WordNet

a condition marked by uncontrollable tremor
affect with palsy
become friends; act friendly towards (同)pal up, chum up

PrepTutorEJDIC

麻痺(まひ),中風 / …‘を'麻痺させる(paralyze)
《話》『友達』,仲間,親友 / (…と)仲よくなる《[『up』]『with』+『名』》

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1. 核間性眼筋麻痺 internuclear ophthalmoparesis
2. 成人における詳細な神経学的検査 the detailed neurologic examination in adults
3. 成人における第三脳神経（動眼神経）麻痺 third cranial nerve oculomotor nerve palsy in adults
4. 小児における第3脳神経（動眼神経）麻痺 third cranial nerve oculomotor nerve palsy in children
5. 小児における核上性注視異常 supranuclear disorders of gaze in children

English Journal

Isolated bilateral horizontal gaze palsy as first manifestation of multiple sclerosis.

Kipfer S1, Crook DW.Author information 1Department of Internal Medicine and Neurology, Kantonsspital Olten, Switzerland.AbstractPredilection sites for infratentorial multiple sclerosis lesions are well known and frequently involve the fasciculus longitudinalis medialis leading to classical internuclear ophthalmoplegia. We report a very rare oculomotor disorder due to a demyelinating central nervous system (CNS) lesion in the medial part of the lower pontine tegmentum. A 36-year-old man presented with sudden onset of blurred vision. Clinically there was limited eye adduction and abduction to either side, which corresponds to bilateral horizontal gaze palsy. Brain magnetic resonance imaging (MRI) showed a demyelinating CNS lesion affecting the fasciculus longitudinalis medialis, abducens nuclei or abducens fibres in the medial part of the lower pontine tegmentum. Furthermore there were six further demyelinating white matter lesions fulfilling all Barkhof criteria for multiple sclerosis. Demyelinating CNS lesions causing isolated bilateral horizontal gaze palsy are exceptional and usually associated with further focal neurological deficits, which was not the case in the presenting patient. This is a unique video report of isolated bilateral horizontal gaze palsy as the initial manifestation of demyelinating CNS disease, which lead to definite diagnosis of relapsing remitting multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England).Mult Scler.2014 May;20(6):754-5. doi: 10.1177/1352458513518627. Epub 2014 Jan 8.
Predilection sites for infratentorial multiple sclerosis lesions are well known and frequently involve the fasciculus longitudinalis medialis leading to classical internuclear ophthalmoplegia. We report a very rare oculomotor disorder due to a demyelinating central nervous system (CNS) lesion in the
PMID 24402040

Eight-and-a-Half Syndrome: A Rare Presentation of Pontine Infarction.

Sampath Kumar NS1, Raju CG2, Kiran PR2, Kumar TA2, Gopal BV2, Khaseem DB2.Author information 1Department of Neurology, Narayana Medical College, Nellore, Andhra Pradesh, India. Electronic address: padala6487@gmail.com.2Department of Neurology, Narayana Medical College, Nellore, Andhra Pradesh, India.Abstract"Eight-and-a-half" syndrome is "one-and-a-half" syndrome (conjugated horizontal gaze palsy and internuclear ophthalmoplegia) plus ipsilateral fascicular cranial nerve seventh palsy. This rare condition, particularly when isolated, is caused by circumscribed lesions of the pontine tegmentum involving the abducens nucleus, the ipsilateral medial longitudinal fasciculus, and the adjacent facial colliculus. Its recognition is therefore of considerable diagnostic value. We report a case of a 65-year-old man who presented with eight-and-a-half syndrome in which brain magnetic resonance imaging scan revealed a lacunar pontine infarction.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.J Stroke Cerebrovasc Dis.2014 Mar 25. pii: S1052-3057(14)00026-3. doi: 10.1016/j.jstrokecerebrovasdis.2014.01.002. [Epub ahead of print]
"Eight-and-a-half" syndrome is "one-and-a-half" syndrome (conjugated horizontal gaze palsy and internuclear ophthalmoplegia) plus ipsilateral fascicular cranial nerve seventh palsy. This rare condition, particularly when isolated, is caused by circumscribed lesions of the pontine tegmentum involving
PMID 24674953

Eight and a half syndrome with hemiparesis and hemihypesthesia: the nine syndrome?

Rosini F1, Pretegiani E, Guideri F, Cerase A, Rufa A.Author information 1Eye Tracking & Visual Application Lab, Department of Neurological, Neurosurgical, and Behavioral Sciences, Siena, Italy.Abstract"Eight-and-a-half" syndrome is "one-and-a-half" syndrome (conjugated horizontal gaze palsy and internuclear ophthalmoplegia) plus ipsilateral fascicular cranial nerve seventh palsy. This rare condition, particularly when isolated, is caused by circumscribed lesions of the pontine tegmentum involving the abducens nucleus, the ipsilateral medial longitudinal fasciculus, and the adjacent facial colliculus. Its recognition is therefore of considerable diagnostic value. We report a 71-year-old man who presented with eight and a half syndrome associated with contralateral hemiparesis and hemihypesthesia, in which brain magnetic resonance imaging scans revealed a lacunar pontine infarction also involving the corticospinal tract and medial lemniscus. These features could widen the spectrum of pontine infarctions, configuring a possible "nine" syndrome.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.J Stroke Cerebrovasc Dis.2013 Nov;22(8):e637-8. doi: 10.1016/j.jstrokecerebrovasdis.2013.01.018. Epub 2013 Feb 21.
"Eight-and-a-half" syndrome is "one-and-a-half" syndrome (conjugated horizontal gaze palsy and internuclear ophthalmoplegia) plus ipsilateral fascicular cranial nerve seventh palsy. This rare condition, particularly when isolated, is caused by circumscribed lesions of the pontine tegmentum involving
PMID 23434442

Japanese Journal

Clinicoradiological Analysis of the Oculomotor Fasciculus

Tsuda Hiromasa
Internal Medicine 51(14), 1955-1955, 2012
NAID 130002062258

WEMINO Syndrome with Skew Deviation and Facial Palsy

Tsuda Hiromasa,Kamata Kazuhiro,Tanaka Kozue,Kishida Shuji
Internal Medicine 50(20), 2435-2436, 2011
NAID 130001087766

One-and-a-half 症候群ならびに顔面神経麻痺で発症した多発性硬化症例

岡田昌浩,澤井尚樹,兵頭純 [他],羽藤直人,暁清文
耳鼻咽喉科臨床 103(6), 517-521, 2010-06-01
… A 35-year-old man who was referred to our hospital 6 days after diplopia, dizziness and left hemifacial palsy had experienced left facial palsy 8 years earlier. … conjugate left-side lateral gaze palsy and impaired left-eye adduction and for the right eye, gaze nystagmus induction in the right-side gaze. …
NAID 10026361850