suicide gene therapy

WordNet

1. (medicine) the act of caring for someone (as by medication or remedial training etc.); "the quarterback is undergoing treatment for a knee injury"; "he tried every treatment the doctors suggested"; "heat therapy gave the best relief"
2. the act of killing yourself; "it is a crime to commit suicide" (同)self-destruction, self-annihilation
3. a person who kills himself intentionally (同)felo-de-se
4. (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
5. informal term for information; "give me the gen on your new line of computers"

PrepTutorEJDIC

1. (病気の)治療,療法 / =psychotherapy
2. 〈U〉自殺 / 〈C〉『自殺的行為,』自滅 / 〈C〉自殺者;自殺行為
3. 遺伝子

UpToDate Contents

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• 1. パーキンソン病の外科治療 surgical treatment of parkinson disease
• 2. アデノウイルスの病因およびベクター使用 adenovirus pathogenesis and vector applications
• 3. 成人における自殺念慮および自殺行動 suicidal ideation and behavior in adults
• 4. 原発性免疫不全症に対する遺伝子治療 gene therapy for primary immunodeficiency
• 5. 安楽死および医師幇助自殺 euthanasia and physician assisted suicide

English Journal

• Low-dose cisplatin converts the tumor microenvironment into a permissive state for HSVtk-induced antitumor immunity in HPV16-related tonsillar carcinoma.

• Goh AR1, Shin SP1, Jung NR1, Ryu CH2, Eom HS3, Lee JH4, Choi K5, Lee SJ6, Jung YS7.
• Cancer letters.Cancer Lett.2015 Jan 28;356(2 Pt B):743-50. doi: 10.1016/j.canlet.2014.10.022. Epub 2014 Oct 24.
• An adenovirus harboring the HSV thymidine kinase (HSVtk) gene under the regulation of a trans-splicing ribozyme that targets telomerase is cytotoxic to cancer cells because it inhibits DNA replication (Ad5mTR). Furthermore, it induces anti-tumor immunity by activating cytotoxic T cells. Because mult
• PMID 25449436

• Poly(aspartic acid)-based Degradable Assemblies for Highly Efficient Gene Delivery.

• Nie JJ1, Dou XB, Hu H, Yu B, Chen DF, Wang RX, Xu FJ.
• ACS applied materials & interfaces.ACS Appl Mater Interfaces.2015 Jan 14;7(1):553-62. doi: 10.1021/am506730t. Epub 2014 Dec 24.
• Due to its good properties such as low cytotoxicity, degradability, and biocompatibility, poly(aspartic acid) (PAsp) is a good candidate for the development of new drug delivery systems. In this work, a series of new PAsp-based degradable supramolecular assemblies were prepared for effective gene th
• PMID 25434705

• Genetically engineered theranostic mesenchymal stem cells for the evaluation of the anticancer efficacy of enzyme/prodrug systems.

• Nouri FS1, Wang X1, Hatefi A2.
• Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2015 Jan 7;200C:179-187. doi: 10.1016/j.jconrel.2015.01.003. [Epub ahead of print]
• Over the past decade, various enzyme/prodrug systems such as thymidine kinase/ganciclovir (TK/GCV), yeast cytosine deaminase/5-fluorocytosine (yCD/5-FC) and nitroreductase/CB1954 (NTR/CB1954) have been used for stem cell mediated suicide gene therapy of cancer. Yet, no study has been conducted to co
• PMID 25575867

Japanese Journal

• 放射線応答性遺伝子発現制御システムの開発

• 小川 良平,森井 章裕,渡部 明彦 [他]
• 放射線生物研究 48(3), 267-279, 2013-09
• NAID 40019814127

• Therapeutic effect of suicide gene-transferred mesenchymal stem cells in a rat model of glioma

• Kosaka H,Ichikawa T,Kurozumi K,Kambara H,Inoue S,Maruo T,Nakamura K,Hamada H,Date I
• Cancer Gene
• … We evaluated a new therapeutic strategy for malignant glioma, which combines intratumoral inoculation of mesenchymal stem cells (MSCs) expressing cytosine deaminase gene with 5-fluorocytosine (5-FC) administration. … For in vitro and in vivo experiments, MSCs were transfected with adenovirus carrying either enhanced green fluorescent protein gene (AdexCAEGFP) or cytosine deaminase gene (AdexCACD), to establish MSC-expressing EGFP (MSC-EGFP) or CD (MSC-CD). …
• NAID 120005232495

• Membrane-bound form of monocyte chemoattractant protein-1 enhances antitumor effects of suicide gene therapy in a model of hepatocellular carcinoma

• Marukawa Yohei,Nakamoto Yasunari,Kakinoki Kaheita,Tsuchiyama Tomoya,Iida Noriho,Kagaya Takashi,Sakai Yoshio,Naito Makoto,Mukaida Naofumi,Kaneko Shuichi
• Cancer Gene
• … Suicide gene therapy using the herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV) system combined with monocyte chemoattractant protein-1 (MCP-1) provides significant antitumor efficacy. … A recombinant adenovirus vector (rAd) harboring the human MCP-1 gene and the membrane-spanning domain of the CX3CL1 gene was used. …
• NAID 120004140871

Related Links

• Suicide Gene Therapy - Emerging Mesothelioma Treatment ...

Suicide gene therapy shows promise for the treatment of mesothelioma by causing cancerous cells to self-destruct. ... Suicide gene therapy is an experimental treatment option that shows great potential as a targeted therapy for ...

• Suicide Gene Therapy: Methods and Reviews - Google Books

The first comprehensive review of both the theory and practice of suicide gene therapy. The authors cover all the major aspects of suicide gene therapy, including the design and use of vectors in gene transduction, various enzyme and ...

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★リンクテーブル★

リンク元	「自殺遺伝子治療」「自殺遺伝子療法」
関連記事	「therapy」

「自殺遺伝子治療」

　　[★]

英

suicide gene therapy

関

自殺遺伝子療法

「自殺遺伝子療法」

　　[★]

英

suicide gene therapy

関

自殺遺伝子治療

「therapy」

　　[★]

• n.

• 治療、治療法、療法

関

care、cure、curing、practice、psychotherapy、regimen、remediation、remedy、therapeutic、treat、treatment、treatment protocol