tick-borne encephalitis virus

• ダニ媒介性脳炎ウイルス

関

Langat virus、louping ill virus、Powassan virus

WordNet

1. make a sound like a clock or a timer; "the clocks were ticking"; "the grandfather clock beat midnight" (同)ticktock, ticktack, beat
2. a light mattress
3. any of two families of small parasitic arachnids with barbed proboscis; feed on blood of warm-blooded animals
4. a metallic tapping sound; "he counted the ticks of the clock" (同)ticking
5. sew; "tick a mattress" (同)retick
6. a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
7. (virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
8. a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
9. shrub with terminal tufts of elongated leaves used locally for thatching and clothing; thick sweet roots are used as food; tropical southeastern Asia, Australia and Hawaii (同)Cordyline terminalis
10. the syllable naming the seventh (subtonic) note of any musical scale in solmization (同)te, si
11. brought into existence; "he was a child born of adultery"

PrepTutorEJDIC

1. (時計まどの)カチカチ[という音] / 《英語》瞬間 / 照合(点検)済みの印,チェック / 〈時計などが〉カチカチ音がする《+away》 / 〈時が〉過ぎる,経過する∥+by(away)》 / 《話》〈人が〉行動する,〈機械などが〉動く
2. 〈C〉(ふとん・まくらなどの)表布
3. ダニ
4. ビールス,ろ過性病原体
5. シ(全音階の第7音)
6. bear〈他〉1の過去分詞(受動態にのみ用いる) / 《名詞の前にのみ用いて》『生まれながらの』,先天的な(innate) / 『生まれた』;生じた
7. bearの過去分詞

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/13 11:43:18」(JST)

wiki en

[Wiki en表示]

Tick-borne meningoencephalitis virus
Virus classification
Group:	Group IV ((+)ssRNA)
Family:	Flaviviridae
Genus:	Flavivirus
Species:	Tick-borne meningoencephalitis virus

Tick-borne encephalitis virus (TBEV) is the virus associated with tick-borne encephalitis.

Taxonomy

TBEV is a member of the genus Flavivirus. Other close relatives include Omsk hemorrhagic fever virus, Kyasanur forest disease virus, Alkhurma virus, Louping ill virus and the Langat virus.

Subtypes

TBEV has three subtypes:

• Western European subtype (formerly Central European encephalitis virus, CEEV; principal tick vector: Ixodes ricinus);
• Siberian subtype (formerly West Siberian virus; principal tick vector: Ixodes persulcatus);
• Far Eastern subtype (formerly Russian Spring Summer encephalitis virus, RSSEV; principal tick vector: Ixodes persulcatus).

The reference strain is the Sofjin strain.

Evolution

The ancestor of the extant strains appears to have separated into several clades approximately 2750 years ago. The Siberian and Far Eastern subtypes diverged about 2250 years ago.

A second analysis suggests an earlier date of evolution (3300 years ago) with a rapid increase in the number of strains starting ~300 years ago.

This virus has been transmitted at least three times into Japan between 260–430 years ago.

The strains circulating in Latvia appear to have originated from both Russia and Western Europe while those in Estonia appear to have originated in Russia. The Lithuanian strains appear to be related to those from Western Europe.

References

External links

• Encephalitis Viruses, Tick-Borne at the US National Library of Medicine Medical Subject Headings (MeSH)

UpToDate Contents

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• 1. 節足動物媒介性脳炎 arthropod borne encephalitides
• 2. ウイルス性髄膜炎：小児におけるマネージメント、予後、および予防 viral meningitis management prognosis and prevention in children
• 3. ライム病の治療 treatment of lyme disease
• 4. 旅行者のための予防接種 immunizations for travel
• 5. ライム病疑いのあるダニ咬傷の評価 evaluation of a tick bite for possible lyme disease

English Journal

• Specificities of Human CD4+ T Cell Responses to an Inactivated Flavivirus Vaccine and Infection: Correlation with Structure and Epitope Prediction.

• Schwaiger J1, Aberle JH1, Stiasny K1, Knapp B2, Schreiner W3, Fae I4, Fischer G4, Scheinost O5, Chmelik V6, Heinz FX7.
• Journal of virology.J Virol.2014 Jul 15;88(14):7828-42. doi: 10.1128/JVI.00196-14. Epub 2014 Apr 30.
• Tick-borne encephalitis (TBE) virus is endemic in large parts of Europe and Central and Eastern Asia and causes more than 10,000 annual cases of neurological disease in humans. It is closely related to the mosquito-borne yellow fever, dengue, Japanese encephalitis, and West Nile viruses, and vaccina
• PMID 24789782

• Identification of linear human B-cell epitopes of tick-borne encephalitis virus.

