ピリドキサール5-リン酸グルタミン酸マグネシウム
WordNet
- a salt of phosphoric acid (同)orthophosphate, inorganic_phosphate
- carbonated drink with fruit syrup and a little phosphoric acid
- a light silver-white ductile bivalent metallic element; in pure form it burns with brilliant white flame; occurs naturally only in combination (as in magnesite and dolomite and carnallite and spinel and olivine) (同)Mg, atomic number 12
- a salt or ester of glutamic acid
PrepTutorEJDIC
- 〈U〉リン酸塩 / 《複数形で》リン酸肥料
- マグネシウム(金属元素;化学記号は『Mg』)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/12/12 01:13:40」(JST)
[Wiki en表示]
Magnesium pyridoxal 5-phosphate glutamate
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Systematic (IUPAC) name |
(2S)-2,5-diamino-5-oxopentanoic acid;
(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate |
Clinical data |
Trade names |
Sedalipid |
Pregnancy cat. |
? |
Legal status |
? |
Identifiers |
CAS number |
62055-05-4 (magnesium salt) |
ATC code |
C10AX07 |
PubChem |
CID 173846 |
ChemSpider |
151728 Y |
Chemical data |
Formula |
C13H20N3O9P |
Mol. mass |
393.286 g/mol |
SMILES
- O=C(N)CC[C@H](N)C(=O)O.O=P(O)(O)OCc1cnc(c(O)c1C=O)C
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InChI
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InChI=1S/C8H10NO6P.C5H10N2O3/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14;6-3(5(9)10)1-2-4(7)8/h2-3,11H,4H2,1H3,(H2,12,13,14);3H,1-2,6H2,(H2,7,8)(H,9,10)/t;3-/m.0/s1 Y
Key:BCARVEADLDZBJT-HVDRVSQOSA-N Y
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Y (what is this?) (verify)
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Magnesium pyridoxal 5-phosphate glutamate (trade name Sedalipid) is a hypolipidemic agent.[1]
References[edit]
- ^ Schuitemaker GE, van der Pol GA, Aretz CP, Dinant GJ (2001). "A placebo-controlled, double-blind, randomised trial of magnesium-pyridoxal-5'-phosphate-glutamate for hypercholesterolaemia and other clinical-chemical risk factors of cardiovascular disease in a primary care setting". Eur. J. Clin. Pharmacol. 56 (12): 857–63. doi:10.1007/s002280000247. PMID 11317472.
Lipid modifying agents (C10)
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GI tract |
Cholesterol absorption inhibitors, NPC1L1
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Bile acid sequestrants/resins (LDL)
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- Cholestyramine
- Colestipol
- Colestilan
- Colextran
- Colesevelam
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Liver |
Statins (HMG-CoA reductase, LDL)
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- Simvastatin#
- Atorvastatin
- Fluvastatin
- Lovastatin
- Mevastatin
- Pitavastatin
- Pravastatin
- Rosuvastatin
- Cerivastatin‡
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Niacin and derivatives (HDL and LDL)
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- Niceritrol
- Niacin
- Nicofuranose
- Aluminium nicotinate
- Nicotinyl alcohol
- Acipimox
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MTTP inhibitors (VLDL)
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- Dirlotapide
- Lomitapide
- Mitratapide
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Blood vessels |
Fibrates (PPAR)
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- Clofibrate‡
- Bezafibrate
- Aluminium clofibrate
- Gemfibrozil
- Fenofibrate
- Simfibrate
- Ronifibrate
- Ciprofibrate
- Etofibrate
- Clofibride
- Clinofibrate
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CETP inhibitors (HDL)
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- Anacetrapib†
- Dalcetrapib§
- Evacetrapib§
- Torcetrapib†
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Combinations |
- Niacin/lovastatin
- Niacin/simvastatin
- Ezetimibe/simvastatin
- Ezetimibe/atorvastatin
- Niacin/laropiprant
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Other |
- Dextrothyroxine‡
- Probucol
- Tiadenol
- Benfluorex
- Meglutol
- Omega-3-triglycerides
- Magnesium pyridoxal 5-phosphate glutamate
- Policosanol
- Lapaquistat§
- Mipomersen
- Alipogene tiparvovec
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m
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k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon
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m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)
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UpToDate Contents
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English Journal
- The impact of dietary changes and dietary supplements on lipid profile.
