WordNet
- used to express refusal or denial or disagreement etc or especially to emphasize a negative statement; "no, you are wrong"
- a negative; "his no was loud and clear"
- referring to the degree to which a certain quality is present; "he was no heavier than a child" (同)no more
- not in any degree or manner; not at all; "he is no better today"
- quantifier; used with either mass nouns or plural count nouns for indicating a complete or almost complete lack or zero quantity of; "we have no bananas"; "no eggs left and no money to buy any"; "have you no decency?"; "did it with no help"; "Ill get you there in no time"
- of or relating to or designating narcotics; "narcotic addicts"; "narcotic stupor"
- a drug that produces numbness or stupor; often taken for pleasure or to reduce pain; extensive use can lead to addiction
- inducing stupor or narcosis; "narcotic drugs" (同)narcotizing, narcotising
- inducing mental lethargy; "a narcotic speech" (同)soporiferous, soporific
- a medicine used to relieve pain (同)anodyne, painkiller, pain pill
- capable of relieving pain; "the anodyne properties of certain drugs"; "an analgesic effect" (同)analgetic, anodyne
- the fifth of the seven canonical hours; about 3 p.m.
PrepTutorEJDIC
- 《名詞の前に置いて》『一つも』(『一人も,少しも』)・・・『ない』 / 《補語につけて》『決して・・・でない』 / 《省略文で》・・・なし;・・・お断り / 《話》少ししか(あまり)・・・ない / (肯定の問いに対して)『いいえ』;(否定の問いに対して)はい,ええ / 《not, norの前に挿入して》『いや』,否 / 《形容詞の前に置その形容詞を否定して》…どころではない / 《比較級の前に置いて》ちっとも…でない,…と全く同じ / 《… or no の形で》…であってもなくても / 《驚き・困惑・不信などを表して》とんでもない / 《単数形で》『拒否』,「『いいえ』」という返事 / 《複数形で》反対[投]票
- 麻酔性の / 《名詞の前にのみ用いて》麻薬の / 麻酔剤,麻薬
- 鎮痛の / 鎮痛剤
UpToDate Contents
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- 1. 慢性疼痛の治療の概要 overview of the treatment of chronic pain
- 2. 癌疼痛のマネージメント：鎮痛補助剤（鎮痛剤） cancer pain management adjuvant analgesics coanalgesics
- 3. 高齢者における持続痛の治療 treatment of persistent pain in older adults
- 4. 周術期の投薬マネージメント perioperative medication management
- 5. 危篤状態の成人患者における疼痛管理 pain control in the critically ill adult patient
English Journal
- Celecoxib modifies glomerular basement membrane, mesangium and podocytes in OVE26 mice, but ibuprofen is more detrimental.
- Nasrallah R, Robertson SJ, Karsh J, Hébert RL.SourceDepartment of Cellular and Molecular Medicine, Kidney Research Centre, University of Ottawa, Ottawa, ON, Canada K1H 8M5.
- Clinical science (London, England : 1979).Clin Sci (Lond).2013 Jun;124(11):685-94. doi: 10.1042/CS20120543.
- The role of COXs/PGs (cyclo-oxygenases/prostaglandins) in diabetic kidneys remains unclear. NSAIDs (non-steroidal anti-inflammatory drugs) that inhibit COXs/PGs are known for their renal toxicity, and COX-2 inhibitors worsen cardiovascular outcomes in susceptible individuals. Given the renal controv
- PMID 23305077
- Renin inhibition in the treatment of diabetic kidney disease.
- Komers R.SourceDivision of Nephrology and Hypertension, Oregon Health and Science University, Portland, OR 97239-2940, USA. komersr@ohsu.edu
- Clinical science (London, England : 1979).Clin Sci (Lond).2013 May;124(9):553-66. doi: 10.1042/CS20120468.
