WordNet

a form of carcinoma of the mesothelium lining lungs or abdomen or heart; usually associated with exposure to asbestos dust
an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Cancer risks in children with congenital malformations in the nervous and circulatory system-A population based cohort study.

Sun Y1, Overvad K2, Olsen J3.
Cancer epidemiology.Cancer Epidemiol.2014 May 3. pii: S1877-7821(14)00069-1. doi: 10.1016/j.canep.2014.04.001. [Epub ahead of print]
AIM: We estimated the age and organ-specific cancer risk for children with a congenital malformation (CM) in the nervous or in the circulatory system.METHODS: We identified 1,709,456 live born singletons in Denmark between 1 January 1977 and 31 December 2007 and excluded children with chromosomal bi
PMID 24802852

p16 FISH Deletion in Surface Epithelial Mesothelial Proliferations Is Predictive of Underlying Invasive Mesothelioma.

Hwang H1, Tse C, Rodriguez S, Gown A, Churg A.
The American journal of surgical pathology.Am J Surg Pathol.2014 May;38(5):681-8. doi: 10.1097/PAS.0000000000000176.
An atypical mesothelial proliferation along the pleural or peritoneal surface without evidence of invasive tumor poses a diagnostic challenge. Homozygous deletion of p16 (CDKN2A) by fluorescence in situ hybridization (FISH) has been shown to be a good marker of malignancy in mesothelial proliferatio
PMID 24503757

Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.

Li A1, Morton JP1, Ma Y1, Karim SA1, Zhou Y1, Faller WJ1, Woodham EF1, Morris HT1, Stevenson RP1, Juin A1, Jamieson NB2, Mackay CJ2, Carter CR2, Leung HY1, Yamashiro S3, Blyth K1, Sansom OJ1, Machesky LM4.
Gastroenterology.Gastroenterology.2014 May;146(5):1386-1396.e17. doi: 10.1053/j.gastro.2014.01.046. Epub 2014 Jan 23.
BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is often lethal because it is highly invasive and metastasizes rapidly. The actin-bundling protein fascin has been identified as a biomarker of invasive and advanced PDAC and regulates cell migration and invasion in vitro. We investigat
PMID 24462734