myopathy, encephalopathy, lactic acidosis and stroke-like episode

高乳酸血症と脳卒中様症状をもつ脳筋症

関

MELAS

WordNet

1. treat gingerly or carefully; "You have to stroke the boss"
2. a sudden loss of consciousness resulting when the rupture or occlusion of a blood vessel leads to oxygen lack in the brain (同)apoplexy, cerebrovascular_accident, CVA
3. (golf) the unit of scoring in golf is the act of hitting the ball with a club; "Nicklaus won by three strokes"
4. (sports) the act of swinging or striking at a ball with a club or racket or bat or cue or hand; "it took two strokes to get out of the bunker"; "a good shot requires good balance and tempo"; "he left me an almost impossible shot" (同)shot
5. a light touch with the hands (同)stroking
6. a single complete movement
7. any one of the repeated movements of the limbs and body used for locomotion in swimming or rowing
8. a light touch
9. a mark made on a surface by a pen, pencil, or paintbrush; "she applied the paint in careful strokes"
10. the oarsman nearest the stern of the shell who sets the pace for the rest of the crew
11. row at a particular rate
12. strike a ball with a smooth blow
13. touch lightly and repeatedly, as with brushing motions; "He stroked his long beard"
14. want to have; "Id like a beer now!"
15. a kind of person; "Well not see his like again"; "I cant tolerate people of his ilk" (同)ilk
16. a similar kind; "dogs, foxes, and the like", "we dont want the likes of you around here" (同)the like, the likes of
17. equal in amount or value; "like amounts"; "equivalent amounts"; "the same amount"; "gave one six blows and the other a like number"; "the same number" (同)same
18. resembling or similar; having the same or some of the same characteristics; often used in combination; "suits of like design"; "a limited circle of like minds"; "members of the cat family have like dispositions"; "as like as two peas in a pod"; "doglike devotion"; "a dreamlike quality" (同)similar
19. be fond of; "I like my nephews"
20. feel about or towards; consider, evaluate, or regard; "How did you like the Presidents speech last night?"
21. find enjoyable or agreeable; "I like jogging"; "She likes to read Russian novels"
22. a part of a broadcast serial (同)installment, instalment
23. a brief section of a literary or dramatic work that forms part of a connected series
24. a happening that is distinctive in a series of related events
25. abnormally high acidity (excess hydrogen-ion concentration) of the blood and other body tissues

PrepTutorEJDIC

1. (こぶし・武器・金づちなどの)『一打ち』,一撃,打告《+of+名》 / 《単数形で》(運の)巡り合わせ《+of+名》 / 《単数形で》(…の)ひと仕事,ひと働き;みごとな成果《+of+名》 / (鐘・時計などの)『打つ音』《+of+名》 / (時計などが打って示す)時刻 / (繰り返される動作・運動の)『一動作』,一行程 / (ペン・鉛筆・筆などの)ひと筆,ひとなで;筆の運び,筆致 / 卒中 / (ゴルフ・テニスなどの)一打ち,ストローク / (心臓などの)一打ち,鼓動,脈搏 / (ボートの)整調[手] / 〈ボート〉‘の'整調をこぐ / 《副詞[句]を伴って》〈ボール〉‘を'打つ
2. 〈髪・動物など〉‘を'なでる,さする / 〈人〉‘を'なだめる《+名+down, down+名》 / 一なで,一さすり
3. …‘を'『好む』,‘が'好きである / 《しばしば否定文で,またwould,《英》shouldと共に用いて》…‘を'望む,…したい / 『好む』;望む / 《複数形で》好み,好きな事
4. (外観・性質などが)…『に似た』,のような / (やり方,程度などが)…『と同じように』 / …『らしい』,にふさわいし / 《おもに話》たとえば…のような / 《名詞の前にのみ用いて》(性質・外観などが)同じの,(数量が)等しい / 《補語にのみ用いて》似ている,そっくりで / たぶん,おそらく(probably) / (…に)似た人(物),(…と)同等の人(物),匹敵する人(物)《+『of』+『名』》 / …のように / あたかも…のように
5. 《語・句・節を対等に結んで》…『と』…,…や…,および / 《数詞を結合して》…『足す』…,…に加えて / …『しかも』…,…して,同時に… / 《時間的に》『そして』,それから,すると(and then) / 《当然の帰結として》…『ので』,…だから(and so) / 《おもに話》《命令文などの後で》『そうすれば』,そうしたら / 《追加・強調して》それに,しかも / 《対照的な内容を導いて》ところが,しかし(but) / 《譲歩的に》それなのに,それでいながら / 《A and Bで一体の関係を表して》《単数扱い》 / 《同一語を反復して多数・継続などを表して》 / 《同一の複数名詞を結合して変化・種類などを表して》 / 《話》《「形容詞+and+形容詞」の形で前の形容詞が後に副詞的に働く》 / 《話》《「動詞come, goなど+and+動詞」の形でandとその後の動詞が不定詞の働きをして》 / 《「動詞+and+動詞」の形で後の動詞が現在分詞の意を表して》 / 《話》《文頭において前の質問・意見などに同意を示して》そうとも,そして(Yes!and) / 《話》《文頭に置いて驚き・疑念・非難などを表して》ほんとうに;…なのに
6. 挿話的なでき事(人生の特殊な経験など) / (小説・劇などの中の本筋と直接関係のない)挿話的な事件
7. 酸性症,酸中毒(血液中のアルカリ濃度が異常に低い状態)

