UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 抗Ro/SSA抗体および抗La/SSB抗体の抗原抗体系the anti ro ssa and anti la ssb antigen antibody systems [show details]
… Anti-Ro antibodies have also been detected in 6 to 12 percent of patients with RA . No difference was seen between the clinical presentations of anti-Ro antibody-positive versus anti-Ro antibody-negative …
2. シェーグレン症候群の診断および分類diagnosis and classification of sjogrens syndrome [show details]
…of Sjogren syndrome (SS) in these patients is necessarily supported by a positive test for anti-Ro/SSA antibodies and/or a labial salivary gland biopsy showing focal lymphocytic sialadenitis with a focus …
3. 全身性エリテマトーデスを有する女性における妊娠pregnancy in women with systemic lupus erythematosus [show details]
…block, which occurs in approximately 2 percent of children born to primigravid women with anti-Ro/SSA antibodies . In women who have had a child with congenital complete heart block, the risk of complete…
4. 新生児ループス：疫学、発症機序、臨床症状、診断neonatal lupus epidemiology pathogenesis clinical manifestations and diagnosis [show details]
…develop autoimmune disease (more commonly Sjogren syndrome than SLE) . The prevalence of anti-Ro/SSA antibodies was initially reported as 0.2 to 0.72 percent in female blood donors and, more recently …
5. シェーグレン症候群の病因pathogenesis of sjogrens syndrome [show details]
…individuals indicates that autoantibodies alone are insufficient for induction of disease . Anti-Ro/SSA antibodies are predominantly of the immunoglobulin G1 (IgG1) subclass and recognize two distinct proteins …

Japanese Journal

抗Ro抗体と新生児心ブロック (特集膠原病に伴う循環器疾患)

山西愼吾,伊藤保彦
呼吸と循環 63(11), 1057-1062, 2015-11
NAID 40020628989

膠原病の考え方診かたの進歩膠原病の臓器病変・診かたの進歩心・血管病変

東條毅,秋谷久美子
日本内科学会雑誌 86(8), 1375-1380, 1997-08-10
… 検例での頻度は高いが,進行例以外は臨床的な心症状に気付かれぬ場合が少なくなかった.各種の画像診断法の進歩でその早期診断が可能となり,より正確な頻度が把握できるようになった.これとともにその発症機序に関する知見も進み,抗リン脂質抗体や抗Ro抗体などの臨床的意義が認められてきている.他方,副腎皮質ステロイド薬の長期服用例の増加により,二次的な心・血管病変の新たな増加が懸念されるようになった. …
NAID 10005525187