出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/22 21:57:48」(JST)
| Names | |
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| IUPAC name
2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide[1]
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Other names
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| Identifiers | |
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CAS Number
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16485-10-2 N 81-13-0 R N |
| 3DMet | B00882 |
| ATC code | A11HA30 D03AX03, S01XA12 |
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Beilstein Reference
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1724945, 1724947 R |
| ChEBI | CHEBI:27373 N |
| ChEMBL | ChEMBL1200979 N |
| ChemSpider | 4516 Y 115991 R N |
| EC Number | 240-540-6 |
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InChI
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| Jmol interactive 3D | Image Image |
| KEGG | D03726 Y |
| MeSH | dexpanthenol |
| PubChem | 4678 131204 R |
| RTECS number | ES4316500 |
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SMILES
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| UNII | 1O6C93RI7Z Y |
| Properties | |
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Chemical formula
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C9H19NO4 |
| Molar mass | 205.25 g·mol−1 |
| Appearance | Colourless liquid[contradictory] |
| Density | 1.2 g mL−1 (at 20 °C) |
| Melting point | 66 to 69 °C (151 to 156 °F; 339 to 342 K) |
| log P | −0.989 |
| Acidity (pKa) | 13.033 |
| Basicity (pKb) | 0.964 |
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Refractive index (nD)
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1.499 |
| Hazards | |
| NFPA 704 |
1
1
0
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| Lethal dose or concentration (LD, LC): | |
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LD50 (Median dose)
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10,100 mg kg−1 (intraperitoneal, mouse); 15,000 mg kg−1 (oral, mouse) |
| Related compounds | |
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Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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| N verify (what is YN ?) | |
| Infobox references | |
Panthenol (pantothenol) is the alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5. In organisms it is quickly oxidized to pantothenate. Panthenol is a highly viscous transparent liquid at room temperature, but salts of pantothenic acid (for example sodium pantothenate) are powders (typically white). It is soluble in water, alcohol and propylene glycol, soluble in ether and chloroform, and slightly soluble in glycerin.
Panthenol comes in two enantiomers, D and L. Only D-panthenol (dexpanthenol) is biologically active, however both forms have moisturizing properties. For cosmetic use, panthenol comes either in D form, or as a racemic mixture of D and L (DL-panthenol).
Panthenol's expanded chemical formula is: HO-CH2-C(CH3)2-CH(OH)-CONH-CH2CH2CH2-OH.
In cosmetics and personal-care products, panthenol is a humectant, emollient, and moisturizer. It binds to the hair shaft readily; so, it is a common component of commercial shampoos and hair conditioners (in concentrations of 0.1-1.0%). It coats the hair and seals its surface[citation needed], lubricating the hair shaft and giving it a shiny appearance. It is also recommended by many tattoo artists as a post-tattooing moisturising cream.
Panthenol draws moisture from the atmosphere and readily binds to water molecules. When applied to the hair panthenol will help to moisturize it and give it a shine and gloss. For this reason it has become a very popular ingredient in shampoos and conditioners.
In ointments, panthenol is an effective skin penetrator.[2] It is sometimes mixed with allantoin, in concentrations of up to 2-5%, and is used for treatment of sunburns, mild burns and minor skin disorders.[citation needed] It improves hydration, reduces itching and inflammation of the skin, and accelerates epidermal wounds' rate of healing.[2]
If ingested, panthenol is metabolized to pantothenic acid.
Other names for panthenol include:
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| リンク元 | 「パンテノール」 |
| 拡張検索 | 「dexpanthenol」 |
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