stratified squamous epithelium

WordNet

1. membranous tissue covering internal organs and other internal surfaces of the body (同)epithelial_tissue
2. deposited or arranged in horizontal layers; "stratified rock" (同)bedded

PrepTutorEJDIC

1. 上皮[組織](生物体の表皮・血管内壁など)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/09/03 16:02:36」(JST)

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Stratified squamous epithelium
H&E stain of biopsy of normal esophagus showing the stratified squamous cell epithelium
Section of the human skin showing the stratified squamous epithelial surface, referred to as the epidermis. The layer of keratin here is named the stratum corneum
Anatomical terminology [edit on Wikidata]

This article is one of a series on
Epithelia
Squamous epithelial cell
Simple Stratified
Columnar epithelial cell
Simple Stratified Pseudostratified
Cuboidal epithelial cell
Simple Stratified
Specialised epithelia
Olfactory Respiratory Intestinal Transitional Germinal female male
Other
Table of epithelia of human organs

A stratified squamous epithelium consists of squamous (flattened) epithelial cells arranged in layers upon a basal membrane. Only one layer is in contact with the basement membrane; the other layers adhere to one another to maintain structural integrity. Although this epithelium is referred to as squamous, many cells within the layers may not be flattened; this is due to the convention of naming epithelia according to the cell type at the surface. In the deeper layers, the cells may be columnar or cuboidal.. There are no intercellular spaces. This type of epithelium is well suited to areas in the body subject to constant abrasion, as it is the thickest and layers can be sequentially sloughed off and replaced before the basement membrane is exposed. It forms the outermost layer of the skin and the inner lining of the mouth, esophagus, and vagina.

Keratinization

Non-keratinized

Non-keratinized surfaces must be kept moist by bodily secretions to prevent them from drying out.

Examples of non-keratinized stratified squamous epithelium include cornea (see also corneal epithelium), lining mucosa of oral cavity, esophagus, anal canal, foreskin, vagina, and the internal portion of the lips.

Note that even non-keratinized surfaces, consisting as they do of keratinocytes, will have a minor superficial keratinized layer of varying thickness, depending on the age of the epithelium and the damage it has experienced.

Keratinized

Keratinized surfaces are protected from abrasion by keratin and kept hydrated and protected from dehydration by glycolipids produced in the stratum granulosum.

Examples of keratinized stratified squamous epithelium include epidermis of the palm of the hand and sole of the foot, and the masticatory mucosa.

Gallery

• Epithelium

• Micrograph of normal stratified squamous epithelium (right of image) and the metaplasic epithelium of Barrett's esophagus (left of image). Alcian blue stain.

References

UpToDate Contents

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• 1. 子宮頚部および膣細胞診：結果の解釈 cervical and vaginal cytology interpretation of results
• 2. 外陰癌：臨床症状、診断、および病理 vulvar cancer clinical manifestations diagnosis and pathology
• 3. 頭頸部腫瘍の病理 pathology of head and neck neoplasms
• 4. 皮膚扁平上皮細胞癌および基底細胞癌における局所および遠隔転移の評価 evaluation for locoregional and distant metastases in cutaneous squamous cell and basal cell carcinoma
• 5. 女性における尿道癌 urethral cancer in women

English Journal

• Expression of TMEM166 Protein in Human Normal and Tumor Tissues.

• Xu D, Yang F, He H, Hu J, Lv X, Ma D, Chen YY.Source*Key Laboratory of Medical Immunology, Ministry of Health †Peking University Center for Human Disease Genomics ‡Department of Thoracic Surgery, Peking University People's Hospital §Department of Pathology, School of Basic Medical Sciences, Peking University, Beijing, China.
• Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry.Appl Immunohistochem Mol Morphol.2013 Dec;21(6):543-52. doi: 10.1097/PAI.0b013e31824e93d1.
• Transmembrane protein 166 (TMEM166) is a novel human regulator involved in both autophagy and apoptosis. In this study, we generated a specific rabbit polyclonal antibody against human TMEM166 and assessed the expression of this protein in various human normal and tumor tissue samples by tissue micr
• PMID 22495369

• Complementary expression and repulsive signaling suggest that EphB2 and ephrin-B1 are possibly involved in epithelial boundary formation at the squamocolumnar junction in the rodent stomach.

