ビタミンB12依存性メチルマロン酸血症
WordNet
- relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
- addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
- contingent on something else (同)dependant, qualified
- (of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
- any of a group of organic substances essential in small quantities to normal metabolism
- a blood disorder characterized by an increased concentration of hydrogen ions in the blood (which falls below 7 on the pH scale)
PrepTutorEJDIC
- 『頼っている』,依存している,従属している / 扶養される人(家族)
- 『ビタミン』,栄養素(身体の喜常な機能を維持するために少量ながら必要な有機化合物)
- black(鉛筆の軟度を示す;硬度は『H』(=hard)で表す) / boronの化学記号
UpToDate Contents
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English Journal
- Metabolic network rewiring of propionate flux compensates vitamin B12 deficiency in C. elegans.
- Watson E1,2, Olin-Sandoval V3, Hoy MJ1,2, Li CH1,2, Louisse T1,2, Yao V4,5, Mori A1,2, Holdorf AD1,2, Troyanskaya OG4,5,6, Ralser M3,7, Walhout AJ1,2.
- eLife.Elife.2016 Jul 6;5. pii: e17670. doi: 10.7554/eLife.17670.
- Metabolic network rewiring is the rerouting of metabolism through the use of alternate enzymes to adjust pathway flux and accomplish specific anabolic or catabolic objectives. Here, we report the first characterization of two parallel pathways for the breakdown of the short chain fatty acid propiona
- PMID 27383050
- The proteome of methylmalonic acidemia (MMA): the elucidation of altered pathways in patient livers.
- Caterino M1, Chandler RJ2, Sloan JL2, Dorko K3, Cusmano-Ozog K4, Ingenito L5, Strom SC6, Imperlini E5, Scolamiero E5, Venditti CP2, Ruoppolo M1.
- Molecular bioSystems.Mol Biosyst.2016 Feb;12(2):566-74. doi: 10.1039/c5mb00736d.
- Methylmalonic acidemia (MMA) is a heterogeneous and severe autosomal recessive inborn error of metabolism most commonly caused by the deficient activity of the vitamin B12 dependent enzyme, methylmalonyl-CoA mutase (MUT). The main treatment for MMA patients is the dietary restriction of propiogenic
- PMID 26672496
- Methylmalonic acidemia: a megamitochondrial disorder affecting the kidney.
- Zsengellér ZK1, Aljinovic N, Teot LA, Korson M, Rodig N, Sloan JL, Venditti CP, Berry GT, Rosen S.
- Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2014 Nov;29(11):2139-46. doi: 10.1007/s00467-014-2847-y. Epub 2014 May 28.
- BACKGROUND: Classical (or isolated) methylmalonic acidemia (MMA) is a heterogeneous inborn error of metabolism most typically caused by mutations in the vitamin B12-dependent enzyme methylmalonyl-CoA mutase (MUT). With the improved survival of individuals with MMA, chronic kidney disease has become
- PMID 24865477
Related Links
- Vitamin B12-responsive methylmalonic acidemia ( Adenosylcobalamin deficiency Vitamin B12 responsive methylmalonic aciduria ) Orphanumber: 28 It's a disease Unknown which normally occurs either in the neonatal PHASE ...
- http://www.orpha.net/data/patho/Pro/en/Emergency_BIMDG_MethylmalonicAcidemia-enPro1263.pdf :: Methylmalonic acidemia Diseases: Methylmalonic acidemia, vitamin B12 unresponsive Methylmalonic acidemia, vitamin B12 ...
★リンクテーブル★
[★]
- 英
- vitamin B12-dependent methylmalonic acidemia
- 同
- ビタミンB12反応性メチルマロン酸血症
[★]
- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
[★]
- 関
- depend、dependence、dependency、dependently
[★]
- 関
- methylmalonic acid
[★]
ビタミンB12 cobalamin
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メチルマロン酸血症