type 2 ryanodine receptor

• リアノジン受容体2型

関

cardiac ryanodine receptor、ryanodine receptor 2、RyR2

WordNet

1. write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
2. a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
3. (biology) the taxonomic group whose characteristics are used to define the next higher taxon
4. a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
5. all of the tokens of the same symbol; "the word `element contains five different types of character"
6. printed characters; "small type is hard to read"
7. identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
8. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
9. writing done with a typewriter (同)typewriting

PrepTutorEJDIC

1. 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
2. =sense organ / 受信装置

UpToDate Contents

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• 1. 溺死（水没事故） drowning submersion injuries
• 2. カテコラミン誘発多形性心室頻拍および他のQT間隔正常の多形性心室頻拍 catecholaminergic polymorphic ventricular tachycardia and other polymorphic ventricular tachycardias with a normal qt interval
• 3. 明らかな器質的心疾患のない患者における突然の心停止 sudden cardiac arrest in the absence of apparent structural heart disease
• 4. 不整脈原性右室心筋症の遺伝学および病因 genetics and pathogenesis of arrhythmogenic right ventricular cardiomyopathy
• 5. 拡張能障害の細胞学的機序 cellular mechanisms of diastolic dysfunction

English Journal

• Alterations in ryanodine receptors and related proteins in heart failure.

• Ather S, Respress JL, Li N, Wehrens XH.SourceDept of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA; Dept of Medicine (Cardiology), Baylor College of Medicine, Houston, TX, USA.
• Biochimica et biophysica acta.Biochim Biophys Acta.2013 Dec;1832(12):2425-31. doi: 10.1016/j.bbadis.2013.06.008. Epub 2013 Jun 14.
• Sarcoplasmic reticulum (SR) Ca(2+) release plays an essential role in mediating cardiac myocyte contraction. Depolarization of the plasma membrane results in influx of Ca(2+) through l-type Ca(2+) channels (LTCCs) that in turn triggers efflux of Ca(2+) from the SR through ryanodine receptor type-2 c
• PMID 23770282

• Mechanisms of Ca(2+) handling in zebrafish ventricular myocytes.

• Bovo E, Dvornikov AV, Mazurek SR, de Tombe PP, Zima AV.SourceDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, 2160 South First Avenue, Maywood, IL, 60153, USA.
• Pflügers Archiv : European journal of physiology.Pflugers Arch.2013 Dec;465(12):1775-84. doi: 10.1007/s00424-013-1312-2. Epub 2013 Jul 3.
• The zebrafish serves as a promising transgenic animal model that can be used to study cardiac Ca(2+) regulation. However, mechanisms of sarcoplasmic reticulum (SR) Ca(2+) handling in the zebrafish heart have not been systematically explored. We found that in zebrafish ventricular myocytes, the actio
• PMID 23821298

• Mutation E169K in Junctophilin-2 Causes Atrial Fibrillation Due to Impaired RyR2 Stabilization.

• Beavers DL, Wang W, Ather S, Voigt N, Garbino A, Dixit SS, Landstrom AP, Li N, Wang Q, Olivotto I, Dobrev D, Ackerman MJ, Wehrens XH.SourceCardiovascular Research Institute, Department of Molecular Physiology and Biophysics and Medicine (Cardiology), Baylor College of Medicine, Houston, Texas.
• Journal of the American College of Cardiology.J Am Coll Cardiol.2013 Nov 19;62(21):2010-9. doi: 10.1016/j.jacc.2013.06.052. Epub 2013 Aug 21.
• OBJECTIVES: This study sought to study the role of junctophilin-2 (JPH2) in atrial fibrillation (AF).BACKGROUND: JPH2 is believed to have an important role in sarcoplasmic reticulum (SR) Ca(2+) handling and modulation of ryanodine receptor Ca(2+) channels (RyR2). Whereas defective RyR2-mediated Ca(2
• PMID 23973696

Japanese Journal

• Construction and Expression of Ryanodine Receptor Mutants Relevant to Malignant Hyperthermia Patients in Japan

