- 関
- sarcoplasmic reticulum calcium ATPase、sarcoplasmic reticulum calcium-transporting ATPase、SERCA
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- the second compartment of the stomach of a ruminant (同)second stomach
- any fine network (especially one in the body composed of cells or blood vessels)
- a small constellation in the southern hemisphere near Dorado and Hydrus
- the cytoplasm of a striated muscle fiber
PrepTutorEJDIC
- carbonの化学記号
- Calciumの化学記号
UpToDate Contents
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English Journal
- Identification and characterization of a kunzeaol synthase from Thapsia garganica: implications for the biosynthesis of the pharmaceutical thapsigargin.
- Pickel B, Drew DP, Manczak T, Weitzel C, Simonsen HT, Ro DK.Source*Department of Biological Sciences, University of Calgary, Calgary, Canada, T2N 1N4.
- The Biochemical journal.Biochem J.2012 Dec 1;448(2):261-71. doi: 10.1042/BJ20120654.
- Thapsigargin is a major terpenoid constituent of Thapsia garganica root. Owing to its potent antagonistic effect on the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, thapsigargin has been widely used to study Ca2+ signalling and is also a potential drug for prostate cancer. Despite its importance,
- PMID 22938155
- Tropomyosin Dephosphorylation Results in Compensated Cardiac Hypertrophy.
- Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JE, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF.SourceUniversity of Cincinnati Medical Center, United States;
- The Journal of biological chemistry.J Biol Chem.2012 Nov 12. [Epub ahead of print]
- Phosphorylation of tropomyosin (Tm) has been shown to vary in mouse models of cardiac hypertrophy. Little is known about the in vivo role of Tm phosphorylation. This study examines the consequences of Tm dephosphorylation in the murine heart. Transgenic (TG) mice were generated with cardiac specif
- PMID 23148217
Japanese Journal
- 心不全・致死的不整脈における細胞内カルシウム放出異常
- 矢野 雅文
- 山口医学 63(1), 11-16, 2014-02-01
- … 分極が生じるごとにL型 Ca2+チャネル(LTCC)から少量のCa2+が流入し,その流入Ca2+がトリガーとなり筋小胞体(SR)膜上にあるCa2+放出チャネルのリアノジン受容体(RyR)からの大量のCa2+放出を引き起こす.細胞内の増加したCa2+は,収縮蛋白を活性化した後,SRのCa2+-ATPaseによりSR内に再び取り込 …
- NAID 120005435141
- 心不全・致死的不整脈における細胞内カルシウム放出異常
- 矢野 雅文
- 山口医学 63(1), 11-16, 2014
- … 生じるごとにL型 Ca2+チャネル(LTCC)から少量のCa2+が流入し,その流入Ca2+がトリガーとなり筋小胞体(SR)膜上にあるCa2+放出チャネルのリアノジン受容体(RyR)からの大量のCa2+放出を引き起こす.細胞内の増加したCa2+は,収縮蛋白を活性化した後,SRのCa2+-ATPaseによりSR内に再び …
- NAID 130004476032
- Calcium kinetics of sarcoplasmic reticulum and muscle fatigue
- Wada Masanobu,Kuratani Mai,Kanzaki Keita
- The Journal of Physical Fitness and Sports Medicine 2(2), 169-178, 2013
- … Current efforts to examine the relevant mechanisms involved in muscle fatigue are focused on Ca2+-regulation function within the active muscle cell. … The sarcoplasmic reticulum (SR) is the major organelle in muscle responsible for regulating cytosolic free Ca2+concentration. … Numerous studies have demonstrated that SR function, with respect to both Ca2+ release and uptake, is impaired after contractile activity that induces fatigue. …
- NAID 130003379952
Related Links
- Transcriptional Regulation of the Sarcoplasmic Reticulum Ca2+-ATPase Gene 群馬大学医学部第2内科 新井昌史(Masashi Arai) Summary Ca2+-ATPaseは心筋小胞体へのCa2+汲み上げを行う蛋白であり,心弛緩過程を ...
- 1. Anal Biochem. 1999 Mar 1;268(1):79-88. Measurement of sarcoplasmic reticulum Ca2+-ATPase activity and E-type Mg2+-ATPase activity in rat heart homogenates. Saborido A, Delgado J, Megías A. Department of Biochemistry ...
Related Pictures
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![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcTNXEXPRFRwmgZTRJLR6M8-8UYDBcw8xpe-VkBkhy8zERz8YS8zluGWfW2T:http://pathman.smpdb.ca/system/image_2s/390/original/SMP00367_CARVEDILOL_b.jpg%3F1250785518)
★リンクテーブル★
[★]
[★]
- 関
- reticula、reticular、reticulata
[★]
- 同
- ATP hydrolase
- 関
- アデノシン三リン酸
[★]
- 関
- sarcoplasm
[★]
カルシウム calcium