メサンギウム細胞
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/09 01:52:38」(JST)
[Wiki en表示]
Mesangial cells are specialized cells around blood vessels in the kidneys, at the mesangium. They are specialized smooth muscle cells that function to regulate blood flow through the capillaries, usually divided into two types, each having a very distinct function and location:
- Extraglomerular mesangial cells
- Intraglomerular mesangial cells
Cells in humans derived from mesoderm
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Paraxial |
Cartilage/bone/
muscle
(MSC) |
OCP |
bone: |
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cartilage: |
- Chondroblast → Chondrocyte
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Myofibroblast |
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muscle: |
- Myoblast → Myocyte
- Myosatellite cell
- Tendon cell
- Cardiac muscle cell
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adipose: |
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Digestive system |
- Interstitial cell of Cajal
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Intermediate |
Urinary system (RSC) |
- Angioblast → Endothelial cell
- Mesangial cell
- Intraglomerular
- Extraglomerular
- Juxtaglomerular cell
- Macula densa cell
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- Stromal cell → Interstitial cell → Telocytes
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- Simple epithelial cell → Podocyte
- Kidney proximal tubule brush border cell
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Reproductive system |
- Sertoli cell
- Leydig cell
- Granulosa cell
- Peg cell
- germ cells
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Lateral plate/
hemangioblast |
Blood/immune
(HSC) |
Lymphoid (CFU-L) |
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Myeloid (CFU-GEMM) |
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Circulatory system |
- Endothelial progenitor cell
- Endothelial colony forming cell
- Endothelial stem cell
- Angioblast/Mesoangioblast
- Pericyte
- Mural cell
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Index of developmental medicine
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Description |
- Embryology
- Cell lines
- endoderm
- mesoderm
- ectoderm
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Disease |
- Due to toxins
- Syndromes
- Chromosomal
- Neonate
- Twins
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UpToDate Contents
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- 1. 糸球体の免疫障害の機序 mechanisms of immune injury of the glomerulus
- 2. IgA腎症の病因 pathogenesis of iga nephropathy
- 3. IgA腎症の臨床症状および診断 clinical presentation and diagnosis of iga nephropathy
- 4. 膜性増殖性糸球体腎炎の臨床像、分類、および原因 clinical presentation classification and causes of membranoproliferative glomerulonephritis
- 5. 小児における糸球体腎炎の病因と原因の概要 overview of the pathogenesis and causes of glomerulonephritis in children
English Journal
- Pentamethylquercetin ameliorates fibrosis in diabetic Goto-Kakizaki rat kidneys and mesangial cells with suppression of TGF-β/Smads signaling.
- Xin X, Li XH, Wu JZ, Chen KH, Liu Y, Nie CJ, Hu Y, Jin MW.SourceDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan 430030, China.
- European journal of pharmacology.Eur J Pharmacol.2013 Aug 5;713(1-3):6-15. doi: 10.1016/j.ejphar.2013.04.045. Epub 2013 May 9.
- Pentamethylquercetin (PMQ) has been shown to possess glucose-lowering properties, but its effect on renal fibrosis in diabetes is still unclear. This study was designed to investigate the effect of PMQ on renal fibrosis and the underlying mechanisms in spontaneous type II diabetic Goto-Kakizaki rats
- PMID 23665496
- FOG2 Protein Down-regulation by Transforming Growth Factor-β1-induced MicroRNA-200b/c Leads to Akt Kinase Activation and Glomerular Mesangial Hypertrophy Related to Diabetic Nephropathy.
- Park JT, Kato M, Yuan H, Castro N, Lanting L, Wang M, Natarajan R.SourceFrom the Division of Molecular Diabetes Research, Department of Diabetes, Beckman Research Institute of City of Hope, Duarte, California 91010.
- The Journal of biological chemistry.J Biol Chem.2013 Aug 2;288(31):22469-80. doi: 10.1074/jbc.M113.453043. Epub 2013 Jun 20.
- Glomerular hypertrophy is a hallmark of diabetic nephropathy. Akt kinase activated by transforming growth factor-β1 (TGF-β) plays an important role in glomerular mesangial hypertrophy. However, the mechanisms of Akt activation by TGF-β are not fully understood. Recently, miR-200 and its target FO
- PMID 23788640
- α1β1 Integrin/Rac1-Dependent Mesangial Invasion of Glomerular Capillaries in Alport Syndrome.
