WordNet

of or relating to or involving vesicles; "normal vesicular breathing"

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小嚢の小胞の,小嚢(小胞)状の

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1. 人身売買：医療現場での発見および評価human trafficking identification and evaluation in the health care setting [show details]
… for later sexual exploitation. In a survey study of nearly 200 female survivors of sex trafficking, approximately 60 percent reported physical and/or sexual abuse prior to being trafficked . However, while …
2. 高齢者の虐待：虐待、放置、および経済的搾取elder mistreatment abuse neglect and financial exploitation [show details]
…mistreatment – Elder mistreatment includes abuse, neglect, and financial exploitation as defined in this article. Financial exploitation – The nonconsensual appropriation of an elderly person resources, for …
3. ハンチントン病：遺伝学と病因huntington disease genetics and pathogenesis [show details]
…functions for wild-type huntingtin include roles in the regulation of ciliogenesis, protein trafficking, vesicular transport and anchoring to the cytoskeleton, endocytosis, and postsynaptic signaling . In …
4. 糸球体足細胞のバイオロジーbiology of glomerular podocytes [show details]
…example, podocyte deficiency in the vacuolar protein sorting-34 (Vps34), which controls several vesicular trafficking processes, leads to podocyte vacuolization and defective autophagy, early proteinuria, glomerular…
5. 新生児や乳児（生後6か月未満）に生じる慢性下痢症へのアプローチapproach to chronic diarrhea in neonates and young infants less than6 months [show details]
…hyperplasia or crypt hypoplasia; these findings may be seen in defects of enterocyte structure, vesicular trafficking, differentiation, and immune-mediated conditions. Specifically, villus blunting and apoptosis …

English Journal

Validity of the MPTP-Treated Mouse as a Model for Parkinson's Disease.

Klemann CJ1, Martens GJ1, Poelmans G1,2,3, Visser JE4,5,6.
Molecular neurobiology.Mol Neurobiol.2016 Apr;53(3):1625-36. doi: 10.1007/s12035-015-9103-8. Epub 2015 Feb 13.
Parkinson's disease (PD) is characterized by dopaminergic (DA) neuron death in the substantia nigra (SN) and subsequent striatal adaptations. Mice treated with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine (MPTP) are widely used as a model for PD. To assess the validity of the MPTP m
PMID 25676140

Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b.

Shao X1, Liu Y1,2,3, Yu Q1,2, Ding Z1, Qian W2,4, Zhang L1, Zhang J1, Jiang N2,5, Gui L1, Xu Z6, Hong Y7, Ma Y1, Wei Y1, Liu X4, Jiang C1,2, Zhu M4, Li H1, Li H4,8.
Cell research.Cell Res.2016 Mar 18. doi: 10.1038/cr.2016.34. [Epub ahead of print]
Numb is an endocytic protein that plays crucial roles in diverse cellular processes such as asymmetric cell division, cell migration and differentiation. However, the molecular mechanism by which Numb regulates endocytic trafficking is poorly understood. Here, we demonstrate that Numb is a docking r
PMID 26987402

Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes.

Kobayashi S1, Suzuki T2, Kawaguchi A3, Phongphaew W3, Yoshii K4, Iwano T5, Harada A6, Kariwa H4, Orba Y3, Sawa H7.
The Journal of biological chemistry.J Biol Chem.2016 Mar 18;291(12):6559-68. doi: 10.1074/jbc.M115.712760. Epub 2016 Jan 27.
West Nile virus (WNV) particles assemble at and bud into the endoplasmic reticulum (ER) and are secreted from infected cells through the secretory pathway. However, the host factor related to these steps is not fully understood. Rab proteins, belonging to the Ras superfamily, play essential roles in
PMID 26817838

Japanese Journal

Viroporin activity of the JC polyomavirus is regulated by interactions with the adaptor protein complex 3

Suzuki Tadaki,Orba Yasuko,Makino Yoshinori,Okada Yuki,Sunden Yuji,Hasegawa Hideki,Hall William W.,Sawa Hirofumi
Proceedings of the National Academy of Sciences of the United States of America 110(46), 18668-18673, 2013-11-12
… This interaction interrupts adaptor protein complex 3-mediated vesicular trafficking with suppression of the targeting of the protein to the lysosomal degradation pathway and instead permits the transport of agnoprotein to the cell surface with resulting membrane permeabilization. …
NAID 120005429604

Phosphatidylinositol 4-phosphate 5-kinase β regulates growth cone morphology and Semaphorin 3A-triggered growth cone collapse in mouse dorsal root ganglion neurons

Yamazaki Masakazu,Yamauchi Yohei,Goshima Yoshio,Kanaho Yasunori,金保安則
Neuroscience letters 547, 59-64, 2013-06
… Growth cone motility and morphology, which are critical for axon guidance, are controlled through intracellular events such as actin cytoskeletal reorganization and vesicular trafficking. …
NAID 120005316255

Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids

Obara Keisuke,Kojima Ryo,Kihara Akio
Journal of Lipid Research 54(3), 831-842, 2013-03
… Endosome-mediated vesicular trafficking pathways, including endocytosis and the CPY pathway, were severely impaired in sur4Δ vps21Δ double mutants, while the AP-3 pathway that bypasses the endosome was unaffected. … These results suggest that requirement of VLCFAs is especially high in the endosomal pathways, of all the intracellular trafficking pathways. …
NAID 120005228358