ポリADPリボース
WordNet
- the 1st letter of the Roman alphabet (同)a
- the blood group whose red cells carry the A antigen (同)type_A, group A
- a pentose sugar important as a component of ribonucleic acid
- in the Christian era; used before dates after the supposed year Christ was born; "in AD 200" (同)A.D., anno_Domini
PrepTutorEJDIC
- answer / ampere
- リボース(リボ核酸の加水分解によって得られる五炭糖)
- =polytechnic
UpToDate Contents
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English Journal
- Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage.
- Chang YT1, Huang CY2, Li KT3, Li RN4, Liaw CC5, Wu SH6, Liu JR7, Sheu JH8, Chang HW9.
- Archives of oral biology.Arch Oral Biol.2016 Jun;66:147-54. doi: 10.1016/j.archoralbio.2016.02.019. Epub 2016 Mar 2.
- OBJECTIVE: Sinuleptolide, a soft corals-derived bioactive norditerpenoid, is a marine natural product with a potent anti-inflammatory effect. We evaluate the potential anti-oral cancer effects of sinuleptolide and investigate the possible mechanisms involved.DESIGNS: Cell viability, cell cycle, apop
- PMID 26954095
- Decreased DNA repair gene XRCC1 expression is associated with radiotherapy-induced acute side effects in breast cancer patients.
- Batar B1, Guven G2, Eroz S3, Bese NS3, Guven M4.
- Gene.Gene.2016 May 10;582(1):33-7. doi: 10.1016/j.gene.2016.01.040. Epub 2016 Jan 27.
- DNA repair plays a critical role in response to ionizing radiation (IR) and developing of radiotherapy induced normal tissue reactions. In our study, we investigated the association of radiotherapy related acute side effects, with X-ray repair cross complementing group 1 (XRCC1) and Poly (ADP-ribose
- PMID 26826460
- What Is the Place of PARP Inhibitors in Ovarian Cancer Treatment?
- Liu JF1, Matulonis UA2.
- Current oncology reports.Curr Oncol Rep.2016 May;18(5):29. doi: 10.1007/s11912-016-0515-z.
- Poly-ADP-ribose polymerase (PARP) inhibitors have been one of the most exciting developments in the treatment of ovarian cancer in recent years. Demonstration of anti-cancer activity has led to the European Medicines Agency (EMA) approval of the PARP inhibitor (PARPi) olaparib as maintenance therapy
- PMID 26984416
Japanese Journal
- Poly(ADP-ribose) polymerase 1 activation links ischemic acute kidney injury to interstitial fibrosis
- Yoon Sang Pil,Kim Jinu
- The journal of physiological sciences 65(1), 105-111, 2015-01
- NAID 40020323622
- The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells
- , , ,
- The Journal of Toxicological Sciences 40(3), 349-363, 2015
- … In this study, we investigated ATO sensitization and detoxification effect of the Poly (ADP ribose) polymerase-1 (PARP-1) inhibitor 4-Amino-1,8-naphthalimide (4AN) in the hepatocellular carcinoma cell line HepG2. …
- NAID 130005068414
- Basic helix-loop-helix transcription factor DEC1 regulates the cisplatin-induced apoptotic pathway of human esophageal cancer cells
- , , , , , , ,
- Biomedical Research 36(2), 89-96, 2015
- … DEC1 knockdown by siRNA in TE 10 decreased the amount of cleaved poly (ADP-ribose) polymerase (PARP) after treatment with CDDP, whereas DEC2 knockdown had no effects on the amount of cleaved PARP in both the presence and absence of CDDP. …
- NAID 130005065284
Related Links
- poly（ADP-Ribose）（pADPr）は，poly（ADP-Ribose）polymerase（PARP）によって合成され，NAD＋を基質としてヒストンなどの核タンパク質に付加されるポリマーで，クロマチン構造の制御やDNA修復に関与することが報告されて ...
- Figure 1. Poly(ADP-ribose) structure. Poly(ADP-ribose) polymerases (PARPs) cleave the glycosidic bond of NAD + between nicotinamide and ribose followed by the covalent modification of mainly glutamate residues of acceptor ...
★リンクテーブル★
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- 英
- poly adenosine diphosphate ribose、poly ADP-ribose、poly ADPR
- 同
- ポリADPリボース
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- 関
- poly adenosine diphosphate ribose、poly ADP-ribose
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ポリADPリボースポリメラーゼ
- 関
- PARP、poly ADP-ribose polymerase
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- 関
- multi
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リボース
- 関
- D-ribose