- 関
- microsatellite、microsatellite marker、microsatellite repeat、short tandem repeat、tetranucleotide repeat
WordNet
- do over; "They would like to take it over again" (同)take_over
- an event that repeats; "the events today were a repeat of yesterdays" (同)repetition
- to say again or imitate; "followers echoing the cries of their leaders" (同)echo
- to say, state, or perform again; "She kept reiterating her request" (同)reiterate, ingeminate, iterate, restate, retell
PrepTutorEJDIC
- 〈自分がすでに一度言ったこと)‘を'『繰り返して言う』 / 〈他人の言ったこと〉‘を'おうむ返しに言う;…‘を'他の人に繰り返して言う / …‘を'『暗記して言う』,暗唱する / …‘を'繰り返して行う(do again) / (食べたあとで)〈食物の〉味が残る / 〈小数が〉循環する / 繰り返すこと,反復すること / 繰り返されるもの,(公演の)再演;(番組の)再放送 / 反復楽節;反復記号(∥: :∥)
- 繰り返して言われる(行われる)
UpToDate Contents
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- 1. 帝王切開の再施行 repeat cesarean delivery
- 2. 遺伝性運動失調の概要 overview of the hereditary ataxias
- 3. 前立腺生検 prostate biopsy
- 4. 冠動脈バイパス術後の後期再発性狭心症 late recurrent angina pectoris after coronary artery bypass graft surgery
- 5. 脊髄小脳変性症 the spinocerebellar ataxias
English Journal
- Microsatellite markers for direct genotyping of the crayfish plague pathogen Aphanomyces astaci (Oomycetes) from infected host tissues.
- Grandjean F1, Vrålstad T2, Diéguez-Uribeondo J3, Jelić M4, Mangombi J5, Delaunay C5, Filipová L6, Rezinciuc S3, Kozubíková-Balcarová E7, Guyonnet D8, Viljamaa-Dirks S9, Petrusek A7.Author information 1Laboratoire Ecologie et Biologie des Interactions, Equipe: Ecologie, Evolution, Symbiose, Université de Poitiers, UMR CNRS 7267, 40 av. du Recteur Pineau, F-86022 Poitiers Cedex, France. Electronic address: frederic.grandjean@univ-poitiers.fr.2Norwegian Veterinary Institute, N-0106 Oslo, Norway; Microbial Evolution Research Group (MERG), Department of Biosciences, University of Oslo, N-0316 Oslo, Norway.3Departamenta de Micologia, Real Jardín Botánico CSIC, Plaza Murillo 2, 28014 Madrid, Spain.4University of Zagreb, Faculty of Science, Division of Biology, Department of Zoology, Rooseveltov trg 6, 10000 Zagreb, Croatia.5Laboratoire Ecologie et Biologie des Interactions, Equipe: Ecologie, Evolution, Symbiose, Université de Poitiers, UMR CNRS 7267, 40 av. du Recteur Pineau, F-86022 Poitiers Cedex, France.6Laboratoire Ecologie et Biologie des Interactions, Equipe: Ecologie, Evolution, Symbiose, Université de Poitiers, UMR CNRS 7267, 40 av. du Recteur Pineau, F-86022 Poitiers Cedex, France; Charles University in Prague, Faculty of Science, Department of Ecology, Viničná 7, CZ-12844 Prague, Czech Republic.7Charles University in Prague, Faculty of Science, Department of Ecology, Viničná 7, CZ-12844 Prague, Czech Republic.8Laboratoire Signalisation et Transports Ioniques Membranaires STIM ERL 7368, 1 rue George Bonnet, F 86022 Poitiers, France.9OIE Reference Laboratory for Crayfish Plague, Finnish Food Safety Authority Evira, Neulaniementie 4, FI-70210 Kuopio, Finland.AbstractAphanomyces astaci is an invasive pathogenic oomycete responsible for the crayfish plague, a disease that has devastated European freshwater crayfish. So far, five genotype groups of this pathogen have been identified by applying random amplified polymorphic DNA analysis on axenic cultures. To allow genotyping of A. astaci in host tissue samples, we have developed co-dominant microsatellite markers for this pathogen, tested them on pure cultures of all genotype groups, and subsequently evaluated their use on tissues of (1) natural A. astaci carriers, i.e., North American crayfish species, and (2) A. astaci-infected indigenous European species from crayfish plague outbreaks. Out of over 200 potential loci containing simple sequence repeat (SSR) motifs identified by 454 pyrosequencing of SSR-enriched library, we tested 25 loci with highest number of repeats, and finally selected nine that allow unambiguous