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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/02/19 17:23:58」(JST)

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English Journal

  • Pharmacokinetics, pharmacodynamics and toxicity of a combination of metoprolol succinate and telmisartan in Wistar albino rats: Safety profiling.
  • Nandi U, Karmakar S, Das AK, Ghosh B, Padman A, Chatterjee N, Pal TK.SourceDepartment of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India.
  • Regulatory toxicology and pharmacology : RTP.Regul Toxicol Pharmacol.2013 Feb;65(1):68-78. doi: 10.1016/j.yrtph.2012.11.001. Epub 2012 Nov 27.
  • Metoprolol succinate (MET), a cardioselective β blocker and telmisartan (TEL), an angiotensin receptor blocker were administered orally, both individually and in combination to Wistar albino rats for evaluation of their pharmacokinetics, pharmacodynamics and repeated dose oral toxicity (28days). Ph
  • PMID 23201407
  • Effects of telmisartan and valsartan on insulin sensitivity in obese diabetic mice.
  • Ushijima K, Takuma M, Ando H, Ishikawa-Kobayashi E, Nozawa M, Maekawa T, Shiga T, Fujimura A.SourceDivision of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
  • European journal of pharmacology.Eur J Pharmacol.2013 Jan 5;698(1-3):505-10. doi: 10.1016/j.ejphar.2012.11.022. Epub 2012 Nov 27.
  • Telmisartan and valsartan have angiotensin II receptor blocking activity. Because telmisartan has also an agonistic action for peroxisome proliferators-activator receptor (PPAR)-γ, it is speculated that an effect of telmisartan on insulin sensitivity is different from that of valsartan, which lacks
  • PMID 23195328

Japanese Journal

  • Ameliorative Effects of Telmisartan on the Inflammatory Response and Impaired Spatial Memory in a Rat Model of Alzheimer’s Disease Incorporating Additional Cerebrovascular Disease Factors
  • Shindo Taro,Takasaki Kotaro,Uchida Kanako [他]
  • Biological & pharmaceutical bulletin 35(12), 2141-2147, 2012-12
  • NAID 40019497527
  • Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2^<Akita> diabetic mice
  • Hypertension research : clinical and experimental : official journal of the Japanese Society of Hypertension 35(2), 213-220, 2012-02-01
  • NAID 10030643820
  • 陽電子画像診断を用いた経口投与された医薬品の体内動態解析
  • 片岡 誠
  • 薬学雑誌 132(8), 911-917, 2012
  • … After oral administration of 11C-labeled telmisartan with or without non-radiolabeled telmisartan, systemic bioavailability and hepatic distribution of radioactivity significantly increased non-linearly with dose. … In the intestinal lumen, telmisartan and its glucuronide, converted by UDP-glucuronosyl transferase (UGT), were detected and the ratio of telmisartan decreased at a high dose of telmisartan. …
  • NAID 130001888709

Related Links

Telmisartan (Micardis) is an ARB prescribed for the treatment of high blood pressure and the prevention of heart attack, stroke, and cardiovascular events in patients at risk. ... GENERIC NAME: telmisartan BRAND NAME: Micardis ...
Telmisartan is also used sometimes to treat congestive heart failure (condition in which the heart is unable to pump enough blood to the rest of the body) and diabetic nephropathy (kidney disease in people with diabetes ...

Related Pictures

TelmisartanTelmisartán KERN PHARMA EFG PrintTelmisartan synthesis: [ 16 ]Telmisartán Medi Mart tabletas 14 piezas Micardis Telmisartan 80 Mg Boxtelmisartan tablets we offer telmisartan




  • テルミサルタンはロサルタンなどを始めとするARBと構造的に異なる。tetrazole構造がなく、脂溶性が高い。ARBでは心血管保護作用がないが、テルミサルタンはCD36、PPARγ、PPARαの発現を増やすことなどの機序により血管保護作用を有する。
  • 用量:40mg1日1回, 1日最大用量は80mgまで。
  • 剤形:40mg錠