WordNet

fasten or secure with chains; "Chain the chairs together"
a unit of length
a necklace made by a stringing objects together; "a string of beads"; "a strand of pearls"; (同)string, strand
a linked or connected series of objects; "a chain of daisies"
a series of (usually metal) rings or links fitted into one another to make a flexible ligament
anything that acts as a restraint
(chemistry) a series of linked atoms (generally in an organic molecule) (同)chemical chain
a series of things depending on each other as if linked together; "the chain of command"; "a complicated concatenation of circumstances" (同)concatenation
(business) a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership
connect or arrange into a chain by linking
give birth to a lamb; "the ewe lambed"
young sheep
a sweet innocent mild-mannered person (especially a child) (同)dear
a person easily deceived or cheated (especially in financial matters)
the flesh of a young domestic sheep eaten as food
the 11th letter of the Greek alphabet
the craniometric point at the junction of the sagittal and lamboid sutures of the skull
a class of proteins produced in lymph tissue in vertebrates and that function as antibodies in the immune response (同)Ig, immune serum globulin, immune gamma globulin, immune_globulin
British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906-1979) (同)Ernst Boris Chain, Sir Ernst Boris Chain

PrepTutorEJDIC

『鎖』;(装飾用の)鎖 / 《複数形で》『束縛』,拘束;囚人をつなぐ鎖 / (物事の)『連続』,つながり《+『of』+『名』》 / (商店・銀行・ホテルなどの)チェーン(一連の店が同一資本のもとで連携して経営される方式;その店) / チェーン(測量で用いられる単位;約21.7m) / …'を'『鎖でつなぐ』《+『up』(『together』)+『名,』+『名』+『up』(『together』)》
〈C〉『子羊』 / 〈U〉子羊の肉 / 〈U〉=lambskin / 《the L-》神の子,キリスト(Christ) / 〈C〉気だてのやさしい(柔和な)人,無邪気な人 / 〈羊が〉子を産む
ラムダ(ギリシア語アルファベットの第11字Λ,λ;英語のL,lに相当)

UpToDate Contents

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1. 免疫グロブリンの構造 structure of immunoglobulins
2. 免疫グロブリン軽鎖（AL）アミロイドーシスおよび軽鎖重鎖沈着症の病因 pathogenesis of immunoglobulin light chain al amyloidosis and light and heavy chain deposition diseases
3. 免疫グロブリン軽鎖（AL）アミロイドーシス（原発性アミロイドーシス）の臨床像、検査所見、および診断 clinical presentation laboratory manifestations and diagnosis of immunoglobulin light chain al amyloidosis primary amyloidosis
4. 意義未確定の単クローン性免疫グロブリン血症（MGUS）の診断 diagnosis of monoclonal gammopathy of undetermined significance
5. 免疫グロブリン静脈内投与（IVIG）療法の概要 overview of intravenous immune globulin ivig therapy

English Journal

Free light chain monomer-dimer patterns in the diagnosis of multiple sclerosis.

Kaplan B, Golderman S, Yahalom G, Yeskaraev R, Ziv T, Aizenbud BM, Sela BA, Livneh A.SourceHeller Institute of Medical Research, Sheba Medical Center, Tel-Hashomer, Israel. Electronic address: batiakaplan@gmail.com.
Journal of immunological methods.J Immunol Methods.2013 Apr 30;390(1-2):74-80. doi: 10.1016/j.jim.2013.01.010. Epub 2013 Jan 31.
In our search of new biomarkers for multiple sclerosis (MS), we aimed to characterize the immunoglobulin (Ig) free light chains (FLC) in patients' cerebrospinal fluid (CSF) and serum, and to evaluate the diagnostic utility of FLC monomer-dimer patterns for MS. FLC were analyzed by Western blotting a
PMID 23376556

Chronic myopathy due to immunoglobulin light chain amyloidosis.

Manoli I, Kwan JY, Wang Q, Rushing EJ, Tsokos M, Arai AE, Burch WM, Dispenzieri A, McPherron AC, Gahl WA.SourceSection on Human Biochemical Genetics, Medical Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA; Intramural Program, Office of Rare Diseases Research, NIH, Bethesda, MD, USA; NIH Undiagnosed Diseases Program, NIH, Bethesda, MD, USA. Electronic address: manolii@mail.nih.gov.
Molecular genetics and metabolism.Mol Genet Metab.2013 Apr;108(4):249-54. doi: 10.1016/j.ymgme.2013.01.015. Epub 2013 Feb 4.
Amyloid myopathy associated with a plasma cell dyscrasia is a rare cause of muscle hypertrophy. It can be a challenging diagnosis, since pathological findings are often elusive. In addition, the mechanism by which immunoglobulin light-chain deposition stimulates muscle overgrowth remains poorly unde
PMID 23465863

Combinatorial Analysis of Secretory Immunoglobulin A (sIgA) Expression in Plants.

Juarez P, Huet-Trujillo E, Sarrion-Perdigones A, Falconi EE, Granell A, Orzaez D.SourceInstitute of Molecular and Cellular Plant Biology (IBMCP), Spanish Research Council Agency (CSIC), Polytechnic University of Valencia (UPV), Avda Tarongers SN, Valencia 46022, Spain. dorzaez@ibmcp.upv.es.
International journal of molecular sciences.Int J Mol Sci.2013 Mar 18;14(3):6205-22. doi: 10.3390/ijms14036205.
Delivery of secretory immunoglobulin A (sIgA) to mucosal surfaces as a passive immunotherapy agent is a promising strategy to prevent infectious diseases. Recombinant sIgA production in plants requires the co-expression of four transcriptional units encoding the light chain (LC), heavy chain (HC), j
PMID 23507755

Japanese Journal

形質細胞歯肉炎の1例

井上雄,山田容三,松川聡,金井一哉,千葉博茂,草間博
日本口腔外科学会雑誌 45(1), 19-21, 1999-01-20
… Moreover, many cells stained positively with monoclonal antibody against anti-immunoglobulin kappa chain and anti-immunoglobulin lambda chain on immunohistological analysis. …
NAID 10005073772

ラテックス凝集免疫測定法による尿中遊離L鎖定量の臨床的意義について

大谷慎一,大谷英樹
北里医学 28(5), 435-445, 1998-10-31
… 我々は尿中免疫グロブリン遊離L鎖(free light chain: FL鎖)の定量法として新しいLatex agglutination immunoassay (LAIA)を開発し,本法を用いてその臨床的意義について検討した。 …
NAID 110004697126