WordNet

the 9th letter of the Roman alphabet (同)i
precursor of pepsin; stored in the stomach walls and converted to pepsin by hydrochloric acid in the stomach

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1. 胃癌スクリーニング gastric cancer screening
2. 胃炎および胃障害の分類と診断 classification and diagnosis of gastritis and gastropathy
3. 胃酸分泌の生理学 physiology of gastric acid secretion
4. 栄養の吸収および吸収不良の機序 mechanisms of nutrient absorption and malabsorption
5. 消化性潰瘍：遺伝的、環境的、心理的危険因子および病因 peptic ulcer disease genetic environmental and psychological risk factors and pathogenesis

Long-term dynamics of gastric biomarkers after eradication of Helicobacter pylori infection.

Daugule I1, Ruskule A, Moisejevs G, Rudzite D, Jonaitis L, Janciauskas D, Kiudelis G, Kupcinskas L, Leja M.
European journal of gastroenterology & hepatology.Eur J Gastroenterol Hepatol.2015 May;27(5):501-5. doi: 10.1097/MEG.0000000000000308.
BACKGROUND: Secretion of pepsinogen I (PgI), pepsinogen II (PgII), fasting gastrin-17 (fG-17) and stimulated gastrin-17 (sG-17) changes after Helicobacter pylori eradication. Few data are available on the long-term dynamics of gastric biomarkers after H. pylori eradication.The aim of this study was
PMID 25822857

Increase in the Prevalence of Atrophic Gastritis Among Adults Age 35 to 44 Years Old in Northern Sweden Between 1990 and 2009.

Song H1, Held M2, Sandin S3, Rautelin H4, Eliasson M5, Söderberg S6, Hallmans G7, Engstrand L8, Nyrén O3, Ye W3.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.Clin Gastroenterol Hepatol.2015 Apr 6. pii: S1542-3565(15)00366-3. doi: 10.1016/j.cgh.2015.04.001. [Epub ahead of print]
BACKGROUND & AIMS: Atrophic corpus gastritis (ACG) is believed to be an early precursor of gastric adenocarcinoma. We aimed to investigate trends of ACG in Northern Sweden, from 1990 through 2009, and to identify possible risk factors.METHODS: We randomly selected serum samples collected from 52
PMID 25857683

Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK-438 (vonoprazan), a novel potassium-competitive acid blocker, in healthy male subjects.

Jenkins H1, Sakurai Y, Nishimura A, Okamoto H, Hibberd M, Jenkins R, Yoneyama T, Ashida K, Ogama Y, Warrington S.
Alimentary pharmacology & therapeutics.Aliment Pharmacol Ther.2015 Apr;41(7):636-48. doi: 10.1111/apt.13121. Epub 2015 Feb 23.
BACKGROUND: TAK-438 (vonoprazan) is a potassium-competitive acid blocker that reversibly inhibits gastric H(+) , K(+) -ATPase.AIM: To evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of TAK-438 in healthy Japanese and non-Japanese men.METHODS: In two Phase I, randomised, doub
PMID 25707624

高野伸一,大高雅彦,三浦和夫,松井啓,山口達也,植竹智義,大塚博之,佐藤公,榎本信幸,渡辺英伸
日本消化器内視鏡学会雑誌 = Gastroenterological endoscopy 54(8), 2225-2231, 2012-08-20
77歳男性．十二指腸球部に20mmで頂部に陥凹を有す粘膜下腫瘍様隆起を認め，内視鏡的粘膜切除術を施行した．病理組織学的には幽門腺型腺腫ないしBrunner腺腺腫に類似していた．免疫染色では腫瘍の構成細胞は，50％が頸部粘液型細胞で，40％が幽門腺型細胞で，腫瘍露出部の表層が5％ほどの胃小窩型細胞であった．さらに少数の壁細胞も混在していた．胃型形質であるにも関わらず，CDX2やCD10に陽性を示した …
NAID 10031122056