関: louping ill virus、Powassan virus、tick-borne encephalitis virus

WordNet

a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
(virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus

PrepTutorEJDIC

ビールス,ろ過性病原体

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/30 05:23:11」(JST)

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Langat virus (LGTV) is a virus of the genus Flavivirus. For the first time Langat virus was isolated in Malaysia and Thailand. This virus is close to Omsk hemorrhagic fever virus, Kyasanur forest disease virus, Alkhurma virus, Louping ill virus and the Tick-borne encephalitis virus. The Langat virus does not pose significant epidemiological threat in comparison with TBEV. There are no known cases of human diseases associated with LGTV, however antibodies to this virus have been detected in the sera of local people.^[1]

LGTV-based vaccine

In the 1970s a live attenuate LGTV-based vaccine against tick-borne encephalitis was made. At the same time, another vaccine was tested, but the group vaccinated with the LGTV-based vaccine had the lowest level of developing infection decease.^[2] However, there were two big problems: the high level incidents of encephalitis (1:10 000) and not absolute protection from infection in endemic regions.

References

^ Gritsun TS, Lashkevich VA, Gould EA (January 2003). "Tick-borne encephalitis". Antiviral Res 57 (1–2): 129–46. doi:10.1016/S0166-3542(02)00206-1. PMID 12615309.
^ Shapoval AN, Kamalov II, Denisova EIu, Sokolova ED, Luzin PM, Shamarina AG, Gusmanova AG, Pinaeva NI (1989). "Study of the distant consequences of immunizing people with a live vaccine against tick-borne encephalitis". Tr Inst Im Pastera (in Russian) 65: 133–5. PMID 2629181.

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English Journal

Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013.

Watson SJ1, Langat P1, Reid SM2, Lam TT3, Cotten M1, Kelly M2, Van Reeth K4, Qiu Y4, Simon G5, Bonin E5, Foni E6, Chiapponi C6, Larsen L7, Hjulsager C7, Markowska-Daniel I8, Urbaniak K8, Dürrwald R9, Schlegel M9, Huovilainen A10, Davidson I11, Dán Á12, Loeffen W13, Edwards S1, Bublot M14, Vila T14, Maldonado J15, Valls L15; ESNIP3 Consortium, Brown IH2, Pybus OG3, Kellam P16.
Journal of virology.J Virol.2015 Oct 1;89(19):9920-31. doi: 10.1128/JVI.00840-15. Epub 2015 Jul 22.
The emergence in humans of the A(H1N1)pdm09 influenza virus, a complex reassortant virus of swine origin, highlighted the importance of worldwide influenza virus surveillance in swine. To date, large-scale surveillance studies have been reported for southern China and North America, but such data ha
PMID 26202246

Detection of Langat virus by TaqMan real-time one-step qRT-PCR method.

Muhd Radzi SF1, Rückert C2, Sam SS1, Teoh BT1, Jee PF1, Phoon WH1, Abubakar S1, Zandi K1.
Scientific reports.Sci Rep.2015 Sep 11;5:14007. doi: 10.1038/srep14007.
Langat virus (LGTV), one of the members of the tick-borne encephalitis virus (TBEV) complex, was firstly isolated from Ixodes granulatus ticks in Malaysia. However, the prevalence of LGTV in ticks in the region remains unknown. Surveillance for LGTV is therefore important and thus a tool for specifi
PMID 26360297

Functional non-coding RNAs derived from the flavivirus 3' untranslated region.

Clarke BD1, Roby JA1, Slonchak A1, Khromykh AA2.
Virus research.Virus Res.2015 Aug 3;206:53-61. doi: 10.1016/j.virusres.2015.01.026. Epub 2015 Feb 7.
Flaviviruses are single-stranded positive sense RNA enveloped viruses. The flavivirus genus includes important human pathogens such as dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and Murray Valley ence
PMID 25660582

Japanese Journal

Detection of Flaviviruses by Reverse Transcriptase-Polymerase Chain Reaction with the Universal Primer Set

, , , , , , ,
MICROBIOLOGY and IMMUNOLOGY 41(3), 209-213, 1997
… Using a universal primer set designed to match the sequence of the NS1 gene of flaviviruses, the virus RNA of dengue (DEN), Japanese encephalitis (JEV), powassan and langat of Flaviviridae were successfully amplified by polymerase chain reaction (PCR) via cDNA; …
NAID 130003484490

Antigenic Analysis of Flaviviruses with Monoclonal Antibodies against Negishi Virus

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MICROBIOLOGY and IMMUNOLOGY 28(9), 1023-1030, 1984
… Twelve monoclonal antibodies against Negishi virus were obtained and characterized by hemagglutination inhibition (HI) and neutralization (NT) tests using five flaviviruses isolated in the pan-Pacific region. … The reaction pattern of the antibodies showed that Negishi virus was most closely related to Langat virus, followed by 3-Arch, JE and Apoi viruses in that order. …
NAID 130003405663