• Ogawa K, Saeki N, Igura Y, Hayashi Y.SourceLaboratory of Veterinary Anatomy, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-Ourai-Kita, Izumisano, Osaka, 598-8531, Japan, kogawa@vet.osakafu-u.ac.jp.
• Histochemistry and cell biology.Histochem Cell Biol.2013 Dec;140(6):659-75. doi: 10.1007/s00418-013-1129-2. Epub 2013 Jul 24.
• Eph receptors and ephrin ligands are cell-cell communication molecules with well-defined roles in cell adhesion, migration, and tissue boundary formation. However, their expression levels in the squamocolumnar epithelial junction region at the distal esophagus are completely unknown. We examined Eph
• PMID 23881165

• Transpterygoid Stent Placement for Management of a Recurrent Infratemporal Fossa Epidermoid Cyst: A Technical Note.

• Ibrahim T, Ackerman PD, Welch KC, Prabhu VC.SourceDepartment of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, United States.
• Journal of neurological surgery reports.J Neurol Surg Rep.2013 Dec;74(2):123-128. Epub 2013 Nov 6.
• Epidermoid cysts (ECs) are benign congenital cysts that typically develop from misplaced stratified squamous epithelium during neural tube closure. They are most commonly encountered in the cerebellopontine angle, the fourth ventricle, and the region of the sella turcica. Recurrence of an EC or regr
• PMID 24294567

Japanese Journal

• 症例 陰茎縫線腫 : 重層円柱上皮壁の扁平上皮化生による増大と考えられた1例

• 白井 明,朝比奈 昭彦
• 皮膚科の臨床 53(13), 1936-1939, 2011-12
• NAID 40019086526

• 小児に発生した声門下顆粒細胞腫例

• 大村 学,辻川 敬裕,渡邉 大樹,四ノ宮 隆,柴田 敏章,馬場 均,高原 哲夫,久 育男
• 耳鼻咽喉科臨床 104(10), 715-719, 2011-10-01
• … Histologically, the tumor showed the proliferation of large cells with abundant eosinophilic granular cytoplasm and oval nuclei and a surface entirely covered by stratified squamous epithelium. …
• NAID 10029659210

Related Links

• Stratified Squamous Epithelium | histologyolm.stevegallik.org

Stratified Squamous Epithelium A stratified squamous epithelium consists of more than one (typically many) layers, or strata, of epithelial cells (see figure). The basal layer of epithelial cells are small and cuboidal-to-columnar; the ...

• Stratified Squamous Epithelium - virtuallabs.html

Stratified squamous epithelium Stratified epithelium is also a lining tissue which provides protection for underlying tissues. Stratified epithelia are normally found in places where there is a great deal of wear and tear. Frequently, the ...

Related Pictures

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★リンクテーブル★

リンク元	「上皮」「重層扁平上皮」
関連記事	「squamous」「squamous epithelium」

「上皮」

　　[★]

英

epithelium, (pl.)epithelia

関

上皮組織、消化器系#上皮の移行、呼吸器の上皮の移行

上皮の分類

• 単層扁平上皮 simple squamous epithelium
• 単層立方上皮 simple cuboidal epithelium
• 単層円柱上皮 simple columnar epithelium
• 多列上皮 pseudostratified epithelium
• 重層扁平上皮 stratified squamous epithelium
• 重層立方上皮 stratified cuboidal epithelium
• 重層円柱上皮 stratified columnar epithelium
• 移行上皮 transitional epithelium

「重層扁平上皮」

　　[★]

英

()

英

stratified squamous epithelium

英

stratified squamous epithelium

「squamous」

　　[★]

• adj.

• 扁平上皮の, 鱗片状の

関

squamous epithelium

「squamous epithelium」

　　[★] 扁平上皮

関

squamous