• NAKANO Masahide,OYAMADA Hideto,YAMAZAWA Toshiko,MURAYAMA Takashi,NANBA Hokuto,IIJIMA Kentaro,OGUCHI Katsuji
• The Showa University Journal of Medical Sciences 26(1), 27-38, 2014
• … Pharmacological and genetic analyses implicated the type 1 of ryanodine receptor (RyR1) /Ca2+ release channel as the main candidate gene for causing MH. … The caffeine sensitivity of Q156K-expressing cells was remarkably enhanced compared to wild-type RyR1 and similarly to previously reported levels for R164C-expressing cells, while that of the R534H mutants was not different from wild-type cells. …
• NAID 130004691842

• 2P201 悪性高熱症関連変異をもたらしている1型リアノジン受容体の機能解析(12.細胞生物的課題,ポスター,日本生物物理学会年会第51回(2013年度))

• Yamazawa Toshiko,Murayama Takashi,Oyamada Hideto,Suzuki Junji,Kanemaru Kazunori,Kurebayashi Nagomi,Iino Masamitsu,Takemori Shigeru
• 生物物理 53(SUPPLEMENT_1-2), S192, 2013-09-13
• NAID 110009819690

• 小西賞受賞者 ダントロレンによるリアノジン受容体を分子標的とした新しい心不全・不整脈治療

• 桝田 佳寛
• 山口医学 = Yamaguchi medical journal 62(1), 15-19, 2013-02
• … る.同様に,イヌ心不全モデルやCPVT型knock-inマウスにおいてもダントンは,RyR2に結合し,RyR2からのCa^{2+}漏出を抑制し,心不全の進展やCPVTを抑制する.このように,ダントロレンはRyR2を分子標的とした新しい心不全･不整脈治療薬となることが期待される.The inter-domain interaction between N-terminal(1-600)and central domains(2000-2500)of the ryanodine receptor(RyR)plays a critical role in channel gating in both skeletal(RyR1)and cardiac(RyR2)muscle …
• NAID 120005246291

Related Links

• Ryanodine receptor 2 - Wikipedia, the free encyclopedia

Ryanodine receptor 2 (RYR2) is a protein found primarily in cardiac muscle. In humans ... Calcium channel function is affected by the specific type of FK506 isomer interacting with the RYR2 protein, due to binding differences and other factors.

• Ryanodine receptor - Wikipedia, the free encyclopedia

Ryanodine receptors are similar to the inositol trisphosphate (IP3) receptor, and stimulated to transport Ca2+ into the cytosol ... It has also been shown that levels of type RyR3 are greatly increased in PC12 cells overexpressing mutant human ...

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★リンクテーブル★

リンク元	「リアノジン受容体2型」「RyR2」「cardiac ryanodine receptor」「ryanodine receptor 2」
関連記事	「type」「typed」「typing」

「リアノジン受容体2型」

　　[★]

英

type 2 ryanodine receptor、ryanodine receptor 2、cardiac ryanodine receptor、RyR2

関

リアノジン受容体、リアノジン受容体カルシウム放出チャネル、リアノジン受容体1型、心筋リアノジン受容体、リアノジン受容体3型

「RyR2」

　　[★]

• リアノジン受容体2型

関

cardiac ryanodine receptor、ryanodine receptor、ryanodine receptor 2、ryanodine receptor calcium release channel、RyR1、RyR3、type 2 ryanodine receptor

「cardiac ryanodine receptor」

　　[★]

• 心筋リアノジン受容体、リアノジン受容体2型

関

ryanodine receptor 2、RyR2、type 2 ryanodine receptor

「ryanodine receptor 2」

　　[★]

• リアノジン受容体2型

関

cardiac ryanodine receptor、RyR2、type 2 ryanodine receptor

「type」

　　[★]

• n.

• 型、タイプ、(生物)タイプ標本

(windows)ファイル内容表示(linux -> cat])

ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html

関

form、mode、pattern、type specimen、typed

　 　 　 　 　 　 　 　

「typed」

　　[★]

• adj.

• 型の

関

form、mode、pattern、type

「typing」

　　[★]

• n.

• タイプで打つこと、タイピング。分類