リンパ球抗原受容体
WordNet
- any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection (同)lymph cell
PrepTutorEJDIC
- 抗原(生物の体内にはいって免疫体を作る物質)
- =sense organ / 受信装置
UpToDate Contents
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English Journal
- Immunotherapeutic Agents in Non-small-cell Lung Cancer Finally Coming to the Front Lines.
- Ruiz R1, Hunis B, Raez LE.
- Current oncology reports.Curr Oncol Rep.2014 Sep;16(9):400. doi: 10.1007/s11912-014-0400-6.
- Non-small-cell lung cancer usually carries a dismal prognosis. Novel treatment approaches are clearly warranted. Immunotherapy has emerged as a promising area of research developing agents that manipulate the immune system to induce antitumor responses while avoiding major toxicity. New vaccines and
- PMID 25030654
- Composition of Innate Lymphoid Cell Subsets in the Human Skin: Enrichment of NCR(+) ILC3 in Lesional Skin and Blood of Psoriasis Patients.
- Teunissen MB1, Munneke JM2, Bernink JH3, Spuls PI1, Res PC1, Te Velde A3, Cheuk S4, Brouwer MW1, Menting SP1, Eidsmo L4, Spits H5, Hazenberg MD2, Mjösberg J6.
- The Journal of investigative dermatology.J Invest Dermatol.2014 Sep;134(9):2351-60. doi: 10.1038/jid.2014.146. Epub 2014 Mar 21.
- Innate lymphoid cells (ILCs) are increasingly appreciated as important regulators of tissue homeostasis and inflammation. However, their role in human skin remains obscure. We found that healthy peripheral blood CD117(+) ILC3, lacking the natural cytotoxicity receptor (NCR) NKp44 (NCR(-) ILC3), CD11
- PMID 24658504
- Transcriptional and Posttranscriptional Regulation of Cytokine Gene Expression in HIV-1 Antigen-Specific CD8+ T Cells That Mediate Virus Inhibition.
- Payne TL1, Blackinton J2, Frisbee A3, Pickeral J4, Sawant S3, Vandergrift NA3, Freel SA5, Ferrari G5, Keene JD2, Tomaras GD6.
- Journal of virology.J Virol.2014 Sep 1;88(17):9514-28. doi: 10.1128/JVI.00802-14. Epub 2014 Jun 4.
- The ability of CD8(+) T cells to effectively limit HIV-1 replication and block HIV-1 acquisition is determined by the capacity to rapidly respond to HIV-1 antigens. Understanding both the functional properties and regulation of an effective CD8(+) response would enable better evaluation of T cell-di
- PMID 24899193
Japanese Journal
- WT1ペプチドワクチン施行したCML患者における抗原特異的細胞障害性T細胞のT細胞受容体β鎖可変領域レパトワの解析
- Mucosal-Associated Invariant T Cell Is a Potential Marker to Distinguish Fibromyalgia Syndrome from Arthritis
Related Links
- T-cell re·cep·tor (TCR) (sel rĕ-sep'tŏr) An adhesion molecule on the membrane of T lymphocytes, which serves as the receptor for antigen bound to antigen-presenting cells (APC) through MHC molecules. It is expressed in a complex ...
- It is easy to imagine at least three possible ways in which cohesin might contribute to the regulation of lymphocyte receptor loci and the control of V(D)J recombination. The first and perhaps most obvious possibility is that cohesin ...
Related Pictures
★リンクテーブル★
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- 英
- lymphocyte antigen receptor
- 関
- BCR、TCR、B細胞、T細胞
BCRとTCRの成立過程における差異
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BCR
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TCR
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v-region assembly
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somatic reombination of DNA
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有り
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有り
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junctional diversity
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imprecise joining, N-sequence insertion in DNA
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有り
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有り
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transcriptional activation
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activation of promoter by proximity to the enhancer
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有り
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有り
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switch recombination
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somatic recombination of DNA
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有り
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無し
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somatic hypermutation
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DNA point mutation
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有り
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無し
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IgM, IgD expression on surface
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differential splicing of DNA
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有り
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無し
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membrane vs secreted form
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differential splicing of RNA
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有り
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無し
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リンパ球
- 同
- lymphocytes&development
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