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Identification of a novel 6'-N-aminoglycoside acetyltransferase, AAC(6')-Iak, from a multidrug-resistant clinical isolate of Stenotrophomonas maltophilia.

Tada T1, Miyoshi-Akiyama T1, Dahal RK2, Mishra SK2, Shimada K1, Ohara H3, Kirikae T4, Pokhrel BM2.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Oct;58(10):6324-7. doi: 10.1128/AAC.03354-14. Epub 2014 Aug 4.
Stenotrophomonas maltophilia IOMTU250 has a novel 6'-N-aminoglycoside acetyltransferase-encoding gene, aac(6')-Iak. The encoded protein, AAC(6')-Iak, consists of 153 amino acids and has 86.3% identity to AAC(6')-Iz. Escherichia coli transformed with a plasmid containing aac(6')-Iak exhibited decreas
PMID 25092711

Effects of dexamethasone on local infiltration analgesia in total knee arthroplasty: a randomized controlled trial.

Ikeuchi M1, Kamimoto Y, Izumi M, Fukunaga K, Aso K, Sugimura N, Yokoyama M, Tani T.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA.Knee Surg Sports Traumatol Arthrosc.2014 Jul;22(7):1638-43. doi: 10.1007/s00167-013-2367-5. Epub 2013 Jan 11.
PURPOSE: Intraoperative local infiltration analgesia has gained increasing popularity in joint replacement surgery. Because there is considerable variation among drug combinations, analgesic effects of each drug are not well understood. The purpose of this study was to clarify the efficacy of the ad
PMID 23306715

[Detection of 16S rRNA methylase genes and genotypes in ESBLs-producing enterobacteriaceae isolates from urinary tract infections].

Hu TY, Qu JY, Li XJ.
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.Sichuan Da Xue Xue Bao Yi Xue Ban.2014 May;45(3):437-41.
OBJECTIVE: To study the prevalence of 16S rRNA methylase genes in extended-spectrum-lactamascs (ESBLs)-producing Enterobacteriacea, and the correlations of 16S rRNA methylase genes with anminoglycoside resistnace.METHODS: Seventy-four ESBLs-producing Enterobacteriacea stains were isolated from urina
PMID 24941813