酸化的バースト
WordNet
- move suddenly, energetically, or violently; "He burst out of the house into the cool night"
- break open or apart suddenly and forcefully; "The dam burst" (同)bust
- come open suddenly and violently, as if from internal pressure; "The bubble burst" (同)split, break_open
- a sudden flurry of activity (often for no obvious reason); "a burst of applause"; "a fit of housecleaning" (同)fit
- emerge suddenly; "The sun burst into view"
- remove the burrs from (同)burr
- seed vessel having hooks or prickles (同)burr
- small bit used in dentistry or surgery (同)burr
- taking place in the presence of oxygen; "oxidative glycolysis"; "oxidative rancidity"
PrepTutorEJDIC
- 『破裂する』,爆発する / 〈つぼみが〉ほころびる / 《通例進行形で》(…で)はちきれそうにいっぱいである《+『with』+『名』》 / 『急に(…)する』 / …'を'破裂させる,爆発させる,破る / (…の)『破裂』,爆発《+『of』+『名』》 / (…の)『突発』《+『of』+『名』》
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/07/30 13:11:12」(JST)
[Wiki en表示]
Respiratory burst (sometimes called oxidative burst) is the rapid release of reactive oxygen species (superoxide radical and hydrogen peroxide) from different types of cells.
Usually it denotes the release of these chemicals from immune cells, e.g., neutrophils and monocytes, as they come into contact with different bacteria or fungi. They are also released from the ovum of higher animals after the ovum has been fertilized. These substances can also be released from plant cells.
Respiratory burst plays an important role in the immune system. It is a crucial reaction that occurs in phagocytes to degrade internalized particles and bacteria.
NADPH oxidase, an enzyme family in the vasculature (in particular, in vascular disease), produces superoxide, which spontaneously recombines with other molecules to produce reactive free radicals. The superoxide reacts with NO, resulting in the formation of peroxynitrite, reducing the bioactive NO needed to dilate terminal arterioles, feed arteries and resistance arteries. Superoxide anion, peroxynitrite, and other reactive oxygen species also lead to pathology via peroxidation of proteins and lipids, and via activation of redox sensitive signaling cascades and protein nitrosylation. NADPH oxidase activation has been suggested to depend on prior PKC activation.[1] Myeloperoxidase uses the reactive oxygen species hydrogen peroxide to produce hypochlorous acid. Many vascular stimuli, including all those known to lead to insulin resistance, activate NADPH oxidase via both increased gene expression and complex activation mechanisms.
To combat infections, immune cells use NADPH oxidase to reduce O2 to oxygen free radical and then H2O2. Neutrophils and monocytes utilize myeloperoxidase to further combine H2O2 with Cl- to produce hypochlorite, which plays a role in destroying bacteria. Absence of NADPH oxidase will prevent the formation of reactive oxygen species and will result in chronic granulomatous disease.
References
- ^ Inoguchi T, Sonta T, Tsubouchi H, Etoh T, Kakimoto M, Sonoda N, Sato N, Sekiguchi N, Kobayashi K, Sumimoto H, Utsumi H, Nawata H (2003). "Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidase". J. Am. Soc. Nephrol. 14 (8 Suppl 3): S227–32. DOI:10.1097/01.ASN.0000077407.90309.65. PMID 12874436. Free full text
External links
- Respiratory+burst at the US National Library of Medicine Medical Subject Headings (MeSH)
UpToDate Contents
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English Journal
- A role for melatonin in maintaining the pro- and anti-inflammatory balance by influencing leukocyte migration and apoptosis in carp.
- Kepka M1, Szwejser E1, Pijanowski L1, Verburg-van Kemenade BM2, Chadzinska M3.
- Developmental and comparative immunology.Dev Comp Immunol.2015 Nov;53(1):179-90. doi: 10.1016/j.dci.2015.07.011. Epub 2015 Jul 15.
- Melatonin is responsible for the synchronization of many physiological processes, including the immune response. Here we focus on the expression of melatonin MT1 receptors in/on leukocytes, and on the effects of melatonin administration on the inflammatory processes of carp. For the first time, we s
- PMID 26188098
- Stem bark and flower extracts of Vismia cauliflora are highly effective antioxidants to human blood cells by preventing oxidative burst in neutrophils and oxidative damage in erythrocytes.
- Ribeiro AB1, Berto A, Ribeiro D, Freitas M, Chisté RC, Visentainer JV, Fernandes E.