- Zallocchi M, Johnson BM, Meehan DT, Delimont D, Cosgrove D.SourceBoys Town National Research Hospital, Omaha, Nebraska.
- The American journal of pathology.Am J Pathol.2013 Aug 1. pii: S0002-9440(13)00471-9. doi: 10.1016/j.ajpath.2013.06.015. [Epub ahead of print]
- Alport syndrome, hereditary glomerulonephritis with hearing loss, results from mutations in type IV collagen COL4A3, COL4A4, or COL4A5 genes. The mechanism for delayed glomerular disease onset is unknown. Comparative analysis of Alport mice and CD151 knockout mice revealed progressive accumulation o
- PMID 23911822
Japanese Journal
- 3) 血管内皮から観た妊娠高血圧症候群の病態とその発症予知(シンポジウム2:周産期「妊娠高血圧症候群の基礎と臨床-予防・治療の新戦略に向けて」,第65回日本産科婦人科学会・学術講演会)
- 松原 圭一
- 日本産科婦人科學會雜誌 65(11), 2591-2603, 2013-11-01
- … The profile of helper T cell was changed to Th1 dominancy in the mice. … Renal vascular lumen was narrowed by increased mesangial matrix in the glomeruli. … Chloride conductance regulatory protein (pICln) DNA or siRNA was transfected into trophoblast cell line (TBT) or EPC cell line (BME) by lipofectamine method. …
- NAID 110009674983
- 3) 血管内皮から観た妊娠高血圧症候群の病態とその発症予知(シンポジウム2:周産期「妊娠高血圧症候群の基礎と臨床-予防・治療の新戦略に向けて」,第65回日本産科婦人科学会・学術講演会)
- 松原 圭一
- 日本産科婦人科學會雜誌 65(11), 2591-2603, 2013-11-01
- … The profile of helper T cell was changed to Th1 dominancy in the mice. … Renal vascular lumen was narrowed by increased mesangial matrix in the glomeruli. … Chloride conductance regulatory protein (pICln) DNA or siRNA was transfected into trophoblast cell line (TBT) or EPC cell line (BME) by lipofectamine method. …
- NAID 110009661871
- Glomerular Endotheliosis in a Pregnant Woman with Severe Gestational Proteinuria
- Koizumi Mitsuteru,Yahata Kensei,Ohno Shoko,Koga Kenichi,Kikuchi Yuko,Hasegawa Chinatsu,Seta Koichi,Kuwahara Takashi,Sugawara Akira
- Internal Medicine 52(17), 1943-1947, 2013
- … Electron microscopy revealed an expansion of the subendothelial zone as well as mesangial cell interposition. …
- NAID 130003365803
Related Links
- Abstract Mesangial cells and their matrix form the central stalk of the glomerulus and are part of a functional unit interacting closely with endothelial cells and podocytes. Alterations in one cell type can produce changes ...
- mes·an·gi·al cell a phagocytic cell in the capillary tuft of the renal glomerulus, interposed between endothelial cells and the basement membrane in the central or stalk region of the tuft. Synonym(s): deep cell, intercapillary cell
Related Pictures
★リンクテーブル★
[★]
- 英
- mesangial cell (HIS,Z)
- 同
- 血管間膜細胞
- 関
- 糸球体
概念
- ボウマン嚢の中では輸入細動脈はメサンギウム細胞という特殊な結合組織性の細胞によって支持される (HIS.373)
種類
- 糸球体外メサンギウム細胞
- 糸球体内メサンギウム細胞
- 腎小体・血管極に存在する
- 食作用を持ち、基底板の吸収に関与 (HIS.373)
臨床関連
- メサンギウム細胞の増殖:先行感染・疾患で産生された抗原により形成された免疫複合体のメサンギウム領域への沈着により炎症が起きた結果生じるとされる → 急性糸球体腎炎、IgA腎症、ヘノッホ・シェンーライン紫斑病、膜性増殖性糸球体腎炎]]
[★]
- 英
- mesangial cell
- 関
- メサンギウム細胞
[★]
- 関
- kidney mesangial cell、mesangial cell、renal mesangial cell
[★]
- 関
- glomerular mesangial cell、kidney mesangial cell、mesangial cell
[★]
- 関
- glomerular mesangial cell、mesangial cell、renal mesangial cell
[★]
- 関
- glomerular mesangium、mesangium
[★]
細胞