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De Braekeleer M1,2,3, Douet-Guilbert N1,2,3, De Braekeleer E4.
Leukemia & lymphoma.Leuk Lymphoma.2017 Feb;58(2):257-265. Epub 2016 Jul 12.
The p15 gene (also known as CDKN2B, INK4B, p15INK4B), located in band 9p21, encodes a protein that induces a G1-phase cell cycle arrest through inhibition of CDK4/6 (cyclin-dependent kinase 4/6). It also plays an important role in the regulation of cellular commitment of hematopoietic progenitor cel
PMID 27401303

Functional interleukin-33 receptors are expressed in early progenitor stages of allergy-related granulocytes.

Tsuzuki H1, Arinobu Y1, Miyawaki K2, Takaki A1, Ota SI1, Ota Y1, Mitoma H1, Akahoshi M1, Mori Y1, Iwasaki H1, Niiro H2, Tsukamoto H1, Akashi K1.
Immunology.Immunology.2017 Jan;150(1):64-73. doi: 10.1111/imm.12667. Epub 2016 Sep 30.
Interleukin-33 (IL-33) induces T helper type 2 (Th2) cytokine production and eosinophilia independently of acquired immunity, leading to innate immunity-mediated allergic inflammation. Allergy-related innate myeloid cells such as eosinophils, basophils and mast cells express the IL-33 receptor (IL-3
PMID 27568595

Establishment and Characterization of Long-Term Cultures Derived from Primary Acute Myeloid Leukemia Cells for HDAC Inhibitor Research.

Romanski A1, Bug G2.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2017;1510:127-148.
Histone deacetylase (HDAC) inhibitors are promising drugs. These agents lead to growth inhibition, cell cycle arrest, premature senescence, and apoptosis of malignant cells. Aim of our studies was to determine the efficacy of HDAC inhibitors on the clinically most relevant population of human leukem
PMID 27761818