WordNet
- a medicine used to relieve pain (同)anodyne, painkiller, pain pill
- capable of relieving pain; "the anodyne properties of certain drugs"; "an analgesic effect" (同)analgetic, anodyne
PrepTutorEJDIC
- 鎮痛の / 鎮痛剤
UpToDate Contents
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- 1. 癌疼痛の管理：鎮痛補助剤（鎮痛剤） cancer pain management adjuvant analgesics coanalgesics
- 2. 慢性疼痛の治療の概要 overview of the treatment of chronic pain
- 3. オピオイドの使用および依存の治療 treatment of opioid use and dependence
- 4. 進行性前立腺癌における骨転移の管理 management of bone metastases in advanced prostate cancer
- 5. 成人における急性副鼻腔炎および鼻副鼻腔炎：治療 acute sinusitis and rhinosinusitis in adults treatment
English Journal
- Rising Opioid Prescribing in Adult U.S. Emergency Department Visits: 2001-2010.
- Mazer-Amirshahi M1, Mullins PM, Rasooly I, van den Anker J, Pines JM.Author information 1The Department of Emergency Medicine, The George Washington University, Washington, DC; The Department of Clinical Pharmacology, Children's National Medical Center, Washington, DC.AbstractOBJECTIVES: The objective was to describe trends in opioid and nonopioid analgesia prescribing for adults in U.S. emergency departments (EDs) over the past decade.
- Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.Acad Emerg Med.2014 Mar;21(3):236-243. doi: 10.1111/acem.12328.
- OBJECTIVES: The objective was to describe trends in opioid and nonopioid analgesia prescribing for adults in U.S. emergency departments (EDs) over the past decade.METHODS: Data from the National Hospital Ambulatory Medical Care Survey (NHAMCS) 2001 through 2010 were analyzed. ED visits for adult pat
- PMID 24628748
- Commonly prescribed medications in a population of hospice patients.
- Sera L1, McPherson ML, Holmes HM.Author information 11Department of Pharmacy Practice and Science, The University of Maryland School of Pharmacy, Baltimore, USA.AbstractAlthough much attention has been placed on appropriate symptom management at the end of life, little is known about the medications actually prescribed to people in hospice care. The purpose of this study was to determine the most commonly prescribed medications in a population of hospice patients. A retrospective review of a patient information database was conducted. The 6 most common drugs (acetaminophen, morphine, haloperidol, lorazepam, prochlorperazine, and atropine) were included in emergency kits provided to patients at admission. Opioid and nonopioid analgesics, anxiolytics, anticholinergics, and antipsychotics were the most commonly prescribed pharmacologic classes. This description of prescribing practices could be useful in creating more informed care plans, educating health care personnel, and anticipating the changing medication needs of patients as they enter hospice care.
- The American journal of hospice & palliative care.Am J Hosp Palliat Care.2014 Mar;31(2):126-31. doi: 10.1177/1049909113476132. Epub 2013 Feb 12.
- Although much attention has been placed on appropriate symptom management at the end of life, little is known about the medications actually prescribed to people in hospice care. The purpose of this study was to determine the most commonly prescribed medications in a population of hospice patients.
- PMID 23408370
- Analysis of the cytokine profile in the duodenal mucosa of refractory coeliac disease patients.
- Caruso R1, Marafini I, Sedda S, Del Vecchio Blanco G, Giuffrida P, MacDonald TT, Corazza GR, Pallone F, Di Sabatino A, Monteleone G.Author information 1*Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.AbstractRCD [refractory CD (coeliac disease)] is characterized by severe symptoms/signs of malabsorption and mucosal damage unresponsive to a GFD (gluten-free diet). The pathogenesis of RCD is not fully understood. In the present paper, we have characterized the mucosal profile of effector cytokines in RCD. Duodenal biopsies were taken from patients with RCD, patients with active CD and normal controls and were analysed for inflammatory cytokines by real-time PCR and ELISA. IFN (interferon)-γ and IL (interleukin)-21 transcripts were increased in active CD patients but not in RCD patients as compared with normal controls, whereas IL-17A RNA was up-regulated in both active CD and RCD. No significant increase in IL-15 transcripts was observed in both active CD and RCD, whereas IL-15 protein was increased in active CD. IL-6 and TNF (tumour necrosis factor)-α were up-regulated only in RCD. As a proof, we present the case of a woman affected by RCD who responded to anti-TNF-α treatment with improvement of malabsorptive symptoms/signs but no healing of mucosal lesions. The findings indicate that the profile of mucosal effector cytokines differs between RCD and active CD and suggest that TNF-α, IL-6 and IL-17A, but not Th1-type cytokines, could drive the detrimental response in this condition.
- Clinical science (London, England : 1979).Clin Sci (Lond).2014 Mar;126(6):451-8. doi: 10.1042/CS20130478.
- RCD [refractory CD (coeliac disease)] is characterized by severe symptoms/signs of malabsorption and mucosal damage unresponsive to a GFD (gluten-free diet). The pathogenesis of RCD is not fully understood. In the present paper, we have characterized the mucosal profile of effector cytokines in RCD.
- PMID 24125165
Japanese Journal
- がん疼痛治療における非オピオイド鎮痛薬長期投与の安全性に関する検討
- 海老沼 慶一,国分 秀也,佐々木 寿子 [他]
- 日本緩和医療薬学雑誌 4(2), 65-71, 2011-06
- NAID 40018938924
- Nonopioid and neuropathy-specific analgesic action of the nootropic drug nefiracetam in mice
- RASHID MH
- J Pharmacol Exp Ther 303, 226-231, 2003
- NAID 30003045084
Related Links
- a pain reliever (e.g., aspirin, ibuprofen) that is not derived from opium and does not have opium-like characteristics and effects.
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Related Pictures
★リンクテーブル★
| リンク元 | 「非麻薬性鎮痛薬」「非オピオイド性鎮痛薬」「non-narcotic analgesic」「非オピオイド鎮痛薬」 |
| 関連記事 | 「analgesic」 |
「非麻薬性鎮痛薬」
麻薬拮抗性鎮痛薬とオピオイド受容体
(標準麻酔科学 第2版p.182)
| 受容体 | μ | δ | κ | |
| 作用 | μ1 | μ2 | ||
| 上脊髄性鎮痛 | 幻覚・譫妄 | 脊髄性鎮痛 | ||
| 呼吸抑制 | 呼吸促進 | 呼吸抑制 | ||
| 身体依存性 | 不快感 | 鎮静 | ||
| 徐脈 | 頻脈 | 脈拍不変 | ||
| 縮瞳 | 散瞳 | 痙攣 | ||
| モルヒネ | agonist | - | agonist | |
| ペンタゾシン | antagonist | agonist | agonist | |
| ブプレノルフィン | partial agonist | - | agonist | |
| ブトルファノール | antagonist | - | agonist | |
| ナロキソン | antagonist | antagonist | antagonist | |
「非オピオイド性鎮痛薬」
「non-narcotic analgesic」
「非オピオイド鎮痛薬」
「analgesic」
- adj.
- 鎮痛性の
- n.