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WordNet

wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
a fully differentiated structural and functional unit in an animal that is specialized for some particular function
a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
a periodical that is published by a special interest group; "the organ of the communist party"
intend (something) to move towards a certain goal; "He aimed his fists towards his opponents face"; "criticism directed at her superior"; "direct your anger towards others, not towards yourself" (同)aim, place, direct, point
sports equipment consisting of an object set up for a marksman or archer to aim at (同)butt
a reference point to shoot at; "his arrow hit the mark" (同)mark
the location of the target that is to be hit (同)target area

PrepTutorEJDIC

『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
(鉄砲などの)『標的』,的,攻撃目標 / (批評・軽べつなどの)的,種《+of+名》 / (行為などの)目標,到達目標

UpToDate Contents

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1. 臓器提供の候補となる小児患者（ポテンシャルドナー）の評価 assessment of the pediatric patient for potential organ donation
2. 実質臓器移植受容者における皮膚癌のマネージメント management of skin cancer in solid organ transplant recipients
3. 敗血症の病態生理 pathophysiology of sepsis
4. 腎臓移植における臓器共有（organ sharing） organ sharing in kidney transplantation
5. 女性における骨盤臓器脱：疫学、危険因子、臨床症状、およびマネージメントの概要 pelvic organ prolapse in women an overview of the epidemiology risk factors clinical manifestations and management

English Journal

[Nanopathology as a new scientific disciplineMinireview].

Dvořáčková J, Bielniková H, Mačák J.AbstractThe detection of metal particles in the pathologically altered tissues (eg. in inflammatory lesions or tumors) led to the idea that they might be associated with emergence of some idiopathic diseases. To understand the etiopathogenesis of diseases associated with the presence of nanoparticles in the tissue there is a new area of patology - nanopathology. Numerous studies have shown that nanoparticles can enter the human body through inhalation or ingestion. Through the pulmonary alveoli, skin and intestinal mucosa, the nanoparticles may reach the blood and lymphatic system, which subsequently distributes them to other target organs. Epithelial surfaces of conjunctiva and skin represent another potential way of penetration of nanoparticles into the body. There is a number of studies, which described the adverse effects of ultrafine particles on respiratory and cardiovascular system. Recent studies have also shown that some nanoparticles are able to pass through the pores of the nuclear membrane, where they may pose a risk of damage to cells and genetic information and they are also potentially capable to cross the placental and hematoencephalic barriers. Further, their role in the induction of oxidative stress is significant in relation to the mutagenesis. Scanning electron microscopy with energy disperse spectroscopy (SEM-EDS) represents a suitable tool for identification of metal-based particles in tissues and body fluids. Importance of nanopathogy can be seen in the elucidation of the etiopathogenesis of many diseases, not only of respiratory and cardiovascular systems, but also of many other organ systems. Keywords: nanoparticles - nanopathology - diseases of nanoparticles (nanopathologies) - ESEM-EDS.
Ceskoslovenská patologie.Cesk Patol.2013 Dec;49(1):46-50.
The detection of metal particles in the pathologically altered tissues (eg. in inflammatory lesions or tumors) led to the idea that they might be associated with emergence of some idiopathic diseases. To understand the etiopathogenesis of diseases associated with the presence of nanoparticles in the
PMID 23432076

A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity.

Mohan JF, Unanue ER.SourceDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Molecular immunology.Mol Immunol.2013 Sep;55(2):166-8. doi: 10.1016/j.molimm.2012.10.024. Epub 2012 Nov 27.
We describe here a pathway of presentation involving peptides or denatured proteins that generate unique peptide-MHC complexes. Such complexes select for non-conventional CD4 T cells. We have examined this pathway and the corresponding CD4 T cells in diabetic autoimmunity. Autoimmunity requires both
PMID 23200226

Preparative isolation and purification of seven main antioxidants from Eucommia ulmoides Oliv. (Du-zhong) leaves using HSCCC guided by DPPH-HPLC experiment.

Dai X, Huang Q, Zhou B, Gong Z, Liu Z, Shi S.SourceDepartment of Integrated Traditional Chinese and Western Medicine, Key Laboratory of Traditional Chinese Medicine Gan Organ of SATCM, Central South University, Xiangya Hospital, Changsha 410008, PR China.
Food chemistry.Food Chem.2013 Aug 15;139(1-4):563-70. doi: 10.1016/j.foodchem.2013.02.006. Epub 2013 Feb 16.
Seven antioxidants were purified from Eucommia ulmoides Oliv. leaves using HSCCC guided by DPPH-HPLC experiment. HSCCC was successfully used to separate target antioxidants by three runs with different solvent systems after D101 column chromatography fractionation. Ethyl acetate-n-butanol-water (1:2
PMID 23561146

Japanese Journal

A crossover comparison of urinary albumin excretion as a new surrogate marker for cardiovascular disease among 4 types of calcium channel blockers

Konoshita Tadashi,Makino Yasukazu,Kimura Tomoko,Fujii Miki,Morikawa Norihiro,Wakahara Shigeyuki,Arakawa Kenichiro,Inoki Isao,Nakamura Hiroyuki,Miyamori Isamu
International Journal of Cardiology 166(2), 448-452, 2013-06-20
… Background: At the intervention for cardiovascular disease (CVD), albuminuria is a new pivotal target. … Thus, it is suggested that the 2 CCBs might be favorable for organ protection in hypertensives. …
NAID 120005302291

Growth factor-dependent and independent regulation of skeletal muscle mass - Is IGF-1 necessary for skeletal muscle hypertrophy? -

Miyazaki Mitsunori
The Journal of Physical Fitness and Sports Medicine 2(1), 101-106, 2013
… Pituitary growth hormone (GH) and insulin-like growth factor-1 (IGF-1) play a critical role in the regulation of postnatal organ growth and overall body size. …
NAID 130003379931

放射線治療計画装置を用いたkV-CBCT吸収線量評価～前立腺がん放射線治療に及ぼす影響～

川村哲朗,村上直基,岡村佳明,西村英輝,宮脇大輔,木村邦彦,土師守,佐々木良平
日本放射線技術学会雑誌 69(5), 491-499, 2013
… In radiation therapy for prostate cancer, if kV-CBCT was applied daily, the dose increment within the planning target volume (PTV) and the organ in question was about 1 Gy. …
NAID 130003367674

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