- Huang J, Frohlich J, Ignaszewski AP.SourceHealthy Heart Program, St. Paul's Hospital-Burrard Building 180-1081, Vancouver, British Columbia, Canada.
- The Canadian journal of cardiology.Can J Cardiol.2011 Jul-Aug;27(4):488-505.
- With a growing number of dietary interventions that claim to improve lipid profile, it is important to ensure that these claims are evidence based. The objective of this study was to make recommendations for dietary regimens by analyzing their effectiveness and the level of evidence. We searched MED
- PMID 21801978
- D-amino acids in the brain: the biochemistry of brain serine racemase.
- Baumgart F, Rodríguez-Crespo I.SourceDepartamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Spain.
- The FEBS journal.FEBS J.2008 Jul;275(14):3538-45.
- It has been recently established that in various brain regions D-serine, the product of serine racemase, occupies the so-called 'glycine site' within N-methyl D-aspartate receptors. Mammalian brain serine racemase is a pyridoxal-5' phosphate-containing enzyme that catalyzes the racemization of L-ser
- PMID 18564178
Related Links
- Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3] For patient information, click here Magnesium pyridoxal 5-phosphate glutamate (trade name Sedalipid) is a hypolipidemic agent. [1] References ↑ {{#if:Schuitemaker GE, van der Pol ...
- References for "Magnesium pyridoxal 5-phosphate glutamate" im Internet, an Universitäten und in der Literatur... cyclopaedia.net ... Biotics Research - B6 Phosphate 100T Andrea Rosanoff, 2003 Source of B6 Phosphate. Coenzyme ...
Related Pictures
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcQDnNoTezS6hLjkVISH7WkcptXP3Uw6D2tC3DTnzGtPqTwHjxfTWWdccYFc:http://upload.wikimedia.org/wikipedia/commons/b/bc/Magnesium_pyridoxal_5-phosphate_glutamate.png)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcRUovBvY9CkijrD5IXonvSR-xpHktPiK-O-SwU3I3AIrC210YADZ0C77g:http://upload.wikimedia.org/wikipedia/commons/thumb/b/bc/Magnesium_pyridoxal_5-phosphate_glutamate.png/220px-Magnesium_pyridoxal_5-phosphate_glutamate.png)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcTHCHpXEEmxh9a7AnF90LxlIOoaka0Ax3iyE6wInxvi5edDF_I7ljRSNpXe:http://patentimages.storage.googleapis.com/EP0861258B1/00040001.png)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcRJM2FHTLYxfF2FECESYLqZTjkMF0PRCYgA43NC62fHT9fjsPxOEVZwdg:http://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi%3Ft%3Dl%26cid%3D173846)
![](http://msp.c.yimg.jp/image?q=tbn:ANd9GcRWE-hEgpaoGGQkqxkfrY14jEK-t5MwCWImpxbzXFSGrToVF7N2MU7lzQ:http://upload.wikimedia.org/wikipedia/commons/thumb/b/bc/Magnesium_pyridoxal_5-phosphate_glutamate.png/150px-Magnesium_pyridoxal_5-phosphate_glutamate.png)
★リンクテーブル★
[★]
- 英
- magnesium pyridoxal 5-phosphate glutamate
[★]
- 関
- inorganic phosphate、orthophosphate、orthophosphoric acid、phospho、phosphoester、phosphoric、phosphoric acid、phosphoric acid ester、phosphorus
[★]
グルタミン酸、グルタメート、グルタメイト、(化合物)グルタミン酸塩
[★]
マグネシウム、Mg+