- 関
- MKP
WordNet
- aerate (sewage) so as to favor the growth of organisms that decompose organic matter (同)aerate
- make (substances) radioactive
- make active or more active; "activate an old file"
- make more adsorptive; "activate a metal"
- rendered active; e.g. rendered radioactive or luminescent or photosensitive or conductive
- (of e.g. a molecule) made reactive or more reactive (同)excited
- (military) set up and placed on active assignment; "a newly activated unit"
- (of sewage) treated with aeration and bacteria to aid decomposition
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- any of a group of enzymes that act as a catalyst in the hydrolysis of organic phosphates
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
PrepTutorEJDIC
- …'を'活動的にする / …‘に'放射能を与える / 〈物質〉'を'活性化する
- 蛋白(たんばく)質
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/16 02:59:37」(JST)
[Wiki en表示]
MAPK phosphatases are a class of phosphatases.
They are involved in MAP kinase signaling.[1]
References
- ^ MAPK Phosphatases at the US National Library of Medicine Medical Subject Headings (MeSH)
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Intracellular signaling peptides and proteins
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| MAP |
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| Calcium |
- Intracellular calcium-sensing proteins
- Calcineurin
- Ca2+/calmodulin-dependent protein kinase
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| G protein |
| Heterotrimeric |
| cAMP: |
- Heterotrimeric G protein
- Adenylate cyclase
- cAMP
- 3',5'-cyclic-AMP phosphodiesterase
- Protein kinase A
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| cGMP: |
- Guanylate cyclase
- cGMP
- 3',5'-cyclic-GMP phosphodiesterase
- Protein kinase G
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- G beta-gamma complex Gβ
- Gγ
- GNGT1
- GNGT2
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNG10
- GNG11
- GNG12
- GNG13
- BSCL2
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- G protein-coupled receptor kinase
- AMP-activated protein kinase
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|
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| Monomeric |
- ARFs
- Rabs
- Ras
- Rhos
- Arfs
- Ran
- Rhebs
- Raps
- RGKs
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|
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| Cyclin |
- Cyclin-dependent kinase inhibitor protein
- Cyclin-dependent kinase
- Cyclin
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| Lipid |
- Phosphoinositide phospholipase C
- Phospholipase C
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| Other protein kinase |
| Serine/threonine: |
- Casein kinase
- eIF-2 kinase
- Glycogen synthase kinase
- GSK1
- GSK2
- GSK-3
- GSK3A
- GSK3B
- IκB kinase
- Interleukin-1 receptor-associated kinase
- Lim kinase
- p21-activated kinases
- Rho-associated protein kinase
- Ribosomal s6 kinase
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| Tyrosine: |
- ZAP70
- Focal adhesion protein-tyrosine kinase
- BTK
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| both |
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| Other phosphoprotein phosphatase |
| Serine/threonine: |
|
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| Tyrosine: |
- protein tyrosine phosphatase: Receptor-like protein tyrosine phosphatase
- Sh2 domain-containing protein tyrosine phosphatase
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| both: |
- Dual-specificity phosphatase
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| Apoptosis |
- see apoptosis signaling pathway
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| GTP-binding protein regulators |
- see GTP-binding protein regulators
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| Other |
- Activating transcription factor 6
- Signal transducing adaptor protein
- I-kappa B protein
- Mucin-4
- Olfactory marker protein
- Phosphatidylethanolamine binding protein
- EDARADD
- PRKCSH
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see also deficiencies of intracellular signaling peptides and proteins
B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)
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MAP kinase activation
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| Initiation |
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| MAP kinase kinase kinase (MAP3K or MKKK) |
- MAP kinase kinase kinases
- MAP3K1
- MAP3K2
- MAP3K3
- MAP3K4
- MAP3K5
- MAP3K6
- MAP3K7
- MAP3K8
- RAFs
- RAF1
- ARAF
- BRAF
- KSR1
- KSR2)
- MLKs
- MAP3K12
- MAP3K13
- MAP3K9
- MAP3K10
- MAP3K11
- MAP3K7
- ZAK
- CDC7
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| MAP kinase kinase (MAP2K or MKK) |
- MAP2K1
- MAP2K2
- MAP2K3
- MAP2K4
- MAP2K5
- MAP2K6
- MAP2K7
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| MAP kinase |
- Extracellular signal-regulated kinases
- C-Jun N-terminal kinases
- P38 mitogen-activated protein kinases
- MAPK11
- MAPK12
- MAPK13
- MAPK14
- ERK5 kinase
- Atypical MAPKs
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| Phosphatase |
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B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)
|
|
UpToDate Contents
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English Journal
- SAMP8 mice have altered hippocampal gene expression in long term potentiation, phosphatidylinositol signaling, and endocytosis pathways.
- Armbrecht HJ, Siddiqui AM, Green M, Farr SA, Kumar VB, Banks WA, Patrick P, Shah GN, Morley JE.SourceGeriatric Research, Education and Clinical Center (GRECC), St Louis Veterans Affairs Medical Center, St Louis, MO, USA; Division of Geriatric Medicine, Saint Louis University School of Medicine, St Louis, MO, USA; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St Louis, MO, USA. Electronic address: hjarmbrec@aol.com.
