WordNet

any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response

PrepTutorEJDIC

抗体,免疫体,抗毒素

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1. 重症筋無力症の診断 diagnosis of myasthenia gravis
2. 重症筋無力症の病因 pathogenesis of myasthenia gravis
3. 重症筋無力症に対する胸腺摘出術 thymectomy for myasthenia gravis
4. 眼筋型重症筋無力症 ocular myasthenia gravis
5. 重症筋無力症の治療 treatment of myasthenia gravis

English Journal

B cells produce less IL-10, IL-6 and TNF-α in myasthenia gravis.

Yilmaz V1, Oflazer P, Aysal F, Parman YG, Direskeneli H, Deymeer F, Saruhan-Direskeneli G.
Autoimmunity.Autoimmunity.2015 Jun;48(4):201-7. doi: 10.3109/08916934.2014.992517. Epub 2014 Dec 18.
B cells from myasthenia gravis (MG) patients with autoantibodies (Aab) against acetylcholine receptor (AChR), muscle-specific kinase (MuSK) or with no detectable Aab were investigated as cytokine producing cells in this study. B cells were evaluated for memory phenotypes and expressions of IL-10, IL
PMID 25518708

Serum high mobility group box 1 is upregulated in myasthenia gravis.

Uzawa A1, Kawaguchi N2, Kanai T1, Himuro K1, Kuwabara S1.
Journal of neurology, neurosurgery, and psychiatry.J Neurol Neurosurg Psychiatry.2015 Jun;86(6):695-7. doi: 10.1136/jnnp-2014-309232. Epub 2014 Oct 24.
OBJECTIVE: High mobility group box 1 (HMGB1) functions as an inflammatory mediator and is implicated in the pathogenesis of various autoimmune diseases. Our primary aim is to determine whether HMGB1 is involved in the pathogenesis of myasthenia gravis (MG).METHODS: Serum HMGB1 levels of 60 patients
PMID 25344065
PMID 25964166

Japanese Journal

抗アセチルコリンレセプター抗体高値を伴った赤芽球癆合併胸腺腫の1例

日本臨床外科学会雑誌 76(5), 975-980, 2015
NAID 130005110771

アセチルコリン受容体抗体陰性の重症筋無力症に認められる自己抗体 (神経・筋疾患の最近の進歩)

臨床病理 : 日本臨床検査医学会誌 62(3), 255-260, 2014-03
NAID 40020057100

Clinical features and treatment status of adult myasthenia gravis in Japan

Clinical and Experimental Neuroimmunology 5(1), 84-91, 2014-02
NAID 120005457103

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抗アセチルコリンレセプター抗体(抗AChR抗体)

神経筋接合部の後シナプス膜上に局在しており,神経伝達物質であるアセチルコリンに応答する受容体で,筋収縮を作動させる役割を持つ。抗アセチルコリンレセプター抗体(抗AChR抗体)については,Lindstromらが1976年,重症筋無力症(MG)患者 ...

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