B cell antigen receptor

表面免疫グロブリン。B細胞抗原受容体

WordNet

1. small room in which a monk or nun lives (同)cubicle
2. a device that delivers an electric current as the result of a chemical reaction (同)electric cell
3. a room where a prisoner is kept (同)jail cell, prison cell
4. (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
5. any small compartment; "the cells of a honeycomb"
6. a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
7. the 2nd letter of the Roman alphabet (同)b
8. the blood group whose red cells carry the B antigen (同)type_B, group B
9. any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
10. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response

PrepTutorEJDIC

1. (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
2. 抗原(生物の体内にはいって免疫体を作る物質)
3. =sense organ / 受信装置

UpToDate Contents

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• 1. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
• 2. 体液性免疫応答 the humoral immune response
• 3. 非ホジキンリンパ腫の病理の概要 overview of the pathobiology of the non hodgkin lymphomas
• 4. リウマチ性疾患における生物学的製剤の概要 overview of biologic agents in the rheumatic diseases
• 5. 胎児および新生児における免疫細胞の発達 the development of immune cells in the fetus and neonate

English Journal

• Distinct processing of the pre-B cell receptor and the B cell receptor.

• Cohen S, Haimovich J, Hollander N.SourceDepartment of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
• Molecular immunology.Mol Immunol.2013 Jun;54(2):115-21. doi: 10.1016/j.molimm.2012.11.004. Epub 2012 Dec 23.
• It has been recently demonstrated that while oligosaccharide moieties of μ heavy chains in the B-cell receptor (BCR) are of the complex type as expected, those of the pre-BCR on the surface of pre-B cells contain oligosaccharide moieties of the high-mannose type only. This is unique, because high-m
• PMID 23267849

• miR-155: an ancient regulator of the immune system.

• Vigorito E, Kohlhaas S, Lu D, Leyland R.SourceLaboratory of Lymphocyte Signalling and Development, The Babraham Institute, Babraham Research Campus, Cambridge, UK.
• Immunological reviews.Immunol Rev.2013 May;253(1):146-57. doi: 10.1111/imr.12057.
• MicroRNAs (miRNAs) are a newly recognized class of regulatory genes which repress the expression of protein-coding genes. Numerous studies have uncovered a complex role for miRNAs regulating many aspects of a variety of cellular processes including cell growth, differentiation, and lineage commitmen
• PMID 23550644

• Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2.

• Strefford JC, Sutton LA, Baliakas P, Agathangelidis A, Malčíková J, Plevova K, Scarfó L, Davis Z, Stalika E, Cortese D, Cahill N, Pedersen LB, di Celle PF, Tzenou T, Geisler C, Panagiotidis P, Langerak AW, Chiorazzi N, Pospisilova S, Oscier D, Davi F, Belessi C, Mansouri L, Ghia P, Stamatopoulos K, Rosenquist R.SourceCancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
• Leukemia.Leukemia.2013 Apr 5. doi: 10.1038/leu.2013.98. [Epub ahead of print]
• Recent studies have revealed recurrent mutations of the NOTCH1, SF3B1 and BIRC3 genes in chronic lymphocytic leukemia (CLL), especially among aggressive, chemorefractory cases. Nevertheless, it is currently unknown whether their presence may differ in subsets of patients carrying stereotyped B-cell
• PMID 23558524

Japanese Journal

• がん免疫細胞療法の新しい展開 : overview (第4回 がん新薬開発合同シンポジウム 日本からのグローバルエビデンス発信を目指して : 今取り組むべき課題)

• 中面 哲也
• 腫瘍内科 = Clinical oncology 15(3), 310-314, 2015-03
• NAID 40020398624

• 多発性骨髄腫におけるSLAMファミリー分子の機能とそれらを標的としたキメラ抗原受容体遺伝子改変T細胞免疫療法

• 田村 秀人
• 血液内科 70(2), 211-217, 2015-02
• NAID 40020385129

• 制御性B細胞の分化誘導因子と作用機序に関する検討

• 吉崎 歩,TEDDER Thomas F.
• 日本臨床免疫学会会誌 38(1), 57-64, 2015
•   近年，B細胞の働きは単に抗体を産生するのみではなく，抗原提示や炎症性サイトカインの産生，T細胞をはじめとする免疫細胞の活性化誘導など，炎症反応において中心的な役割を果たすことが知られるようになってきた．B細胞は炎症反応を誘導するだけでなく，活性化した炎症細胞に作用することで，免疫抑制作用をも発揮することが知られているが，著者らのグループでは，この中でも特にinterleukin（IL）-10を …
• NAID 130004875952

Related Links

• B cell antigen receptor signaling 101 - ScienceDirect.com ...

All cells continually survey their environment and make decisions based on cues encountered. This requires specific receptors that detect such cues, then transd ... Fig. 1. B cell antigen receptor signal transduction cascade. Signal ...

• B-Cell Antigen Receptor - ScienceDirect.com | Science ...

B-Cell Antigen Receptor T.M. Yankee Author Vitae University of Kansas Medical Center, Kansas City, KS, USA Current as of 1 May 2014 1 May 2014 Available online 22 ... Abstract B cells must recognize and respond to antigens ...

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★リンクテーブル★

リンク元	「表面免疫グロブリン」「B細胞抗原受容体」
拡張検索	「B-cell antigen receptor」
関連記事	「B」「antigen receptor」「cell」

「表面免疫グロブリン」

　　[★]

英

surface immunoglobulin, SIG, sIg

同

細胞表面免疫グロブリン cell-surface immunoglobulin、B細胞抗原受容体 B cell antigen receptor、膜型免疫グロブリン membrane immunoglobulin

関

免疫グロブリン

「B細胞抗原受容体」

　　[★]

英

B-cell antigen receptor, B cell antigen receptor

関

B細胞抗原レセプター、表面免疫グロブリン

「B-cell antigen receptor」

　　[★]

• B細胞抗原受容体、B細胞抗原レセプター

「B」

　　[★]

• 気管分岐部下緑
• 補体のalternative pathwayに関わる蛋白質

• Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

　 　

「antigen receptor」

　　[★]

• 抗原受容体、抗原レセプター

「cell」

　　[★] 細胞