- 同
- TTKG
WordNet
- a graded change in the magnitude of some physical quantity or dimension
- the property possessed by a line or surface that departs from the horizontal; "a five-degree gradient" (同)slope
- a light soft silver-white metallic element of the alkali metal group; oxidizes rapidly in air and reacts violently with water; is abundant in nature in combined forms occurring in sea water and in carnallite and kainite and sylvite (同)K, atomic number 19
PrepTutorEJDIC
- (道路・鉄道などの)勾配(こうばい),傾斜度,グラジエント・斜面
- ポタシウム,カリウム(金属元素;化学記号はK)
UpToDate Contents
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English Journal
- Intrarenal urea recycling leads to a higher rate of renal excretion of potassium: an hypothesis with clinical implications.
- Kamel KS, Halperin ML.SourceaKeenan Research Centre in the Li Ka Shing Knowledge Institute, St. Michael's Hospital bDivision of Nephrology, University of Toronto, Toronto, Ontario, Canada.
- Current opinion in nephrology and hypertension.Curr Opin Nephrol Hypertens.2011 Sep;20(5):547-54.
- PURPOSE OF REVIEW: This review aims to illustrate why urea recycling may play an important role in potassium (K) excretion and to emphasize its potential clinical implications.RECENT FINDINGS: A quantitative analysis of the process of intrarenal urea recycling reveals that the amount of urea deliver
- PMID 21788894
- A case of hypokalemia-induced fatal arrhythmia caused by indapamide in an anorexic elderly patient.
- Ohashi N, Minemura S, Togawa A, Ohyama K.SourceDepartment of Nephrology, Numazu City Hospital, 550 Higashishiiji Azaharunoki, Numazu, 410-0302, Japan, nohashi@ma.tnc.ne.jp.
- Clinical and experimental nephrology.Clin Exp Nephrol.2011 Jun 15. [Epub ahead of print]
- An 84-year-old man was referred to our hospital for atrioventricular block and severe hypokalemia. He had been treated for hypertension since 2007 with indapamide, a thiazide-like diuretic. His laboratory data had not been tested for a long time. One week before his first visit, he suffered from a c
- PMID 21671161
Japanese Journal
- Thyrotoxic Periodic Paralysis Induced by Pulse Methylprednisolone
- Wongraoprasert Somporn,Buranasupkajorn Patinut,Sridama Vitaya,Snabboon Thiti
- Internal Medicine 46(17), 1431-1434, 2007
- … Hypokalemia from intracellular shift was confirmed by calculation of transtubular potassium gradient (TTKG). … His muscle strength and serum potassium fully recovered with a small amount of potassium replacement. …
- NAID 130000076066
- 正期産児および早期産児におけるTranstubular potassium concentration gradientの推移
- 川崎 幸彦,鈴木 順造,永井 真紀,片寄 雅彦,鈴木 仁
- 日本小児腎臓病学会雑誌 14(2), 129-133, 2001
- … Transtubular potassium concentration gradient (TTKG) は皮質集合管の主細胞に対するアルドステロン反応性の指標とされいる。 …
- NAID 130000077999
Related Links
- The trans-tubular potassium gradient (TTKG) is an index reflecting the conservation of potassium in the cortical collecting ducts (CCD) of the kidneys. It is useful in diagnosing the causes of hyperkalemia or hypokalemia. The TTKG estimates ...
★リンクテーブル★
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- 同
- transtubular potassium gradient, 細管カリウム勾配、尿細管カリウム勾配、経細管カリウム勾配、経尿細管カリウム勾配
[show details]
細管カリウム勾配 : 9 件
尿細管カリウム勾配 : 1 件
経細管カリウム勾配 : 0 件
経尿細管カリウム勾配 : 1 件
- 皮質集合管でのアルドステロン作用の指標
- 皮質集合管における尿細管腔のカリウム濃度の濃度勾配はアルドステロン作用によってもたらされるため、TTKGがアルドステロン作用が強ければ高くなる。
- Transtubular Potassium Gradient (TTKG) = (POsm * UPotassium ) / (PPotassium x UOsm)
判定
- 解釈はUosm＞Sosmの時のみ可能！ (濃縮尿であること)
- UCSF
- 参考2
- TTKG ＞10：有効循環血漿量の減少（脱水／HFなど） or K over intake
- TTKG ＜10：K 排泄障害が存在
- 参考1
- TTKG < 2 ：外的喪失
- TTKG > 2 ：腎性喪失
計算
参考
- http://intmed.exblog.jp/760245/
- http://generalsurgery.secret.jp/A_GUIDE_FOR_GENERAL_SURGEONS/fluid_%26_electrolytes/entori/2008/3/24_Hyperkalemia.html
- http://www.ne.jp/asahi/akira/imakura/hypokalemia.htm
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- 関
- ramp、slope