separation of all known RAPD-defined genotype groups of A. astaci from axenic cultures. Using these markers, we were able to characterize A. astaci strains from DNA isolates from infected crayfish tissues when crayfish had a moderate to high agent level according to quantitative PCR analyses. The results support the hypothesis that different North American crayfish hosts carry different genotype groups of the pathogen, and confirm that multiple genotype groups, including the one originally introduced to Europe in the 19th century, cause crayfish plague outbreaks in Central Europe. So far undocumented A. astaci genotype seems to have caused one of the analysed outbreaks from the Czech Republic. The newly developed culture-independent approach allowing direct genotyping of this pathogen in both axenic cultures and mixed genome samples opens new possibilities in studies of crayfish plague pathogen distribution, diversity and epidemiology.
- Veterinary microbiology.Vet Microbiol.2014 Jun 4;170(3-4):317-24. doi: 10.1016/j.vetmic.2014.02.020. Epub 2014 Feb 24.
- Aphanomyces astaci is an invasive pathogenic oomycete responsible for the crayfish plague, a disease that has devastated European freshwater crayfish. So far, five genotype groups of this pathogen have been identified by applying random amplified polymorphic DNA analysis on axenic cultures. To allow
- PMID 24631110
- Gene conversion violates the stepwise mutation model for microsatellites in y-chromosomal palindromic repeats.
- Balaresque P1, King TE, Parkin EJ, Heyer E, Carvalho-Silva D, Kraaijenbrink T, de Knijff P, Tyler-Smith C, Jobling MA.Author information 1UMR5288 CNRS/UPS-AMIS-Université Paul Sabatier, Toulouse, France; Department of Genetics, University of Leicester, Leicester, UK.AbstractThe male-specific region of the human Y chromosome (MSY) contains eight large inverted repeats (palindromes), in which high-sequence similarity between repeat arms is maintained by gene conversion. These palindromes also harbor microsatellites, considered to evolve via a stepwise mutation model (SMM). Here, we ask whether gene conversion between palindrome microsatellites contributes to their mutational dynamics. First, we study the duplicated tetranucleotide microsatellite DYS385a,b lying in palindrome P4. We show, by comparing observed data with simulated data under a SMM within haplogroups, that observed heteroallelic combinations in which the modal repeat number difference between copies was large, can give rise to homoallelic combinations with zero-repeats difference, equivalent to many single-step mutations. These are unlikely to be generated under a strict SMM, suggesting the action of gene conversion. Second, we show that the intercopy repeat number difference for a large set of duplicated microsatellites in all palindromes in the MSY reference sequence is significantly reduced compared with that for nonpalindrome-duplicated microsatellites, suggesting that the former are characterized by unusual evolutionary dynamics. These observations indicate that gene conversion violates the SMM for microsatellites in palindromes, homogenizing copies within individual Y chromosomes, but increasing overall haplotype diversity among chromosomes within related groups.
- Human mutation.Hum Mutat.2014 May;35(5):609-17. doi: 10.1002/humu.22542.
- The male-specific region of the human Y chromosome (MSY) contains eight large inverted repeats (palindromes), in which high-sequence similarity between repeat arms is maintained by gene conversion. These palindromes also harbor microsatellites, considered to evolve via a stepwise mutation model (SMM
- PMID 24610746
- Characterization and high cross-species transferability of microsatellite markers from the floral transcriptome of Aspidistra saxicola (Asparagaceae).