- Pharmaceutical biology.Pharm Biol.2015 Nov;53(11):1691-8. doi: 10.3109/13880209.2014.1001407. Epub 2015 Apr 14.
- CONTEXT: Vismia cauliflora A.C.Sm. [Hypericaceae (Clusiaceae)] is an Amazonian plant traditionally used by indigenous population to treat dermatosis and inflammatory processes of the skin. Previous research on V. cauliflora extracts suggests its potential to neutralize cellular oxidative damages rel
- PMID 25868622
- Inhibitory effect of plant phenolics on fMLP-induced intracellular calcium rise and chemiluminescence of human polymorphonuclear leukocytes and their chemotactic activity in vitro.
- Nowak PJ1, Zasowska-Nowak A, Bialasiewicz P, de Graft-Johnson J, Nowak D, Nowicki M.
- Pharmaceutical biology.Pharm Biol.2015 Nov;53(11):1661-70. doi: 10.3109/13880209.2014.1001403. Epub 2015 Apr 9.
- CONTEXT: Polymorphonuclear leukocytes (PMNs) produce oxidants, contributing to systemic oxidative stress. Diets rich in plant polyphenols seem to decrease the risk of oxidative stress-induced disorders including cardiovascular disease.OBJECTIVE: The objective of this study was to examine the in vitr
- PMID 25856712
Japanese Journal
- Evaluation of Neutrophil Function during Hemodialysis Treatment in Healthy Dogs under Anesthesia with Sevoflurane
- SHIMAMURA Shunsuke,KIMURA Ken,KATAYAMA Masaaki,MASHITA Tadahisa,MAEDA Kenichi,KOBAYASHI Saori,SATO Reeko,YASUDA Jun
- Journal of Veterinary Medical Science 76(11), 1539-1543, 2014
- … Isolated neutrophils were used to assess neutrophil adhesion, phagocytosis and the oxidative burst. …
- NAID 130004677729
- 柔道稽古後の筋損傷と好中球活性酸素種産生能の関連について
- 工藤 久,八重垣 誠,高橋 一平 [他],Umeda Takashi,Sawada Kaori,Okubo Noriyuki,Yamamoto Yousuke,Nakaji Shigeyuki
- 弘前醫學 64(2/3/4), 176-185, 2014
- … and the major neutrophil immune functions such as oxidative burst activity (OBA) and phagocytic activity (PA) were measured in 39 male university judoists before(pre value) and after 2 hours of unified exercise loading. …
- NAID 110009758630
- Isolation and characterization of an asparagine-rich protein that regulates hypersensitive cell death-mediated resistance in Nicotiana plants
- Komori Daisuke,Nishihara Masahiro,Takahashi Akiko [他],GUPTA Meenu,YOSHIOKA Hirofumi,MIZUMOTO Hiroyuki,OHNISHI Kouhei,HIKICHI Yasufumi,KIBA Akinori
- Plant biotechnology 29(3), 293-300, 2012-06-25
- … Expression of HR-related hin1 and onset of the oxidative burst were delayed in NbARP-silenced plants, and induction of myelin basic kinase activity was reduced. …
- NAID 10030804810
Related Links
- The white blood cell oxidative burst kills bacteria. HOME Contents... Cell Biology Microbiology Immunology Microscopy Interactive... Cell Models HowBig Mitosis Cell Cycle Meiosis Cell Cams Puzzles Quizzes Free... Study Aids
- res·pi·ra·to·ry burst the marked increase in metabolic activity that occurs in phagocytes and certain other cells following binding of particles resulting in ... The oxidative burst in hemocytes of lobsters sampled in June of both years ...
Related Pictures
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★リンクテーブル★
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- 英
- oxidative burst
BPT.39
- 酸素消費↑、グリコーゲン分解↑、グルコース酸化↑、活性酸素種の産生↑
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- 英
- myeloperoxidase, MPO
- 関
- oxidative burst、ペルオキシダーゼ染色
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- 英
- oxidative burst
- 関
- 呼吸性バースト、酸化的バースト
[★]
- 関
- break out、bursting、explode、explosion、rash、rupture
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- (クリ・ゴボウなどの)いが。いがのある植物。くっつくもの。厄介者。(医)バー(ドリル)(外科・歯科用の小さなドリル)。バードリルの穿子
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- 関
- oxidatively
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- 関
- burst