- 関
- somatic hypermutation、somatic mutation
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism (同)genetic mutation, chromosomal_mutation
- a change or alteration in form or qualities
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- 変化,俸転 / (生物の)突然変異;その変種
- 身体の / 体腔(たいこう)の / 体細胞の
UpToDate Contents
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English Journal
- Immune deficiency augments the prevalence of p53 loss of heterozygosity in spontaneous tumors but not bi-directional loss of heterozygosity in bone marrow progenitors.
- Shetzer Y1, Napchan Y1, Kaufman T1, Molchadsky A1, Tal P1, Goldfinger N1, Rotter V1.
- International journal of cancer.Int J Cancer.2017 Mar 15;140(6):1364-1369. doi: 10.1002/ijc.30554.
- p53 loss of heterozygosity (LOH) is a frequent event in tumors of somatic and Li-Fraumeni syndrome patients harboring p53 mutation. Here, we focused on resolving a possible crosstalk between the immune-system and p53 LOH. Previously, we reported that p53 heterozygous bone-marrow mesenchymal progenit
- PMID 28008605
- Splenic diffuse red pulp lymphoma has a distinct pattern of somatic mutations amongst B-cell malignancies.
- Traverse-Glehen A1,2, Verney A2, Gazzo S2,3, Jallades L2,4, Chabane K2,4, Hayette S2,4, Coiffier B2,5, Callet-Bauchu E2,3, Ffrench M4, Felman P2,4, Berger F1,2, Baseggio L2,4, Salles G2,5.
- Leukemia & lymphoma.Leuk Lymphoma.2017 Mar;58(3):666-675. doi: 10.1080/10428194.2016.1196813. Epub 2016 Jun 27.
- Splenic Diffuse Red Pulp Lymphoma (SDRPL) has been recently introduced as a provisional entity but differential diagnosis with other splenic lymphomas is needed to be clarified since the therapeutic approaches are distinct. Recently described recurrent mutations or CD180 expression appear useful for
- PMID 27347751
- Analysis of ARMC5 expression in human tissues.
- Berthon A1, Faucz F1, Bertherat J2, Stratakis CA3.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2017 Feb 5;441:140-145. doi: 10.1016/j.mce.2016.08.018. Epub 2016 Aug 24.
- Mutations in ARMC5 gene have been recently identified as the main cause of Primary Macronodular Adrenocortical Hyperplasia (PMAH). PMAH patients have an ARMC5 germline mutation and, in addition, somatic tissue-specific mutations. This is consistent with the two-hit hypothesis of tumorigenesis and su
- PMID 27568465
Japanese Journal
- Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation
- C-X-C chemokine receptor type 4 (CXCR4) is a key receptor for chicken primordial germ cell migration
Related Links
- mutation [mu-ta´shun] 1. a permanent transmissible change in the genetic material. 2. an individual exhibiting such a change. point mutation a mutation resulting from a change in a single base pair in the DNA molecule. somatic ...
- Somatic mutation is a type of human mutation that occurs in you DNA. It causes 90-95% of cancer cases. A mutation is a change or alteration made in the gene of your cell. This kind of mutation is also called acquired because the ...
★リンクテーブル★
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- 英
- somatic hypermutation、somatic cell mutation、somatic mutation
- 関
- 体細胞変異、体細胞過剰変異、体細胞超変異
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- 関
- somatic cell mutation、somatic hypermutation
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- 関
- cell body、soma、somata、somatic cell、somatically
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細胞
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- 関
- somatic