末梢血赤血球形態
WordNet
- smear with blood, as in a hunting initiation rite, where the face of a person is smeared with the blood of the kill
- temperament or disposition; "a person of hot blood"
- people viewed as members of a group; "we need more young blood in this organization"
- the fluid (red in vertebrates) that is pumped through the body by the heart and contains plasma, blood cells, and platelets; "blood carries oxygen and nutrients to the tissues and carries away waste products"; "the ancients believed that blood was the sea
- related to the key issue but not of central importance; "a peripheral interest"; "energy is far from a peripheral issue in the economy"; "peripheral issues"
- (computer science) electronic equipment connected by cable to the CPU of a computer; "disk drives and printers are important peripherals" (同)computer peripheral, peripheral device
- on or near an edge or constituting an outer boundary; the outer area; "Russias peripheral provinces"; "peripheral suburbs"
- the branch of geology that studies the characteristics and configuration and evolution of rocks and land forms (同)geomorphology
- the admissible arrangement of sounds in words (同)sound structure, syllable structure, word structure
- studies of the rules for forming admissible words
- the branch of biology that deals with the structure of animals and plants
PrepTutorEJDIC
- 『血』,『血』液 / 流血(bloodshed);殺人 / 気質,気性,血気,血潮 / 『血統』,血縁(kinship);生まれ,家柄;《the~》王家の血統 / (人種・出身国の)系 / 〈人〉‘に'初めての経験をさせる / 〈猟犬〉‘に'初めて獲物を血を味わわせる
- 周囲の; 周辺（装置）の・末梢的な・重要でない; （...に比べて）瑣末な (to); 【医】末端部の; コンピュータの周辺装置
- 形態学(生物の構造の研究) / 形態論,語形論(言語の形態の研究)
- 純血の,純種の / 《複合語を作って》「…の血(性質)を持った」の意を表す
- 赤血球
UpToDate Contents
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English Journal
- Ultrastructure of novel thrombocytes in the dog snapper Lutjanus jocu.
- Azevedo C1, Matos P, Rocha S, Matos E, Oliveira E, Al-Quraishy S, Casal G.Author information 1Laboratory of Cell Biology, Institute of Biomedical Sciences (ICBAS/UP), University of Porto, 4050-313, Porto, Portugal; Laboratory of Pathology, Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR/UP), University of Porto, 4050-123, Porto, Portugal; Zoology Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia.AbstractMyxosporean cysts containing spores of Henneguya sp. were observed in the gills of the dog snapper Lutjanus jocu. Adjacent to the cysts were capillaries, allowing observation of peripheral blood cells. Numerous white blood cells displaying uncommon cytoplasmic projections were observed amongst the erythrocytes. Their morphology allowed them to be identified as thrombocytes (TCs). Each TC displayed 18-26 cytoplasmic projections, most of which were in close proximity to erythrocytes. At their apical end, each cytoplasmic projection presented an ellipsoidal vacuole (c. 0·6 µm × 0·3 µm) from which a secretory tubule, 0·3-0·4 µm long and c. 120 nm in total diameter, extended towards the periphery of the TC plasmalemma and fused with the cellular membrane. From this opening, contents of vacuoles were apparently released into the lumen of the capillaries. Other vacuoles with similar features, and containing an electron-lucent matrix, were observed in the cytoplasm of the TC. This is the first description of fish TC with these ultrastructural features and organization, which suggest that they perform a secretory function.
- Journal of fish biology.J Fish Biol.2014 Apr;84(4):865-71. doi: 10.1111/jfb.12261. Epub 2014 Mar 7.
- Myxosporean cysts containing spores of Henneguya sp. were observed in the gills of the dog snapper Lutjanus jocu. Adjacent to the cysts were capillaries, allowing observation of peripheral blood cells. Numerous white blood cells displaying uncommon cytoplasmic projections were observed amongst the e
- PMID 24602039
- Imaging flow cytometry for automated detection of hypoxia-induced erythrocyte shape change in sickle cell disease.
