WordNet

prescribed by or according to regulation; "regulation army equipment"
(embryology) the ability of an early embryo to continue normal development after its structure has been somehow damaged or altered
the state of being controlled or governed
the act of bringing to uniformity; making regular (同)regularization, regularisation
the act of controlling or directing according to rule; "fiscal regulations are in the hands of politicians" (同)regulating
an authoritative rule (同)ordinance
(genetics) the process whereby genetic information coded in messenger RNA directs the formation of a specific protein at a ribosome in the cytoplasm
(mathematics) a transformation in which the origin of the coordinate system is moved to another position but the direction of each axis remains the same
the act of uniform movement (同)displacement
a written communication in a second language having the same meaning as the written communication in a first language (同)interlingual rendition, rendering, version
a uniform movement without rotation
rewording something in less technical terminology
of or relating to uniform movement without rotation

PrepTutorEJDIC

〈C〉『規則』,『規定』;法規,条例 / 〈U〉(…の)『規制』,『調整』《+『of』+『名』》 / 正規の,規定どおりの
〈U〉『訳すこと,翻訳』 / 〈C〉翻訳されたもの

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/18 13:41:13」(JST)

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[Wiki en表示]

Translational regulation refers to the control of the levels of protein synthesized from its mRNA. The corresponding mechanisms are primarily targeted on the control of ribosome recruitment on the initiation codon, but can also involve modulation of the elongation or termination of protein synthesis. In most cases, translational regulation involves specific RNA secondary structures on the mRNA.^[1]^[2]

References[edit source | edit]

^ Kozak M (1999). "Initiation of translation in prokaryotes and eukaryotes". Gene 234 (2): 187–208. doi:10.1016/S0378-1119(99)00210-3. PMID 10395892.
^ Malys N, McCarthy JEG (2010). "Translation initiation: variations in the mechanism can be anticipated". Cellular and Molecular Life Sciences 68 (6): 991–1003. doi:10.1007/s00018-010-0588-z. PMID 21076851. Unknown parameter |unused_data= ignored (help)

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UpToDate Contents

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1. 分子遺伝学の原理 principles of molecular genetics
2. 遺伝性疾患の基本原則 basic principles of genetic disease
3. 胃腸ペプチドの合成、分泌、および調節 synthesis secretion and regulation of gastrointestinal peptides
4. 鉄のバランス調節 regulation of iron balance
5. 甲状腺ホルモンの作用 thyroid hormone action

English Journal

New advances of DNA methylation in liver fibrosis, with special emphasis on the crosstalk between microRNAs and DNA methylation machinery.

Bian EB, Zhao B, Huang C, Wang H, Meng XM, Wu BM, Ma TT, Zhang L, Lv XW, Li J.SourceInstitute for Liver Diseases of Anhui Medical University (AMU), China; School of Pharmacy, Anhui Medical University, Hefei 230032, China.
Cellular signalling.Cell Signal.2013 Sep;25(9):1837-44. doi: 10.1016/j.cellsig.2013.05.017. Epub 2013 May 22.
Epigenetics refers to the study of heritable changes in the pattern of gene expression that is controlled by a mechanism specifically not due to changes the primary DNA sequence. Well-known epigenetic mechanisms include DNA methylation, post-translational histone modifications and RNA-based mechanis
PMID 23707524

Real-time in vivo monitoring of circadian E-box enhancer activity: A robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock.

Weger M, Weger BD, Diotel N, Rastegar S, Hirota T, Kay SA, Strähle U, Dickmeis T.SourceInstitute of Toxicology and Genetics, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, D-76344 Eggenstein-Leopoldshafen, Germany.
Developmental biology.Dev Biol.2013 Aug 15;380(2):259-73. doi: 10.1016/j.ydbio.2013.04.035. Epub 2013 May 9.
The circadian clock co-ordinates physiology and behavior with the day/night cycle. It consists of a transcriptional-translational feedback loop that generates self-sustained oscillations in transcriptional activity with a roughly 24h period via E-box enhancer elements. Numerous in vivo aspects of co
PMID 23665472

Gene therapy on demand: Site specific regulation of gene therapy.

Jazwa A, Florczyk U, Jozkowicz A, Dulak J.SourceDepartment of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Gene.Gene.2013 Aug 10;525(2):229-38. doi: 10.1016/j.gene.2013.03.093. Epub 2013 Apr 6.
Since 1990 when the first clinical gene therapy trial was conducted, much attention and considerable promise have been given to this form of treatment. Gene therapy has been used with success in patients suffering from severe combined immunodeficiency syndromes (X-SCID and ADA-deficiency), Leber's c
PMID 23566848

Japanese Journal

プロテオミクスで明らかになった核膜孔複合体の翻訳後修飾による機能制御 (特集核-細胞質間分子輸送システム : 基本分子メカニズムの理解とその応用)

小迫英尊
生化学 87(1), 49-55, 2015-02
NAID 40020383555

Sulforaphane down-regulates SKP2 to stabilize p27^<KIP1> for inducing antiproliferation in human colon adenocarcinoma cells(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)

Chung Yuan-Kai,Or Richard Chi-Hung,Lu Chien-Hsing,Ouyang Wei-Ting,Yang Shu-Yi,Change Chia-Che
Journal of bioscience and bioengineering 119(1), 35-42, 2015-01
… Of note, sulforaphane-induced anti-proliferation was accompanied with down-regulation of SKP2, leading to the stabilization and thus up-regulation of p27^<KIP1>. … depletion, therefore highlighting the important role of SKP2 down-regulation and the ensuing stabilization of p27^<KIP1> …
NAID 110009892230

MicroRNA profling in ethylene glycol monomethyl ether-induced monkey testicular toxicity model

, , , , , ,
The Journal of Toxicological Sciences 40(3), 375-382, 2015
… Furthermore, down-regulation of miR-34b-5p and miR-449a, which are enriched in meiotic cells like pachytene spermatocytes, was obvious in the testis, suggesting that these spermatogenic cells were damaged by the EGME treatment. …
NAID 130005068424