- Inhibition of the RAAS (renin-angiotensin-aldosterone system) plays a pivotal role in the prevention and treatment of diabetic nephropathy and a spectrum of other proteinuric kidney diseases. Despite documented beneficial effects of RAAS inhibitors in diabetic patients with nephropathy, reversal of
- PMID 23336210
Japanese Journal
- Tipepidine enhances the antinociceptive-like action of carbamazepine in the acetic acid writhing test
- Kazuaki Kawaura,Risa Miki,Yuri Urashima,Sokichi Honda,Ahmed M. Shehata,Fumio Soeda,Tetsuya Shirasaki,Kazuo Takahama,カワウラ カズアキ,ミキ リサ,ウラシマ ユリ,ホンダ ソウキチ,ソエダ フミオ,シラサキ テツヤ,タカハマ カズオ,川浦 一晃,三木 理沙,浦嶋 優里,本田 宗吉,副田 二三夫,白崎 哲哉,高濱 和夫
- European Journal of Pharmacology 651(1-3), 106-108, 2011-01-25
- … Recently, wereported that the centrally acting non-narcotic antitussive (cough suppressant drug),tipepidine produces an antidepressant-like effect in the forced swimming test, althoughthe mechanism of action appears to be quite different from that of knownantidepressants. … Prior to studying the combination oftipepidine and carbamazepine, the analgesic action of tipepidine alone was alsoexamined in mice. …
- NAID 120003020802
- 疼痛緩和医療におけるＤＤＳ 疼痛に対する皮膚適用製剤の現状と今後
- 杉林 堅次
- Drug Delivery System 26(5), 450-456, 2011
- 現在, 本邦で用いられている疼痛治癒または緩和を目的に皮膚適用されている “外用剤” と “経皮吸収型製剤” には, 大きくわけてNSAID外用剤, 局所麻酔外用剤, そしてオピオイド鎮痛薬(麻薬性鎮痛薬と非麻薬性鎮痛薬)がある. NSAID外用剤のうち, 第二世代と称すテープ剤やパップ剤は, 適用部位直下へのNSAIDsの選択移行性を可能にしたもので, DDSとしても大変成功したものと評価されて …
- NAID 130002100324
- Design and Evaluation of Bioadhesive in-Situ Nasal Gel of Ketorolac Tromethamine
- CHELLADURAI Sankar,MISHRA Madhusmita,MISHRA Brahmeshwar
- Chemical & pharmaceutical bulletin 56(11), 1596-1599, 2008-11-01
- … The present study was aimed at developing safe and effective bioadhesive gelling systems of ketorolac tromethamine, a potent non-narcotic analgesic with moderate anti-inflammatory activity for nasal systemic delivery. …
- NAID 110006968063
Related Links
- Analgesia—condition where there is relief of pain without loss of consciousness. Analgesics—agents which cause analgesia. Narcosis—a condition of CNS depression with varying degree of stupor from where the patient can be aroused with ...
- 17 Sep 2012 ... What they are: Non-narcotic analgesics are medications used to control pain and inflammation. They are available at drugstores without a prescription, or by prescription when given at higher doses. Examples include: Tylenol ...
Related Pictures
★リンクテーブル★
| リンク元 | 「非麻薬性鎮痛薬」「nonopioid analgesic」 |
| 関連記事 | 「narcotic」「n」「narcotic analgesic」「analgesic」「non」 |
「非麻薬性鎮痛薬」
麻薬拮抗性鎮痛薬とオピオイド受容体
(標準麻酔科学 第2版p.182)
| 受容体 | μ | δ | κ | |
| 作用 | μ1 | μ2 | ||
| 上脊髄性鎮痛 | 幻覚・譫妄 | 脊髄性鎮痛 | ||
| 呼吸抑制 | 呼吸促進 | 呼吸抑制 | ||
| 身体依存性 | 不快感 | 鎮静 | ||
| 徐脈 | 頻脈 | 脈拍不変 | ||
| 縮瞳 | 散瞳 | 痙攣 | ||
| モルヒネ | agonist | - | agonist | |
| ペンタゾシン | antagonist | agonist | agonist | |
| ブプレノルフィン | partial agonist | - | agonist | |
| ブトルファノール | antagonist | - | agonist | |
| ナロキソン | antagonist | antagonist | antagonist | |
「nonopioid analgesic」
「narcotic」
- n.
- 麻薬
- adj.
- 麻薬性の
- narcotic analogue
「n」
- n.
- pの前の[n]はmと記載する。synptom→symptom
「narcotic analgesic」
「analgesic」
- adj.
- 鎮痛性の
- n.
「non」
- comb form.
- 関
- un