- Neurobiology of aging.Neurobiol Aging.2014 Jan;35(1):159-168. doi: 10.1016/j.neurobiolaging.2013.07.018. Epub 2013 Aug 19.
- The senescence-accelerated mouse (SAMP8) strain exhibits decreased learning and memory and increased amyloid beta (Aβ) peptide accumulation at 12 months. To detect differences in gene expression in SAMP8 mice, we used a control mouse that was a 50% cross between SAMP8 and CD-1 mice and which showe
- PMID 23969180
- miR-222 and miR-29a contribute to the drug-resistance of breast cancer cells.
- Zhong S, Li W, Chen Z, Xu J, Zhao J.SourceCenter of Clinical Laboratory Science, Jiangsu Cancer Hospital Affiliated to Nanjing Medical University, Nanjing 210009, China.
- Gene.Gene.2013 Nov 15;531(1):8-14. doi: 10.1016/j.gene.2013.08.062. Epub 2013 Aug 29.
- Adriamycin (Adr) and docetaxel (Doc) are two chemotherapeutic agents commonly used in the treatment of breast cancer. However, patients with breast cancer who are treated by the drugs often develop resistance to them and some other drugs. Recently studies have shown that microRNAs (miRNAs, miRs) pla
- PMID 23994196
- Molecular mechanisms of glucocorticoid action in mast cells.
- Oppong E, Flink N, Cato AC.SourceKarlsruhe Institute of Technology, Institute of Toxicology and Genetics, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany. Electronic address: emmanuel.oppong@kit.edu.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2013 Nov 5;380(1-2):119-26. doi: 10.1016/j.mce.2013.05.014. Epub 2013 May 22.
- Glucocorticoids are compounds that have successfully been used over the years in the treatment of inflammatory disorders. They are known to exhibit their effects through the glucocorticoid receptor (GR) that acts to downregulate the action of proinflammatory transcription factors such as AP-1 and NF
- PMID 23707629
Japanese Journal
- Ursolic Acid Induces Apoptosis Through Mitochondrial Intrinsic Pathway and Suppression of ERK1/2 MAPK in HeLa Cells
- Li Yanhong,Lu Xueying,Qi Hongxue [他]
- Journal of pharmacological sciences 125(2), 202-210, 2014-06
- NAID 40020097701
- Ursolic Acid Induces Apoptosis Through Mitochondrial Intrinsic Pathway and Suppression of ERK1/2 MAPK in HeLa Cells
- Li Yanhong,Lu Xueying,Qi Hongxue,Li Xiaobo,Xiao Xiangwen,Gao Jianfeng
- Journal of Pharmacological Sciences 125(2), 202-210, 2014
- Ursolic acid (UA), a natural pentacyclic triterpenoid compound, has been demonstrated to induce apoptosis in various tumors. The aim of the present study was to elucidate the molecular mechanisms of U …
- NAID 130004438631
- Osteoblastic differentiation of stromal ST-2 cells from octacalcium phosphate exposure via p38 signaling pathway
- NISHIKAWA Ryuhei,ANADA Takahisa,ISHIKO-UZUKA Risa,SUZUKI Osamu
- Dental Materials Journal, 2014
- … The present study investigated the role of mitogen-activated protein kinase (MAPK) signaling in osteoblastic differentiation of stromal ST-2 cells induced by synthetic octacalcium phosphate (OCP) incubation. … OCP increased alkaline phosphatase (ALP) activity and the mRNA expression of differentiation markers via the p38 signaling pathway. …
- NAID 130003394964
Related Links
- Mitogen-activated protein kinases (MAPKs) are key regulators of cellular physiology and immune responses, and abnormalities in MAPKs are implicated in many dise ... Fig. 1. MKP-1 restrains pro-inflammatory cytokine ...
- c-Jun N-terminal kinase (JNK) activation promotes hepatocyte death during acetaminophen overdose, a common cause of drug-induced liver failure. While mitogen-activated protein kinase (MAPK) phosphatase (Mkp)-1 is a critical ...
★リンクテーブル★
[★]
- 英
- mitogen-activated protein kinase phosphatase、MKP
- 関
- マイトジェン活性化プロテインキナーゼホスファターゼ、MAPキナーゼ脱リン酸化酵素
[★]
- 英
- mitogen-activated protein kinase phosphatase
- 関
- マイトジェン活性化プロテインキナーゼホスファターゼ、MAPキナーゼホスファターゼ
[★]
- 英
- mitogen-activated protein kinase phosphatase
- 関
- MAPキナーゼホスファターゼ、MAPキナーゼ脱リン酸化酵素
[★]
- 関
- mitogen-activated protein kinase phosphatase
[★]
ホスファターゼ、フォスファターゼ、脱リン酸化酵素、脱リン酸酵素
- 関
- phosphohydrolase、phosphoric monoester hydrolase
[★]
- 関
- activate、activated form、activation、turn on
[★]
- 関
- activated、activation、turn on
[★]
キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase
[★]
プロテインキナーゼ
- 同
- protein kinases