iodinated contrast media

ヨード造影剤

WordNet

1. put in opposition to show or emphasize differences; "The middle school teacher contrasted her best students work with that of her weakest student"
2. the opposition or dissimilarity of things that are compared; "in contrast to", "by contrast" (同)direct contrast
3. the act of distinguishing by comparing differences
4. the range of optical density and tone on a photographic negative or print (or the extent to which adjacent areas on a television screen differ in brightness)
5. the perceptual effect of the juxtaposition of very different colors
6. to show differences when compared; be different; "the students contrast considerably in their artistic abilities" (同)counterpoint
7. strikingly different; tending to contrast; "contrasting (or contrastive) colors" (同)contrastive
8. cause to combine with iodine; "iodinate thyroxine"
9. treated with iodine; "iodized salt" (同)iodized, iodised

PrepTutorEJDIC

1. (違いを示すために)(二つのもの)'を'『対照させる』,対比する;(…と)…'を'対照させる《+『名』+『with』+『名』》 / (…と)『対照する』,対照的に引き立つ《+『with』+『名』》 / 〈U〉(…との)『対照』,対比《+『with』(『to』)+『名』》 / 〈C〉〈U〉(…間の)対照的な差,(特に色・明るさの)対照,コントラスト《+『between』+『名』+『and』+『名』》,(…との)著しい相違《+『to』+『名』》 / 〈C〉(…と)対照的な人(物)《+『to』+『名』》
2. mediumの複数形

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/21 19:36:08」(JST)

wiki en

[Wiki en表示]

Iodinated contrast is a form of intravenous radiocontrast (radiographic dye) containing iodine, which enhances the visibility of vascular structures and organs during radiographic procedures. Some pathologies, such as cancer, have particularly improved visibility with iodinated contrast.

Iodinated contrast media may either be oil-based or water-soluble, the former of which is slowly absorbed by body tissue and is usually only used in sialographic and hysterosalpingographic examinations. Water-soluble iodinated medium, which is more quickly absorbed, may be used in place of barium sulfate for gastrointestinal studies that are contraindicated by the use of barium for that reason.

Iodinated medium may also be either ionic or non-ionic. The ionic type tends to create a high osmolality in blood and may cause a contrast media reaction in some individuals, which may be life-threatening for those with certain medical conditions. The non-ionic form decreases this risk, but is much more expensive. The non-ionic contrast media is much more widely used today.

Acute side effects

Shortly after infusion, iodinated contrast medium causes a warming sensation throughout the body. Sometimes this feeling is more pronounced in the pelvic area. Patients receiving contrast via IV typically experience a hot feeling around the throat, and this hot sensation gradually moves down to the pelvic area.

Contrast induced nephropathy

Main article: Contrast-induced nephropathy

Iodinated contrast may be toxic to the kidneys, especially when given via the arteries prior to studies such as catheter coronary angiography. Non-ionic contrast agents, which are almost exclusively used in computed tomography studies, have not been shown to cause CIN when given intravenously at doses needed for CT studies.

Thyroid dysfunction

Iodinated radiocontract can induce overactivity (hyperthyroidism) and underactivity (hypothyroidism) of the thyroid gland. The risk of either condition developing after a single examination is 2-3 times that those who have not undergone a scan with iodinated contrast. Thyroid underactivity is mediated by a phenomenon called the Wolff–Chaikoff effect, where iodine suppresses the production of thyroid hormones; this is usually temporary but there is an association with longer-term thyroid underactivity. Some other people show the opposite effect, called Jod-Basedow phenomenon, where the iodine induces overproduction of thyroid hormone; this may be the result of underlying thyroid disease (such as nodules or Graves' disease) or previous iodine deficiency. Children exposed to iodinated contrast during pregnancy may develop hypothyroidism after birth and monitoring of the thyroid function is recommended.

Further reading

• Bontranger, Kenneth L. & Lampignano, John P. (2005). Radiographic Positioning and Related Anatomy, St. Louis: Elsevier Mosby. ISBN 0-323-02507-2.