- van Beers EJ1, Samsel L, Mendelsohn L, Saiyed R, Fertrin KY, Brantner CA, Daniels MP, Nichols J, McCoy JP, Kato GJ.Author information 1Hematology Branch and the Electron Microscopy Core Facility and Flow Cytometry Core Facility, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.AbstractIn preclinical and early phase pharmacologic trials in sickle cell disease, the percentage of sickled erythrocytes after deoxygenation, an ex vivo functional sickling assay, has been used as a measure of a patient's disease outcome. We developed a new sickle imaging flow cytometry assay (SIFCA) and investigated its application. To perform the SIFCA, peripheral blood was diluted, deoxygenated (2% oxygen) for 2 hr, fixed, and analyzed using imaging flow cytometry. We developed a software algorithm that correctly classified investigator tagged "sickled" and "normal" erythrocyte morphology with a sensitivity of 100% and a specificity of 99.1%. The percentage of sickled cells as measured by SIFCA correlated strongly with the percentage of sickle cell anemia blood in experimentally admixed samples (R = 0.98, P ≤ 0.001), negatively with fetal hemoglobin (HbF) levels (R = -0.558, P = 0.027), negatively with pH (R = -0.688, P = 0.026), negatively with pretreatment with the antisickling agent, Aes-103 (5-hydroxymethyl-2-furfural) (R = -0.766, P = 0.002), and positively with the presence of long intracellular fibers as visualized by transmission electron microscopy (R = 0.799, P = 0.002). This study shows proof of principle that the automated, operator-independent SIFCA is associated with predictable physiologic and clinical parameters and is altered by the putative antisickling agent, Aes-103. SIFCA is a new method that may be useful in sickle cell drug development. Am. J. Hematol., 2014. © 2014 Wiley Periodicals, Inc.
- American journal of hematology.Am J Hematol.2014 Mar 1. doi: 10.1002/ajh.23699. [Epub ahead of print]
- In preclinical and early phase pharmacologic trials in sickle cell disease, the percentage of sickled erythrocytes after deoxygenation, an ex vivo functional sickling assay, has been used as a measure of a patient's disease outcome. We developed a new sickle imaging flow cytometry assay (SIFCA) and
- PMID 24585634
- Specific macrothrombocytopenia/hemolytic anemia associated with sitosterolemia.
- Wang Z1, Cao L, Su Y, Wang G, Wang R, Yu Z, Bai X, Ruan C.Author information 1Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Lab of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China.AbstractSitosterolemia (phytosterolemia) is a rare inherited sterol storage disorder, characterized by significantly elevated plasma levels of plant sterols. The clinical features of sitosterolemia are xanthomas, premature atherosclerosis, arthritis, and, occasionally, liver function impair and hematologic abnormalities. This disorder is caused by mutations of ABCG5/ABCG8 genes. We report here the clinical, laboratory, and molecular genetic features of 13 patients with sitosterolemia from eight unrelated families who had specific hematologic problems of macrothrombocytopenia, hemolytic anemia, and splenomegaly besides the major clinical manifestations. The peripheral blood films showed some unique features: large platelets surrounded by a circle of vacuoles, and various abnormal erythrocyte shapes, especially stomatocyte. According to these distinct changes of blood cell morphology, we identified two sitosterolemia patients who lacked the classical clinical phenomena. All the patients had been misdiagnosed with immune thrombocytopenia (ITP), Evans syndrome, or secondary ITP with delay being 28.8 years between symptom onset and correct diagnosis. These results indicate that sitosterolemia is certainly not as rare as originally thought. The phenomena of macrothrombocytopenia/hemolysis might represent a new platelet disorder. Plasma plant sterols and ABCG5/ABCG8 genes should be analyzed when such hematologic abnormalities are unexplained.
- American journal of hematology.Am J Hematol.2014 Mar;89(3):320-4. doi: 10.1002/ajh.23619.
- Sitosterolemia (phytosterolemia) is a rare inherited sterol storage disorder, characterized by significantly elevated plasma levels of plant sterols. The clinical features of sitosterolemia are xanthomas, premature atherosclerosis, arthritis, and, occasionally, liver function impair and hematologic
- PMID 24166850
Japanese Journal
- Ovalocytosis without band 3 gene 27-bp deletion and malaria infection
- Reactive Changes in Breast Carcinoma and in Axillary Lymph Nodes
- Reactive Changes in Breast Carcinoma and in Axillary Lymph Nodes
Related Links
- This page includes the following topics and synonyms: Erythrocyte Morphology on Peripheral Smear, Erythrocyte Morphology, Red Blood Cell Morphology, Macrocyte, Microcyte, Spherocyte, Elliptocyte, Schistocyte, Acanthocyte ...
- Automated digital cell morphology. Systems which locate, identify and pre-classify white blood cells for the hematology field. ... 6-8 microns Cell without nucleus Slightly reddish cytoplasm,clearer towards the center No granules
★リンクテーブル★
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- 英
- peripheral red blood cell morphology, peripheral blood erythrocyte morphology
- 関
- 末梢血、赤血球
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- 末梢性の、末梢の、末梢神経性の、末梢神経の、周辺性の
- 関
- peripheral nerve、peripherally、peripheric、periphery
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- 関
- form、morphologic、morphological、topology
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赤血球 red blood cells
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血液