WordNet
- intend (something) to move towards a certain goal; "He aimed his fists towards his opponents face"; "criticism directed at her superior"; "direct your anger towards others, not towards yourself" (同)aim, place, direct, point
- sports equipment consisting of an object set up for a marksman or archer to aim at (同)butt
- a reference point to shoot at; "his arrow hit the mark" (同)mark
- the location of the target that is to be hit (同)target area
- (physics and chemistry) the simplest structural unit of an element or compound
PrepTutorEJDIC
- (鉄砲などの)『標的』,的,攻撃目標 / (批評・軽べつなどの)的,種《+of+名》 / (行為などの)目標,到達目標
- 分子《略》『mol』) / (一般に)(…の)微量《+『of』+『名』》
UpToDate Contents
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English Journal
- MiR-27a ameliorates inflammatory damage to the blood-spinal cord barrier after spinal cord ischemia: reperfusion injury in rats by downregulating TICAM-2 of the TLR4 signaling pathway.
- Li XQ1, Lv HW, Wang ZL, Tan WF, Fang B, Ma H.
- Journal of neuroinflammation.J Neuroinflammation.2015 Dec;12(1):246. doi: 10.1186/s12974-015-0246-3. Epub 2015 Feb 7.
- BACKGROUND: Spinal cord ischemia reperfusion (IR) injury causes inflammation and subsequently increases blood-spinal cord barrier leakage and Toll-like receptor 4 (TLR4) pathway activation. MicroRNAs (miRs) effectively regulate numerous target mRNAs during ischemia. However, their roles during IR in
- PMID 25779433
- Small organic molecule disruptors of Cav3.2 - USP5 interactions reverse inflammatory and neuropathic pain.
- Gadotti VM1, Caballero AG, Berger ND, Gladding CM, Chen L, Pfeifer TA, Zamponi GW.
- Molecular pain.Mol Pain.2015 Dec;11(1):11. doi: 10.1186/s12990-015-0011-8. Epub 2015 Mar 14.
- BACKGROUND: Cav3.2 channels facilitate nociceptive transmission and are upregulated in DRG neurons in response to nerve injury or peripheral inflammation. We reported that this enhancement of Cav3.2 currents in afferent neurons is mediated by deubiquitination of the channels by the deubiquitinase US
- PMID 25775966
- Colorimetric detection of microcystin-LR based on disassembly of orient-aggregated gold nanoparticle dimers.
- Wang F1, Liu S1, Lin M1, Chen X1, Lin S1, Du X1, Li H1, Ye H1, Qiu B1, Lin Z1, Guo L2, Chen G1.
- Biosensors & bioelectronics.Biosens Bioelectron.2015 Jun 15;68:475-80. doi: 10.1016/j.bios.2015.01.037. Epub 2015 Jan 17.
- Recently we demonstrated oriented formation of gold nanoparticle (AuNP) dimers for ultrasensitive sensing oligonucleotides (J. Am. Chem. Soc. 2013, 135, 12338). Herein, we investigate the reverse process of this sensing mechanism using target analytes to disassemble the orient-aggregated AuNP dimers
- PMID 25621999
Japanese Journal
- Inhibition of T cell activation through down-regulation of TCR-CD3 expression mediated by an anti-CD90 Ab.
- Nishida Emi,Chen Chen,Morita Akimichi,Shimizu Jun
- Immunology letters 136(2), 163-170, 2011-05
- … Biochemical experiments demonstrated that LP5 recognized the Thy-1 (CD90) molecule. … Based on these observations, we propose that CD3 down-regulation without any stimulatory activity against T cells could be one approach to inhibiting T cell activation, and CD90 would be an appropriate target. …
- NAID 120003001401
- A synthetic compound that potentiates bone morphogenetic protein-2-induced transdifferentiation of myoblasts into the osteoblastic phenotype
- Kato Satoshi,Sangadala Sreedhara,Tomita Katsuro,Titus Louisa,Boden Scott D.
- Molecular and Cellular Biochemistry 349(1-2), 97-106, 2011-03
- … Here, we report a specific compound, SVAK-12, which was selected based on in silico screenings of small-molecule databases using the homology modeled interaction motif of Smurf1-WW2 domain. … Smurf1 is an interesting potential target to enhance bone formation based on the positive effects on bone of proteins that block Smurf1-binding to Smad targets or in Smurf1-/- knockout mice. …
- NAID 120002907449
Related Links
- target moleculeの意味や和訳。 標的分子 - 約486万語ある英和辞典・和英辞典。発音・ イディオムも分かる英語辞書。
Related Pictures
★リンクテーブル★
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- 英
- target molecule
- 関
- ターゲット分子
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- 英
- target molecule
- 関
- 標的分子
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- 関
- mol、molecular、numerator
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ターゲティング、標的指向化