• Kuivanen S1, Hepojoki J, Vene S, Vaheri A, Vapalahti O.
• Virology journal.Virol J.2014 Jun 19;11(1):115. doi: 10.1186/1743-422X-11-115.
• BACKGROUND: Tick-borne encephalitis (TBE) is a central nervous system infection transmitted to humans by ticks. The causative agent, tick-borne encephalitis virus (TBEV), belongs to the genus Flavivirus (family Flaviviridae), which includes globally important arthropod-borne viruses, such as dengue,
• PMID 24946852

• Protective role of TNF-α, IL-10 and IL-2 in mice infected with the Oshima strain of Tick-borne encephalitis virus.

• Tun MM1, Aoki K1, Senba M2, Buerano CC1, Shirai K3, Suzuki R3, Morita K1, Hayasaka D1.
• Scientific reports.Sci Rep.2014 Jun 18;4:5344. doi: 10.1038/srep05344.
• Tick-borne encephalitis virus (TBEV) causes acute central nervous system disease. Here, we investigated the roles of the TNF-α, IL-10 and other cytokines in appropriate KO mice following infection with Oshima and Sofjin strains of TBEV. Following infection with the Oshima strain, mortality rates we
• PMID 24938868

Japanese Journal

• Protective role of TNF-α, IL-10 and IL-2 in mice infected with the Oshima strain of Tick-borne encephalitis virus

• Tun Mya Myat Ngwe,Aoki Kotaro,Senba Masachika,Buerano Corazon C.,Shirai Kenji,Suzuki Ryuji,Morita Kouichi,Hayasaka Daisuke
• Scientific Reports 4, 5344, 2014-06-18
• … Tick-borne encephalitis virus (TBEV) causes acute central nervous system disease. … From these results, we suggest that TNF-α, IL-10 and IL-2 are key factors for disease remission from fatal encephalitis due to infection with Oshima strain of TBEV. …
• NAID 120005457095

• A Critical Determinant of Neurological Disease Associated with Highly Pathogenic Tick-Borne Flavivirus in Mice

• Yoshii Kentaro,Sunden Yuji,Yokozawa Kana,Igarashi Manabu,Kariwa Hiroaki,Holbrook Michael R.,Takashima Ikuo
• Journal of Virology 88(10), 5406-5420, 2014-05
• … Tick-borne encephalitis virus (TBEV) and Omsk hemorrhagic fever virus (OHFV) are highly pathogenic tick-borne flaviviruses; … In this study, chimeric viruses incorporating components of TBEV and OHFV were generated using infectious clone technology, and their pathological characteristics were analyzed in a mouse model to identify virus-specific determinants of disease. …
• NAID 120005496501

• The variable region of the 3' untranslated region is a critical virulence factor in the Far-Eastern subtype of tick-borne encephalitis virus in mouse model

• Sakai Mizuki,Yoshii Kentaro,Sunden Yuji,Yokozawa Kana,Hirano Minato,Kariwa Hiroaki
• Journal of General Virology 95(4), 823-835, 2014-04
• … Tick-borne encephalitis virus (TBEV) is a major arbovirus that causes thousands of cases of severe neurological illness in humans annually. … At the terminal phase of viral infection in mice, the virus titre of the Oshinna-based chimeric virus with the variable region of the 3' UTR of Sofjin reached a level identical to that of Sofjin and showed a similar histopathological change in the brain tissue. …
• NAID 120005575003

Related Links

• Tick-borne Encephalitis (TBE) | CDC

Tick-borne encephalitis, or TBE, is a human viral infectious disease involving the central nervous system. TBE is caused by the tick-borne encephalitis virus (TBEV), a member of the family Flaviviridae, and was initially ...

• Tick Borne Encephalitis

Tick-borne encephalitis (TBE) is caused by an RNA virus known, simply, as “tick-borne encephalitis virus,” or TBEV. The virus belongs to the genus Flavivirus, which contains several dozen human pathogens, including the causative ...

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★リンクテーブル★

リンク元	「Langat virus」「ダニ媒介性脳炎ウイルス」「ダニ媒介脳炎ウイルス」
拡張検索	「Far eastern tick-borne encephalitis virus」
関連記事	「borne」「tick」「virus」

「Langat virus」

　　[★]

ランガットウイルス、Langatウイルス

関

louping ill virus、Powassan virus、tick-borne encephalitis virus

「ダニ媒介性脳炎ウイルス」

　　[★]

英

tick-borne encephalitis virus

関

ランガットウイルス、跳躍病ウイルス、・ワッサンウイルス

「ダニ媒介脳炎ウイルス」

　　[★]

英

tick-borne encephalitis virus

関

ダニ媒介脳炎

「Far eastern tick-borne encephalitis virus」

　　[★] 極東ダニ脳炎ウイルス

「borne」

　　[★]

• vt. bearのpp.

関

come from, derive, descend, stem

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-borne

• ～によって運ばれる、伝えられる
• ex.

• water-borne：水媒介性の
• blood-borne：血液由来の
• air-borne infection,airborne infection ：空気感染

　

「tick」

　　[★] ダニ 　 　 　 　 　 　 　 　

「virus」

　　[★] ウイルス