WordNet

of or relating to the pituitary gland; "pituitary hormone"
the master gland of the endocrine system; located at the base of the brain (同)pituitary_gland, pituitary body, hypophysis
a benign epithelial tumor of glandular origin

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1. クッシング症候群の治療の概要 overview of the treatment of cushings syndrome
2. クッシング症候群の診断 establishing the diagnosis of cushings syndrome
3. クッシング症候群の疫学および臨床症状 epidemiology and clinical manifestations of cushings syndrome
4. クッシング病の一次治療：経蝶形骨洞手術および下垂体照射 primary therapy of cushings disease transsphenoidal surgery and pituitary irradiation
5. クッシング症候群の原因および病態生理 causes and pathophysiology of cushings syndrome

Human Kallikrein 10 Expression in Surgically Removed Human Pituitary Corticotroph Adenomas: An Immunohistochemical Study.

Di Meo A1, Rotondo F, Kovacs K, Cusimano MD, Syro LV, Di Ieva A, Diamandis EP, Yousef GM.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry.Appl Immunohistochem Mol Morphol.2014 Dec 16. [Epub ahead of print]
Human kallikrein 10 (hk10), a secreted serine protease, was reported to function as a tumor suppressor. hK10 immunoexpression has been demonstrated in lactrotrophs and corticotrophs of the nontumorous human adenohypophysis. In the present study, for the first time we report hK10 immunoexpression in
PMID 25517869

Downregulation of Insulin-like growth factor binding protein 6 is associated with ACTH-secreting pituitary adenoma growth.

Yang Y1, Sheng M, Huang F, Bu D, Liu X, Yao Y, Dai C, Sun B, Zhu J, Jiao Y, Wei Z, Zhu H, Lu L, Zhao Y, Jiang C, Wang R.
Pituitary.Pituitary.2014 Dec;17(6):505-13. doi: 10.1007/s11102-013-0535-8.
BACKGROUND: Adrenocorticotrophic hormone (ACTH)-dependent Cushing's syndrome, called Cushing disease, is caused by a corticotroph tumor of the pituitary gland. Insulin-like growth factor binding protein 6 (IGFBP6), which regulates insulin-like growth factor (IGF) activity and inhibits several IGF2-d
PMID 24379119

Duan K1, Gomez Hernandez K2, Mete O3.
Journal of clinical pathology.J Clin Pathol.2014 Nov 25. pii: jclinpath-2014-202612. doi: 10.1136/jclinpath-2014-202612. [Epub ahead of print]
Endogenous Cushing's syndrome is a rare endocrine disorder that incurs significant cardiovascular morbidity and mortality, due to glucocorticoid excess. It comprises adrenal (20%) and non-adrenal (80%) aetiologies. While the majority of cases are attributed to pituitary or ectopic corticotropin (ACT
PMID 25425660

富永篤,木下康之,碓井智,栗栖薫
脳神経外科ジャーナル 22(2), 101-108, 2013
非機能性下垂体腺腫に対する治療の第一選択は手術であるが, 機能性下垂体腺腫では有効な薬物療法があり, 手術が必ずしも第一選択ではない. プロラクチノーマではdopamine agonistによる治療がすでに第一選択となっている. ただ, プロラクチン正常化率は高いが治癒率は必ずしも高くない. 先端巨大症ではsomatostatin analogやpegvisomantなど有効率が高い薬剤がある …
NAID 130003379591

肥塚直美,高野加寿恵
脳神経外科ジャーナル 18(5), 342-346, 2009-05-20
… 後の対応に配慮が必要である.ホルモン産生下垂体腺腫を有する挙児希望女性を診療する際には,妊娠による下垂体の腫大および下垂体ホルモン分泌動態の変化を十分に理解し対応することが重要である.本稿では挙児希望女性に発生したホルモン産生下垂体腺腫のうち,プロラクチン(PRL)産生腺腫,成長ホルモン(GH)産生腺腫,副腎皮質刺激ホルモン(ACTH)産生腺腫を取り上げ,妊娠前,妊娠中および分娩後の対応について概説した. …
NAID 110007227562