WordNet

aerate (sewage) so as to favor the growth of organisms that decompose organic matter (同)aerate
make (substances) radioactive
make active or more active; "activate an old file"
make more adsorptive; "activate a metal"
rendered active; e.g. rendered radioactive or luminescent or photosensitive or conductive
(of e.g. a molecule) made reactive or more reactive (同)excited
(military) set up and placed on active assignment; "a newly activated unit"
(of sewage) treated with aeration and bacteria to aid decomposition
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
an agent that triggers mitosis

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1. 転移性乳癌における予後および予測因子 prognostic and predictive factors in metastatic breast cancer
2. リウマチ性疾患におけるサイトカインネットワーク：治療の意味 cytokine networks in rheumatic diseases implications for therapy
3. 前立腺癌の分子生物学 molecular biology of prostate cancer
4. レフルノミドによる関節リウマチの治療 leflunomide in the treatment of rheumatoid arthritis
5. 炭疽菌の微生物学、病因、および疫学 microbiology pathogenesis and epidemiology of anthrax

Ghrelin prevents cardiac cell apoptosis during cardiac remodelling post experimentally induced myocardial infarction in rats via activation of Raf-MEK1/2-ERK1/2 signalling.

Eid RA, Alkhateeb MA, Al-Shraim M, Eleawa SM, Shatoor AS, El-Kott AF, Zaki MSA, Shatoor KA, Bin-Jaliah I, Al-Hashem FH.
Archives of physiology and biochemistry. 2019 May;125(2)93-103.
Mechanisms by which ghrelin affords its cardioprotection in mammals remained unclear. To examine if ghrelin confers cardio-protection during cardiac remodelling post-MI by modulating the RAF-1-MEK1/2-ERK1/2 signalling pathway. Rats were divided into control, sham, sham + ghrelin, myocardial infa
PMID 29447000

Metformin increases antitumor activity of MEK inhibitor binimetinib in 2D and 3D models of human metastatic melanoma cells.

Ryabaya O, Prokofieva A, Akasov R, Khochenkov D, Emelyanova M, Burov S, Markvicheva E, Inshakov A, Stepanova E.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019 Jan;109()2548-2560.
Melanoma is one of the most aggressive and treatment-resistant tumors that responsible for majority of skin-cancer related deaths. Here we propose a combination of MEK inhibitor binimetinib with metformin as a promising therapy against human melanoma cells in vitro, including BRAF -mutated A375, Mel
PMID 30551515

Characterization and functional analysis of grouper (Epinephelus coioides) MEK1 and MEK2.

Mo ZQ, Han R, Wang JL, Ni LY, Su YL, Lai XL, He ZC, Chen HP, Li YW, Sun HY, Luo XC, Dan XM.
Fish & shellfish immunology. 2019 Jan;84()1090-1097.
MEK dual-specificity protein kinases are a group of mitogen-activated protein kinase kinases, which act as an integration point by transferring extracellular signals to the nucleus. To investigate the function of MEK in teleost fish, we cloned MEK1 and MEK2 cDNA sequences from the orange-spotted gro
PMID 30419398

The Role of Big Mitogen-Activated Protein Kinase 1 (BMK1)/Extracellular Signal-Regulated Kinase 5 (ERK5) in the Pathogenesis and Progression of Atherosclerosis

Hepatitis B virus surface antigen can activate human monocyte-derived dendritic cells by nuclear factor kappa B and p38 mitogen-activated protein kinase mediated signaling

岡田眞里子
応用数理 22(3), 193-201, 2012-09-26
… For example, transient and sustained mitogen-activated protein kinase (MAPK) induce proliferation and differentiation of MCF-7 breast cancer cells, respectively. …
NAID 110009518432

リンク元	「MAP kinase kinase 2」「マイトジェン活性化プロテインキナーゼキナーゼ2」
関連記事	「activated」「activate」「kinase」「protein kinase」