References

See also

• Contrast medium

UpToDate Contents

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• 1. ヨード誘発性甲状腺機能異常症 iodine induced thyroid dysfunction
• 2. ヨード欠乏症 iodine deficiency disorders
• 3. 造影剤に対する即時型過敏反応：臨床症状、診断、および治療 immediate hypersensitivity reactions to radiocontrast media clinical manifestations diagnosis and treatment
• 4. 妊娠していない成人におけるグレーブス甲状腺機能亢進症：治療の概要 graves hyperthyroidism in nonpregnant adults overview of treatment
• 5. ヨウ素による甲状腺機能亢進症の治療 iodine in the treatment of hyperthyroidism

English Journal

• Re-exposure to low osmolar iodinated contrast media in patients with prior moderate-to-severe hypersensitivity reactions: A multicentre retrospective cohort study.

• Park HJ1, Park JW2, Yang MS3, Kim MY4, Kim SH5, Jang GC6, Nam YH7, Kim GW8, Kim S9, Park HK10, Jung JW11, Park JS12, Kang HR13.
• European radiology.Eur Radiol.2017 Jul;27(7):2886-2893. doi: 10.1007/s00330-016-4682-y. Epub 2016 Dec 14.
• PMID 27975150

• Iohexol degradation in wastewater and urine by UV-based Advanced Oxidation Processes (AOPs): Process modeling and by-products identification.

• Giannakis S1, Jovic M2, Gasilova N2, Pastor Gelabert M3, Schindelholz S4, Furbringer JM5, Girault H2, Pulgarin C6.
• Journal of environmental management.J Environ Manage.2017 Jun 15;195(Pt 2):174-185. doi: 10.1016/j.jenvman.2016.07.004. Epub 2016 Jul 12.
• PMID 27416798

• Acute generalized exanthematous pustulosis caused by an iodinated contrast radiocontrast medium for computed tomography arthrography of the knee.

• Velter C1, Schissler C1, Moulinas C1, Tebacher-Alt M2, Siedel JM3, Cribier B1, Lipsker D1.
• Contact dermatitis.Contact Dermatitis.2017 Jun;76(6):371-373. doi: 10.1111/cod.12724.
• PMID 28497630

Japanese Journal

• 脳血管のフラクタル性を用いたヨード製剤の動態解析 (イメージ・メディア・クオリティ)

• 内藤 啓介,山元 勇輝,藤井 啓輔 [他]
• 電子情報通信学会技術研究報告 = IEICE technical report : 信学技報 114(386), 23-28, 2014-12-20
• NAID 40020324036

• ヨード造影剤による小腸のangioedema

• 河辺 哲哉,長田 久人,柳田 ひさみ [他]
• 臨床放射線 59(7), 961-965, 2014-07
• NAID 40020139646

• Examination of Patients Suspected as Having Hypersensitivity to Iodinated Contrast Media with Leukocyte Migration Test

• Saito Mikio,Abe Manabu,Furukawa Tomoyasu [他],Yagi Motohiro,Koike Yoshihiro,Wakasugi Yutaka,Tabuchi Norihiko,Uno Katsuji
• Biological and Pharmaceutical Bulletin 37(11), 1750-1757, 2014
• … In vivo tests may be used for the diagnosis of allergy to iodinated contrast media (ICM); …
• NAID 130004703895

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★リンクテーブル★

リンク元	「ヨード造影剤」
関連記事	「media」「med」「contrasting」「iodinate」

「ヨード造影剤」

　　[★]

英

iodinated contrast media, iodine contrast media

関

造影剤

[show details]

よう素系造影剤 : 13 件
よう素性造影剤 : 約 7,510 件
よう素造影剤 : nothing
ヨウ素系造影剤 : 54 件
ヨウ素性造影剤 : nothing
ヨウ素造影剤 : 87 件
ヨード性造影剤 : 64 件
ヨード系造影剤 : 約 27,400 件
ヨード造影剤 : 約 33,000 件

en

iodinated contrast media : 約 741,000 件
iodine contrast media : 約 231,000 件

検査・身体への影響

• アレルギー：アナフィラキシーショック
• 腎機能障害
• 煮沸法、スルフォサリチル酸法による尿蛋白の検査における偽陽性

ヨード造影剤によるアナフィラキシーショック

• 高リスク患者：気管支喘息の既往

「media」

　　[★]

• n.

関

culture、culture media、culture medium、culture solution、medium

　

「med」

　　[★]

• n.

• 医学

関

iatrology、medical、medical science、medicine

「contrasting」

　　[★]

• adj.

• 対照的な

関

by contrast、in contrast

　

「iodinate」

　　[★]

• ヨウ素化する

関

iodination