WordNet

existing in possibility; "a potential problem"; "possible uses of nuclear power" (同)possible
the inherent capacity for coming into being (同)potentiality, potency

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1. ループス腎炎患者における腎生検の適応 indications for renal biopsy in patients with lupus nephritis
2. 難治性または再発性のびまん性または巣状増殖性ループス腎炎の治療 therapy of resistant or relapsing diffuse or focal proliferative lupus nephritis
3. びまん性または巣状増殖性ループス腎炎の治療 therapy of diffuse or focal proliferative lupus nephritis
4. 心筋活動電位および抗不整脈剤の作用 myocardial action potential and action of antiarrhythmic drugs
5. 膜性ループス腎炎の臨床的特徴および治療 clinical features and therapy of membranous lupus nephritis

The genotoxic effects of anti-cancer drug gossypol on human lymphocytes and its mitigation by melatonin.

Rao MV1, Narechania MB1.
Drug and chemical toxicology.Drug Chem Toxicol.2016 Oct;39(4):357-61. doi: 10.3109/01480545.2015.1039646. Epub 2016 Apr 12.
PURPOSE OF STUDY: To determine melatonin as a potential natural antioxidant to mitigate the genotoxic effects of promising anti-cancer drug gossypol in human lymphocytes.INTRODUCTION: Gossypol, is a polyphenolic compound naturally occurring in cotton seed, was originally identified as a male contrac
PMID 27071859

Systematic comparison of the functional physico-chemical characteristics and biocidal activity of microbial derived biosurfactants on blood-derived and breast cancer cells.

Akiyode O1, George D1, Getti G1, Boateng J2.
Journal of colloid and interface science.J Colloid Interface Sci.2016 Oct 1;479:221-33. doi: 10.1016/j.jcis.2016.06.051. Epub 2016 Jun 22.
HYPOTHESIS: The cytotoxicity of biosurfactants on cell membranes may be influenced by composition of their hydrophilic head and hydrophobic tails. It is hypothesised that they form mixed micelles which exert a detergent-like effect that disrupts the plasma membrane. The functional physico-chemical a
PMID 27390853

A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening.

Skardal A1,2,3, Devarasetty M4,5, Forsythe S4, Atala A4,5, Soker S4,5,6.
Biotechnology and bioengineering.Biotechnol Bioeng.2016 Sep;113(9):2020-32. doi: 10.1002/bit.25950. Epub 2016 Mar 8.
Current animal and 2-D cell culture models employed in metastasis research and drug discovery remain poor mimics of human cancer physiology. Here we describe a "metastasis-on-a-chip" system allowing real time tracking of fluorescent colon cancer cells migrating from hydrogel-fabricated gut construct
PMID 26888480

Involvement of MicroRNA-133a in the Development of Arteriosclerosis Obliterans of the Lower Extremities via RhoA Targeting

Li Yongxin,Ouyang Mao,Shan Zhen,Ma Jieyi,Li Jie,Yao Chen,Zhu Zhengrong,Zhang Longjuan,Chen Lianzhou,Chang Guangqi,Wang Shenming,Wang Wenjian
Journal of Atherosclerosis and Thrombosis 22(4), 424-432, 2015
… Of note, the overexpression of RhoA in the HASMCs attenuated the anti-proliferative and anti-migratory effects of miR-133a.Conclusions: Our data indicate that miR-133a regulates the functions of HASMCs by targeting RhoA and may be involved in the pathogenesis of ASO. … These findings may lead to the development of potential therapeutic targets for ASO of the lower extremities. …
NAID 130005066049

Grace Suto Eriko,Mabuchi Yo,Suzuki Nobuharu,Koyanagi Asuka,Kawabata Yoshiko,Ogata Yusuke,Ozeki Nobutake,Nakagawa Yusuke,Muneta Takeshi,Sekiya Ichiro,Akazawa Chihiro
Inflammation and Regeneration 35(2), 078-085, 2015
… The current study compared the differentiation/proliferative potency of purified mouse MSCs (CD45-/ TER119-/PDGFRα+/ Sca-1+ … Both cell migration and proliferation were significantly higher in PαS vs. WBM cells, indicating the enhanced differentiation potential of PαS cells for the mesenchymal lineage, and suggesting that WBM cell heterogeneity may regulate and limit the stemness of their MSC progeny. …
NAID 130005063945

The canine epiphyseal-derived mesenchymal stem cells are comparable to bone marrow derived-mesenchymal stem cells

CHANG Ya-Pei,HONG Hsuan-Ping,LEE Yen-Hua,LIU I-Hsuan
Journal of Veterinary Medical Science 77(3), 273-280, 2015
… Mesenchymal stem cells (MSCs) hold great potential in cell therapy and have attracted increasing interests in a wide range of biomedical sciences. … The successful rate for EMSC isolation is significantly higher compared to BMSC isolation, while the other properties of the isolated MSCs including the clonogenicity, proliferative potentials and molecular phenotypes were not discernibly different between the MSCs established by the two methods. …
NAID 130005060995