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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/22 21:58:11」(JST)

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1. 男性性機能不全の治療 treatment of male sexual dysfunction
2. 収縮能障害による心不全における強心剤 inotropic agents in heart failure due to systolic dysfunction
3. 成人における肺高血圧症の治療 treatment of pulmonary hypertension in adults
4. 心不全患者において使用をさけるべき、または慎重に使用するべき薬 drugs that should be avoided or used with caution in patients with heart failure
5. 喘息におけるテオフィリン使用 theophylline use in asthma

Daniels CM1, Thirawatananond P2, Ong SE3, Gabelli SB2,4,5, Leung AK1,5.
Scientific reports.Sci Rep.2015 Dec 16;5:18271. doi: 10.1038/srep18271.
ADP-ribosylation refers to the transfer of the ADP-ribose group from NAD(+) to target proteins post-translationally, either attached singly as mono(ADP-ribose) (MAR) or in polymeric chains as poly(ADP-ribose) (PAR). Though ADP-ribosylation is therapeutically important, investigation of this protein
PMID 26669448

Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2α cleavage complexes in human cells.

Borda MA1, Palmitelli M1, Verón G1, González-Cid M1, de Campos Nebel M2.
Mutation research.Mutat Res.2015 Nov;781:37-48. doi: 10.1016/j.mrfmmm.2015.09.003. Epub 2015 Sep 14.
Tyrosyl-DNA-phosphodiesterase 1 (TDP1) is a DNA repair enzyme that removes irreversible protein-linked 3' DNA complexes, 3' phosphoglycolates, alkylation damage-induced DNA breaks, and 3' deoxyribose nucleosides. In addition to its extended spectrum of substrates, TDP1 interacts with several DNA dam
PMID 26421495

Tyrosyl-DNA Phosphodiesterase I Inhibitors from the Australian Plant Macropteranthes leichhardtii.

Tian LW1, Feng Y1, Tran TD1, Shimizu Y2, Pfeifer T2, Forster PI3, Quinn RJ1.
Journal of natural products.J Nat Prod.2015 Jul 24;78(7):1756-60. doi: 10.1021/acs.jnatprod.5b00211. Epub 2015 Jul 7.
Mass-directed isolation of the CH2Cl2/MeOH extract from the bark of an Australian plant, Macropteranthes leichhardtii, resulted in the purification of a new phenylpropanoid glucoside, macropteranthol (1), together with four known analogues (2-5). The structure of compound 1 was elucidated by NMR and
PMID 26149757