WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- cell that functions in the breakdown and resorption of bone tissue
- causing motion or action or change (同)actuating
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
UpToDate Contents
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- 1. 悪性腫瘍の高カルシウム血症 hypercalcemia of malignancy
- 2. 多発性骨髄腫の病理生物学 pathobiology of multiple myeloma
- 3. 高カルシウム血症の原因 etiology of hypercalcemia
- 4. 肺癌の危険因子、病理、および臨床症状の概要 overview of the risk factors pathology and clinical manifestations of lung cancer
- 5. 癌性疼痛症候群の概要 overview of cancer pain syndromes
English Journal
- Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells.
- Noll JE1, Williams SA, Tong CM, Wang H, Quach JM, Purton LE, Pilkington K, To LB, Evdokiou A, Gronthos S, Zannettino AC.
- Haematologica.Haematologica.2014 Jan;99(1):163-71. doi: 10.3324/haematol.2013.090977. Epub 2013 Aug 9.
- Multiple myeloma is an incurable hematologic cancer characterized by the clonal proliferation of malignant plasma cells within the bone marrow. Numerous studies suggest that the myeloma plasma cells occupy and alter the stromal tissue of the bone marrow as a means of enhancing their survival and gro
- PMID 23935020
- Increased serum levels of MIP-1alpha correlate with bone disease and angiogenic cytokines in patients with multiple myeloma.
- Tsirakis G1, Roussou P, Pappa CA, Kolovou A, Vasilokonstantaki C, Miminas I, Kyriakaki S, Alegakis A, Alexandrakis MG.
- Medical oncology (Northwood, London, England).Med Oncol.2014 Jan;31(1):778. doi: 10.1007/s12032-013-0778-2. Epub 2013 Nov 26.
- Many cytokines possess variable roles in the pathogenesis of multiple myeloma. Macrophage inflammatory protein-1alpha (MIP-1alpha) is an osteoclast-activating factor with a major role in myeloma bone disease. The aim of the study was to examine its participation in the angiogenic process of the dise
- PMID 24277416
- Osteoblast and osteoclast crosstalks: from OAF to Ephrin.
- Tamma R1, Zallone A.
- Inflammation & allergy drug targets.Inflamm Allergy Drug Targets.2012 Jun;11(3):196-200.
- The maintenance of bone homeostasis is tightly controlled, and largely dependent upon cellular communication between osteoclasts and osteoblasts, and the coupling of bone resorption to bone formation. This tight coupling is essential for the correct function and maintenance of the skeletal system, r
- PMID 22280242
Japanese Journal
- A bone substitute with high affinity for vitamin D-binding protein―relationship with niche of osteoclasts
- Ikeda Tohru,Kasai Michiyuki,Tatsukawa Eri,Kamitakahara Masanobu,Shibata Yasuaki,Yokoi Taishi,Nemoto Takayuki K.,Ioku Koji
- Journal of Cellular and Molecular Medicine 18(1), 170-180, 2014-01
- … Previously, we developed hydroxyapatite (HA) composed of rod-shaped particles using applied hydrothermal methods (HHA), and it revealed mild biodegradability and potent osteoclast homing activity. … However, DBP-macrophage activating factor, which is generated by the digestion of sugar chains of DBP, stimulated osteoclastogenesis. …
- NAID 120005372470
- Positive Expression of Macrophage Inflammatory Protein-1α and -1β in a Patient with Diffuse Large B-cell Lymphoma Accompanied by Hypercalcemia and Multiple Osteolysis
- Kobayashi Yujin,Hatta Yoshihiro,Hirabayashi Yukio [他],HOJO Atsuko,TANAKA Toshitake,TAKEI Kazuhiro,ISHIZUKA Hikari,SUGITANI Masahiko,AIZAWA Shin,TAKEUCHI Jin
- 日大醫學雜誌 70(2), 112-115, 2011-04-01
- NAID 10028265301
- Positive Expression of Macrophage Inflammatory Protein-1α and -1β in a Patient with Diffuse Large B-cell Lymphoma Accompanied by Hypercalcemia and Multiple Osteolysis
- Kobayashi Yujin,Hatta Yoshihiro,Hirabayashi Yukio,Hojo Atsuko,Tanaka Toshitake,Takei Kazuhiro,Ishizuka Hikari,Sugitani Masahiko,Aizawa Shin,Takeuchi Jin
- 日大医学雑誌 70(2), 112-115, 2011
- … There have been no reports demonstrating the protein expression of osteoclast-activating factors in such cases. …
- NAID 130004548861
Related Links
- He named it lymphocyte-activating factor (LAF) because it was a lymphocyte mitogen. It was not ... factor (HSP), catabolin, hemopoetin-1 (H-1), endogenous pyrogen (EP), osteoclast-activating factor (OAF), and proteolysis-inducing factor ( PIF).
- Bone destruction is mediated by factors produced or induced by tumor cells that stimulate formation and activation of osteoclasts, the normal bone-resorbing cells . Local bone destruction also occurs in patients with osteoblastic metastases and ...
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★リンクテーブル★
| リンク元 | 「破骨細胞活性化因子」「OAF」 |
| 関連記事 | 「fact」「factor」「activating factor」 |
「破骨細胞活性化因子」
「OAF」
[★] 破骨細胞活性化因子 osteoclast activating factor
「fact」
- n.
「factor」
- n.