- Huang D1, Zhang Y, Jin M, Li H, Song Z, Wang Y, Chen J.Author information 1Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, Institute of Biodiversity Science, School of Life Sciences, Fudan University, Shanghai 200433, China.AbstractRecent studies utilizing transcriptome sequences generated by next-generation sequencing (NGS) technologies have demonstrated the ability to rapidly detect and characterize thousands of gene-based microsatellites from different plants. However, these simple sequence repeats (SSRs) were seldom used directly to test interspecific transferability in the populations of closely related species. Aspidistra Ker-Gawl. is a monocot genus with high species richness and diversity in flower structure, but its fresh floral materials are not easy to obtain. Until now, little is known about genetic background in the species of Aspidistra, quite apart from the fearful reduction of their natural habitats. In this study, the floral transcriptome of Aspidistra saxicola was obtained using NGS. Based on these data, a total of 5527 SSRs were identified in the unigenes. Among these SSRs, the proportions of di- and tri-nucleotide repeats were quite close (49.6% verse 46.8%), and the most tri-nucleotide repeats were AGG/CCT followed by AAG/CTT and AGC/GCT in A. saxicola, showing distinct differences with other angiosperm species. To assess genetic diversity in the species of Aspidistra, 48 SSR loci were tested in four available populations of A. elatior. The results revealed that more than a third of the loci were polymorphic. The majority of these primers could be amplified in 24 species representing the main clades of Aspidistra. The primer subsets from transcriptome data proved highly useful for detecting polymorphisms in the related species, supporting the finding that NGS is an efficient approach to molecular marker development at both intra- and interspecies levels, especially in endangered nonmodel species.
- Molecular ecology resources.Mol Ecol Resour.2014 May;14(3):569-77. doi: 10.1111/1755-0998.12197. Epub 2013 Nov 29.
- Recent studies utilizing transcriptome sequences generated by next-generation sequencing (NGS) technologies have demonstrated the ability to rapidly detect and characterize thousands of gene-based microsatellites from different plants. However, these simple sequence repeats (SSRs) were seldom used d
- PMID 24286608
Japanese Journal
- アポリポプロテイン(a)遺伝子発現はTTTTA反復配列よりも5'-ハプロタイプによって制御される
- 山形大学紀要. 医学 : 山形医学 32(1), 17-28, 2014-02-15
- NAID 110009684538
- Pentanucleotide repeat-primed PCR for genetic diagnosis of spinocerebellar ataxia type 31
- Journal of human genetics 57(12), 807-808, 2012-12-01
- NAID 10031145890
- Mining of EST-SSR markers in clam Meretrix meretrix larvae from 454 shotgun transcriptome
- Genes & genetic systems 86(3), 197-205, 2011-06-25
- NAID 10029678951
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★リンクテーブル★
| リンク元 | 「microsatellite」「short tandem repeat」「五ヌクレオチド反復」「microsatellite marker」「microsatellite repeat」 |
| 関連記事 | 「repeat」「repeated」 |
「microsatellite」
- (数塩基の短いモチーフが繰り返すDNA配列)イクロサテライト、ミクロサテライト
- 関
- microsatellite marker、microsatellite repeat、pentanucleotide repeat、short tandem repeat、tetranucleotide repeat
「short tandem repeat」
- (遺伝子)短いタンデム反復、ミクロサテライト
- 関
- microsatellite、microsatellite marker、microsatellite repeat、pentanucleotide repeat、STR、tetranucleotide repeat
- 同
- STR
- 同
- STR
「五ヌクレオチド反復」
「microsatellite marker」
- 関
- microsatellite、microsatellite repeat、pentanucleotide repeat、short tandem repeat、tetranucleotide repeat
「microsatellite repeat」
- 関
- microsatellite、microsatellite marker、pentanucleotide repeat、short tandem repeat、tetranucleotide repeat
「repeat」
- n.
- v.
- 反復する、繰り返す
- 関
- iteration、recursion、reiterate、reiteration、reiterative、repeatedly、repetition、repetitive、repetitively、replicate
「repeated」
- adj.
- 頻回の
- 関
- frequent