WordNet

unrefined in character; "low comedy"
an air mass of lower pressure; often brings precipitation; "a low moved in over night bringing sleet and snow" (同)depression
a low level or position or degree; "the stock market fell to a new low"
used of sounds and voices; low in pitch or frequency (同)low-pitched
very low in volume; "a low murmur"; "the low-toned murmur of the surf" (同)low-toned
in a low position; near the ground; "the branches hung low"
less than normal in degree or intensity or amount; "low prices"; "the reservoir is low"
literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow"
a dish made by folding a piece of pastry over a filling
British political cartoonist (born in New Zealand) who created the character Colonel Blimp (1891-1963) (同)David Low, Sir David Low, Sir David Alexander Cecil Low
abnormal loss of bony tissue resulting in fragile porous bones attributable to a lack of calcium; most common in postmenopausal women

PrepTutorEJDIC

(高さ・位置が)『低い』,低い所にある / (価格・数量・程度などが)『低い』,少ない / (身分・地位などが)『低い』,卑しい / (人格・行為などが)『卑しい』,下劣な,下品な / 《補語にのみ用いて》(体が)『弱った』;元気のない,憂うつな / (供給が)不十分な;(…が)乏しい《+『in』(『on』)+『名』》 / (音・声が)低い,小さい / (生物が)下等な / 『低く』,低い所に / (価格・程度などが)『安く』,低く / 低い声(調子)で;静かに / 最低点,最低水準
(牛の)モーという鳴き声 / (牛が)モーと鳴く
〈C〉(車などの)転覆,転倒 / 〈U〉《しばしば a…》(一定期間内の)総取り引き高,売り上げ高 / 〈U〉《しばしば s…》(一定期間内の)補充労働者の総数(割合) / 〈U〉《しばしば a…》(一定期間内の)商品の回転率 / 〈C〉〈U〉(半円形形または三角形の)折り重ねパイ
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1. 実質臓器移植または幹細胞移植後の骨粗鬆症 osteoporosis after solid organ or stem cell transplantation
2. 閉経前の骨粗鬆症の疫学および病因 epidemiology and etiology of premenopausal osteoporosis
3. 男性における骨粗鬆症の治療 treatment of osteoporosis in men
4. 閉経後の女性における骨粗鬆症の臨床症状、診断、および評価 clinical manifestations diagnosis and evaluation of osteoporosis in postmenopausal women
5. 慢性腎臓病患者における骨粗鬆症：診断、評価およびマネージメント osteoporosis in patients with chronic kidney disease diagnosis evaluation and management

Teriparatide and bone turnover and formation in a hemodialysis patient with low-turnover bone disease: a case report.

Palcu P1, Dion N2, Ste-Marie LG2, Goltzman D3, Radziunas I1, Miller PD4, Jamal SA5.
American journal of kidney diseases : the official journal of the National Kidney Foundation.Am J Kidney Dis.2015 Jun;65(6):933-6. doi: 10.1053/j.ajkd.2015.01.025. Epub 2015 Apr 2.
Teriparatide, a recombinant form of parathyroid hormone, is an anabolic agent approved for use in women and men with osteoporosis. However, it is not well studied in people with chronic kidney disease (CKD). We report on a patient with stage 5 CKD treated with dialysis who presented to our clinic wi
PMID 25843705

A single nucleotide polymorphism in osteonectin 3' untranslated region regulates bone volume and is targeted by miR-433.

Dole NS1, Kapinas K, Kessler CB, Yee SP, Adams DJ, Pereira RC, Delany AM.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.J Bone Miner Res.2015 Apr;30(4):723-32. doi: 10.1002/jbmr.2378.
Osteonectin/SPARC is one of the most abundant noncollagenous extracellular matrix proteins in bone, regulating collagen fiber assembly and promoting osteoblast differentiation. Osteonectin-null and haploinsufficient mice have low-turnover osteopenia, indicating that osteonectin contributes to normal
PMID 25262637

A novel splice mutation in PLS3 causes X-linked early onset low-turnover osteoporosis.

Laine CM1, Wessman M, Toiviainen-Salo S, Kaunisto MA, Mäyränpää MK, Laine T, Pekkinen M, Kröger H, Välimäki VV, Välimäki MJ, Lehesjoki AE, Mäkitie O.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.J Bone Miner Res.2015 Mar;30(3):510-8. doi: 10.1002/jbmr.2355.
Genetic factors play an important role in the development of osteoporosis. Several monogenic forms of osteoporosis have been recognized, most recently an X-chromosomal form resulting from mutations in the gene encoding plastin 3 (PLS3). PLS3 is a protein involved in actin bundle formation in the cyt
PMID 25209159

Effect of Locally Applied Fluvastatin in Low-turnover Osteoporosis Model Mouse with Femur Bone Defect

Effect of Locally Applied Fluvastatin in Low-turnover Osteoporosis Model Mouse with Femur Bone Defect

, , , ,
Journal of Hard Tissue Biology 24(2), 147-154, 2015
… The aim of this study was to investigate the effects of local administration of fluvastatin-gelatin complex on the healing of bone defects in low-turnover osteoporosis mice. … Using 20-week-old low-turnover osteoporosis model mice (SAMP6) and normal model mice (SAMR1), cylindrical and bone defects were made in sites 1.0 mm in diameter and depth, 1 mm of 3 mm from both sides of the distal end of the femur. …
NAID 130005065049