receptor-interacting protein serine-threonine kinase 2

• 受容体共役タンパク質セリンスレオニンキナーゼ2

WordNet

1. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
2. a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
3. a colorless crystalline amino acid found in protein; occurs in the hydrolysates of certain proteins; an essential component of human nutrition
4. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
5. a sweetish crystalline amino acid involved in the synthesis by the body of cysteine

PrepTutorEJDIC

1. 蛋白(たんばく)質
2. =sense organ / 受信装置

UpToDate Contents

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• 1. 複合免疫不全 combined immunodeficiencies
• 2. インスリン受容体の構造および機能 structure and function of the insulin receptor
• 3. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
• 4. 血小板生物学 platelet biology
• 5. 重度複合型免疫不全（SCID）：特定の欠損 severe combined immunodeficiency scid specific defects

English Journal

• Proteogenomics connects somatic mutations to signalling in breast cancer.

• Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, Wang X, Qiao JW, Cao S, Petralia F, Kawaler E, Mundt F, Krug K, Tu Z, Lei JT, Gatza ML, Wilkerson M, Perou CM, Yellapantula V, Huang KL, Lin C, McLellan MD, Yan P, Davies SR, Townsend RR, Skates SJ, Wang J, Zhang B, Kinsinger CR, Mesri M, Rodriguez H, Ding L, Paulovich AG, Fenyö D, Ellis MJ, Carr SA; NCI CPTAC.
• Nature.Nature.2016 Jun 2;534(7605):55-62. doi: 10.1038/nature18003.
• Somatic mutations have been extensively characterized in breast cancer, but the effects of these genetic alterations on the proteomic landscape remain poorly understood. Here we describe quantitative mass-spectrometry-based proteomic and phosphoproteomic analyses of 105 genomically annotated breast
• PMID 27251275

• CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.

• Hrdinka M1, Fiil BK1, Zucca M1, Leske D1, Bagola K1, Yabal M2, Elliott PR3, Damgaard RB1, Komander D3, Jost PJ2, Gyrd-Hansen M4.
• Cell reports.Cell Rep.2016 Mar 29;14(12):2846-58. doi: 10.1016/j.celrep.2016.02.062. Epub 2016 Mar 17.
• Innate immune signaling relies on the deposition of non-degradative polyubiquitin at receptor-signaling complexes, but how these ubiquitin modifications are regulated by deubiquitinases remains incompletely understood. Met1-linked ubiquitin (Met1-Ub) is assembled by the linear ubiquitin assembly com
• PMID 26997266

• Hydrogen sulfide diminishes the levels of thymic stromal lymphopoietin in activated mast cells.

• Han NR1, Moon PD1, Jeong HJ2, Kim HM3.
• Archives of dermatological research.Arch Dermatol Res.2016 Mar;308(2):103-13. doi: 10.1007/s00403-016-1619-x. Epub 2016 Jan 20.
• Bamboo salt (BS) is a Korean traditional type of salt and has been reported to have therapeutic effects on allergic inflammation. Thymic stromal lymphopoietin (TSLP) aggravates inflammation in the pathogenesis of allergic reactions, such as allergic rhinitis (AR). To confirm an active compound of BS
• PMID 26791024

Japanese Journal

• Association of the RIP2 Gene with Childhood Atopic Asthma

• Nakashima Kazuko,Hirota Tomomitsu,Suzuki Yoichi,Akahoshi Mitsuteru,Shimizu Makiko,Jodo Aya,Doi Satoru,Fujita Kimie,Ebisawa Motohiro,Yoshihara Shigemi,Enomoto Tadao,Shirakawa Taro,Kishi Fumio,Nakamura Yusuke,Tamari Mayumi
• Allergology International 55(1), 77-83, 2006
• … Background: Receptor-interacting protein (RIP)-2 is a serine/threonine kinase containing a caspase recruitment domain (CARD) that is involved in the Toll-like receptor-signaling pathway. …
• NAID 130004476885

Related Links

• Ripk2 - Receptor-interacting serine/threonine-protein kinase 2 ...

Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 ...

• RIPK2 - Receptor-interacting serine/threonine-protein kinase 2 ...

Receptor-interacting serine/threonine-protein kinase 2 Gene RIPK2 Organism Homo sapiens (Human) Status Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein level i Function i , , , [] [] []: ...

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★リンクテーブル★

リンク元	「受容体共役タンパク質セリンスレオニンキナーゼ2」
関連記事	「threonine kinase」「kinase」「serine」「threonine」「interacting protein」

「受容体共役タンパク質セリンスレオニンキナーゼ2」

　　[★]

英

receptor-interacting protein serine-threonine kinase 2

「threonine kinase」

　　[★]

スレオニンキナーゼ、トレオニンキナーゼ

関

protein-serine-threonine kinase、serine kinase、serine-threonine kinase、serine-threonine protein kinase

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「serine」

　　[★] セリン

関

L-serine、S、Ser

　

「threonine」

　　[★] スレオニン L-threonine T Thr 　

「interacting protein」

　　[★]

• 相互作用タンパク質