English Journal

• Vasodilatation of multiple cerebral arteries in early stage of stroke-like episode with MELAS.

• Minobe S1, Matsuda A1, Mitsuhashi T1, Ishikawa M1, Nishimura Y1, Shibata K2, Ito E3, Goto Y4, Nakaoka T1, Sakura H1.
• Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.J Clin Neurosci.2015 Feb;22(2):407-8. doi: 10.1016/j.jocn.2014.05.021. Epub 2014 Aug 12.
• We describe a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), with multiple cerebral vasodilatations in a stroke-like episode visualised by using magnetic resonance angiography (MRA) and CT angiography (CTA). In the acute stroke-like episode st
• PMID 25128282

• [A case of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode/Leigh overlap syndrome].

• Matsui J, Takano T, Ryujin F, Anzai Y, Yoshioka S, Takeuchi Y, Goto Y.
• No to hattatsu. Brain and development.No To Hattatsu.2014 Sep;46(5):363-6.
• We experienced a case in which mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) was identified as complications following the onset of Leigh syndrome along with a 10191 T>C mutation of the mitochondrial gene. The case pertains to a 26-year-old woman. The di
• PMID 25403068

• Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) may respond to adjunctive ketogenic diet.

• Steriade C1, Andrade DM2, Faghfoury H3, Tarnopolsky MA4, Tai P2.
• Pediatric neurology.Pediatr Neurol.2014 May;50(5):498-502. doi: 10.1016/j.pediatrneurol.2014.01.009. Epub 2014 Jan 7.
• BACKGROUND: Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome can present management challenges. Refractory seizures and stroke-like episodes leading to disability are common.PATIENT: We analyzed the clinical, electrophysiologic, and radiologic data of a 22-
• PMID 24656211

Japanese Journal

• MERRF様の筋病理を呈したMELASの1例

• 臨床神経学 advpub(0), 2016
• NAID 130005132732

• Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS)/Leigh overlap症候群の1例

• 脳と発達 46(5), 363-366, 2014
• NAID 130005005728

• 脳卒中様発作急性期の頭痛発作に対してL-アルギニンが無効でミダゾラムが有効であったMELASの1例

• 臨床神経学 54(11), 882-887, 2014
• NAID 130004706045

Related Links

• Diffusion and Perfusion Characteristics of MELAS ...

INTRODUCTION MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and a stroke-like episode) is a mitochondrial disorder that is characterized by delayed growth, episodic vomiting, seizures, muscle ...

• Mitochondrial myopathy, encephalopathy, lactic acidosis, and ...

We report a case of Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes unmasked by use of Sodium Valproate in a 12-year-old boy who presented with headache and seizures. There was ...

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関連記事	「like」「episode」「stroke」「lactic」「acidosis」

「mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode syndrome」

　　[★]

ミトコンドリア脳筋症・乳酸アシドーシス・脳卒中様症候群、MELAS症候群

関

MELAS syndrome

「mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes」

　　[★] ミトコンドリア脳筋症・乳酸アシドーシス・脳卒中様発作症候群 MELAS

「like」

　　[★]

• v.

• 好む

• prep.

• 似ている、同様の

関

alike、as well as、care for、correspond、correspondingly、equally、favor、identically、likewise、prefer、resemble、same、similar、similarly、such

　 　 　 　 　 　 　 　 　 　

「episode」

　　[★]

• n.

• (再発性疾患の)症状の発現。
• 挿間期(病気の症状が現れる時期)。
• (慢性疾患の経過中に起こる一過性の増悪現象)エピソード

関

affect、event、onset、symptom onset

　 　 　 　

「stroke」

　　[★] 脳卒中 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　

「lactic」

　　[★]

• adj.

• 乳酸の

関

lactate、lactic acid

　 　

「acidosis」

　　[★] アシドーシス