WordNet

the act of destroying yourself; "his insistence was pure self-destruction"
(used as a combining form) relating to--of or by or to or from or for--the self; "self-knowledge"; "self-proclaimed"; "self-induced"
your consciousness of your own identity (同)ego
a person considered as a unique individual; "ones own self"
the termination of something by causing so much damage to it that it cannot be repaired or no longer exists (同)devastation
an event (or the result of an event) that completely destroys something (同)demolition, wipeout

PrepTutorEJDIC

(他人と区別して)『自己』,自分,自身 / 〈C〉(人・物の)本質,個性;性格の一面 / 〈U〉私利,私欲,私心 / 同じ材料でできた,共ぎれの
『破壊』[行為] / 破壊された状態,破滅,絶滅 / 破壊手段,破壊をもたらすもの

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/17 23:38:26」(JST)

wiki en

In human context, self-destructive behavior is a widely used phrase that conceptualizes certain kinds of destructive acts as belonging to the self. It also has the property that it characterizes certain kinds of self-inflicted acts as destructive. The term comes from objective psychology, wherein all apparent self-inflicted harm or abuse toward oneself is treated as a collection of actions, and therefore as a pattern of behavior.

Acts of "self-destruction" may be merely metaphorical ("social suicide") or literal (suicide). Generally speaking, self-destructive actions may be deliberate, born of impulse, or developed as a habit. The term however tends to be applied toward self-destruction that are potentially habit-forming or addictive, and are thus potentially fatal.

Suicide
Self-harm
Eating disorders^{[medical citation needed]}
Substance abuse

Forms

Self-destructive behavior may be used as a coping mechanism, when things get to be 'too much'. For example, faced with a pressing scholastic assessment, someone may choose to sabotage their work rather than cope with the stress. This would make submission of (or passing) the assessment impossible, but remove the worry associated with it.

Self-destructive behavior may also manifest itself in an active attempt to drive away other people. For example, they may fear that they will "mess up" a relationship. Rather than deal with this fear, socially self-destructive individuals engage in annoying or alienating behavior, so that others will reject them first.

More obvious forms of self-destruction are eating disorders, alcohol abuse, drug addictions, sex addiction, self-injury, and suicide attempts.

An important aspect of self-destructive behavior is the inability to handle the stress stemming from an individual's lack of self-confidence - for example in a relationship, whether the other person is truly faithful ("how can they love someone like me?"); at work or school, whether the realization of assignments and deadlines is possible ("there is no way I can complete all my work on time"). Self-destructive people usually lack healthier coping mechanisms, like asserting personal boundaries. As a result, they tend to feel that showing they are incompetent is the only way to untangle themselves from demands.

Successful individuals may self-destructively sabotage their own achievements; this may stem from a feeling of anxiety, unworthiness, or from an impulsive desire to repeat the "climb to the top."

Self-destructive behavior is often considered to be synonymous with self-harm, but this is not accurate. Self-harm is an extreme form of self-destructive behavior, but it may appear in many other guises.

Causes

In some cases it could be explained by a person having learned dysfunctional patterns earlier in life. Separation from parents and attachment disorders have been linked with self-destructive behavior, and with failure to engage in self-care behavior.^[1]

References

^ Childhood origins of self-destructive behavior. van der Kolk BA, Perry JC, Herman JL, Am J Psychiatry 1991 Dec; 148(12):1665-71

UpToDate Contents

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English Journal

The role of intramolecular self-destruction of reactive metabolic intermediates in determining toxicity.

Svennebring A1.
Journal of applied toxicology : JAT.J Appl Toxicol.2016 Apr;36(4):483-500. doi: 10.1002/jat.3248. Epub 2015 Nov 6.
When reactive centers are formed in chemical conversions, intermolecular reactions tend to dominate over intramolecular alternatives whenever both alternatives are possible. Hence, when reactive metabolites are formed from xenobiotics, intramolecular quenching by moieties adjacent to a toxicophore m
PMID 26542997

A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells.

Fan H1, Yan G1, Zhao Z1, Hu X1, Zhang W1, Liu H1, Fu X1,2, Fu T1, Zhang XB3, Tan W4,5.
Angewandte Chemie (International ed. in English).Angew Chem Int Ed Engl.2016 Mar 24. doi: 10.1002/anie.201510748. [Epub ahead of print]
Photodynamic therapy (PDT) has been applied in cancer treatment by utilizing reactive oxygen species to kill cancer cells. However, a high concentration of glutathione (GSH) is present in cancer cells and can consume reactive oxygen species. To address this problem, we report the development of a ph
PMID 27010667

A G4·K+ hydrogel that self-destructs.

Plank TN1, Davis JT1.
Chemical communications (Cambridge, England).Chem Commun (Camb).2016 Mar 17. [Epub ahead of print]
A G4-quartet based hydrogel formed by self-assembly of borate esters of 5'-deoxy-5'-iodoguanosine (5'-IG 2) undergoes in situ cyclization to give 5'-deoxy-N3,5'-cycloguanosine (5'-cG ). Formation of 5'-cG causes self-destruction of the gel. This intramolecular cyclization can be used to release nucl
PMID 26984819

Japanese Journal

『ビルマの日々』における主人公フローリと「動物」表象(東北英文学研究)

山口梓
英文学研究. 支部統合号 6, 81-88, 2014-01-20
… This episode reinforces her cruelty and tacitly shows Flory's own self-destruction in that those killed animals can be seen as himself. …
NAID 110009817015

術後早期に局所再発と肺・骨転移し予後不良であった悪性葉状腫瘍の1例

山口絢音,露木茂,川口展子,有本明
日本臨床外科学会雑誌 75(5), 1193-1197, 2014
葉状腫瘍は乳房腫瘍中の0.5％以下と稀で，25％が悪性である．われわれは急速増大し，術後短期間に再発・転移した悪性葉状腫瘍の1例を経験した．<BR>症例は38歳女性．1カ月前から急速増大する左乳房腫瘤を自覚，皮膚自壊部から出血し当院受診，緊急入院となった．針生検で葉状腫瘍が疑われ，左乳房切除・植皮術を施行．病理診断は悪性葉状腫瘍であった．術後1カ月で局所再発，多発肺転移出現．症状緩和目 …
NAID 130004706261

エチレングリコール抽出/ICP発光分析法と熱重量分析法の併用による鉄鋼スラグ中のフリーCaOの定量

加藤美佐,波理竜也,齋藤伸吾 [他],渋川雅美
鉄と鋼 100(3), 340-345, 2014
… However, the slags may contain appreciable amounts of free lime (CaO) that can cause expansive self-destruction by reactions with water and carbon dioxide in the air. …
NAID 130003395123

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