechnol.2013 Oct 2;24(4):253-67. doi: 10.1080/10495398.2012.752741.
Xenotransplantation of pig organs into primates leads to hyperacute rejection (HAR). Functional ablation of the pig α 1,3-galactosyltransferase (GalT) gene, which abrogates expression of the Gal α 1-3Gal β 1-4GlcNAc-R (Gal) antigen, which inhibits HAR. However, antigens other than Gal may induce
PMID 23947662

Does dysregulated complement activation contribute to haemolytic uraemic syndrome secondary to Streptococcus pneumoniae?

Gilbert RD, Nagra A, Haq MR.SourceRegional Paediatric Nephro-Urology Unit, University Hospital Southampton, Tremona Road, Southampton SO16 6YD, United Kingdom. Electronic address: Rodney.Gilbert@uhs.nhs.uk.
Medical hypotheses.Med Hypotheses.2013 Sep;81(3):400-3. doi: 10.1016/j.mehy.2013.05.030. Epub 2013 Jun 17.
We describe two patients with haemolytic uraemic syndrome (HUS) associated with invasive Streptococcus pneumoniae infection. Both patients had transiently reduced serum concentrations of complement C3. One had reduced expression of CD46 and never recovered renal function. No constitutive defect in r
PMID 23786906

Measles virus expressed Helicobacter pylori neutrophil-activating protein significantly enhances the immunogenicity of poor immunogens.

Iankov ID, Federspiel MJ, Galanis E.SourceDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA. Electronic address: Iankov.Ianko@mayo.edu.
Vaccine.Vaccine.2013 Aug 12. pii: S0264-410X(13)01083-9. doi: 10.1016/j.vaccine.2013.07.085. [Epub ahead of print]
Helicobacter pylori neutrophil-activating protein (NAP) is a toll-like receptor 2 (TLR2) agonist and potent immunomodulator inducing Th1-type immune response. Here we present data about characterization of the humoral immune response against NAP-tagged antigens, encoded by attenuated measles virus (
PMID 23948230

Purification and functional properties of soluble forms of membrane cofactor protein (CD46) of complement: identification of forms increased in cancer patients' sera

Glycosyl-phosphatidylinositol-anchored and transmembrane forms of CD46 display similar measles virus receptor properties:virus binding, fusion, and replication, down-regulation by hemagglutinin;and virus uptake and endocytosis for antigen presentation by major histocompatibility complex class II molecules